{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:24:33Z","timestamp":1761708273145},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1097\/pas.0b013e3181709fbf","type":"journal-article","created":{"date-parts":[[2008,10,21]],"date-time":"2008-10-21T07:09:45Z","timestamp":1224572985000},"page":"1715-1720","source":"Crossref","is-referenced-by-count":59,"title":["p16ink4a and HPV L1 Immunohistochemistry is Helpful for Estimating the Behavior of Low-grade Dysplastic Lesions of the Cervix Uteri"],"prefix":"10.1097","volume":"32","author":[{"given":"Giovanni","family":"Negri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Bellisano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian Franco","family":"Zannoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Rivasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armin","family":"Kasal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Vittadello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Antoniazzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavino","family":"Faa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rossano","family":"Ambu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduard","family":"Egarter-Vigl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-15-20210131","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1097\/01.MP.0000077518.78046.0C","article-title":"p16(INK4a) expression correlates with degree of cervical neoplasia: a comparison with Ki-67 expression and detection of high-risk HPV types","volume":"16","author":"Agoff","year":"2003","journal-title":"Mod Pathol"},{"key":"R2-15-20210131","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.ejogrb.2004.11.024","article-title":"Detection and typing of human papillomavirus DNA in uterine cervices with coexistent grade I and grade III intraepithelial neoplasia: biologic progression or independent lesions?","volume":"121","author":"Agorastos","year":"2005","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R3-15-20210131","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1038\/modpathol.3800551","article-title":"Immunohistochemical expression of p16(INK4a) is predictive of HR-HPV infection in cervical low-grade lesions","volume":"19","author":"Benevolo","year":"2006","journal-title":"Mod Pathol"},{"issue":"1","key":"R4-15-20210131","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1016\/j.jcv.2004.12.006","article-title":"The papillomavirus life cycle","volume":"32","author":"Doorbar","year":"2005","journal-title":"J Clin Virol"},{"key":"R5-15-20210131","first-page":"241","article-title":"Correlation of immunochemical detection of HPV L1 capsid protein in pap smears with regression of high-risk HPV positive mild\/moderate dysplasia","volume":"26","author":"Griesser","year":"2004","journal-title":"Anal Quant Cytol Histol"},{"key":"R6-15-20210131","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1097\/00000478-200107000-00006","article-title":"Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia","volume":"25","author":"Keating","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"R7-15-20210131","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1002\/ijc.1174","article-title":"Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri","volume":"92","author":"Klaes","year":"2001","journal-title":"Int J Cancer"},{"key":"R8-15-20210131","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1097\/00000478-200211000-00001","article-title":"p16INK4a immunohistochemistry improves interobserver agreement in the diagnosis of cervical intraepithelial neoplasia","volume":"26","author":"Klaes","year":"2002","journal-title":"Am J Surg Pathol"},{"key":"R9-15-20210131","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1159\/000326491","article-title":"Immunocytochemical detection of HPV high-risk type L1 capsid proteins in LSIL and HSIL as compared with detection of HPV L1 DNA","volume":"47","author":"Melsheimer","year":"2003","journal-title":"Acta Cytol"},{"key":"R10-15-20210131","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/00000478-200302000-00006","article-title":"p16INK4a is a useful marker for the diagnosis of adenocarcinoma of the cervix uteri and its precursors: an immunohistochemical study with immunocytochemical correlations","volume":"27","author":"Negri","year":"2003","journal-title":"Am J Surg Pathol"},{"key":"R11-15-20210131","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1007\/s00428-004-1127-9","article-title":"p16INK4a expression and progression risk of low-grade intraepithelial neoplasia of the cervix uteri","volume":"445","author":"Negri","year":"2004","journal-title":"Virchows Arch"},{"key":"R12-15-20210131","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.pap.0000201828.92719.f3","article-title":"p16 expression in the female genital tract and its value in diagnosis","volume":"13","author":"O'Neill","year":"2006","journal-title":"Adv Anat Pathol"},{"key":"R13-15-20210131","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1097\/00004347-199304000-00018","article-title":"Natural history of cervical intraepithelial neoplasia: a critical review","volume":"12","author":"Ost\u00f6r","year":"1993","journal-title":"Int J Gynecol Pathol"},{"key":"R14-15-20210131","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1006\/gyno.1998.5100","article-title":"Coexistence of low and high grade squamous intraepithelial lesions of the cervix: morphologic progression or multiple papillomaviruses?","volume":"70","author":"Park","year":"1998","journal-title":"Gynecol Oncol"},{"key":"R15-15-20210131","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1016\/S0002-9440(10)65689-1","article-title":"Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions","volume":"153","author":"Sano","year":"1998","journal-title":"Am J Pathol"},{"key":"R16-15-20210131","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1111\/j.1440-1827.1998.tb03954.x","article-title":"Immunohistochemical overexpression of p16 protein associated with intact retinoblastoma protein expression in cervical cancer and cervical intraepithelial neoplasia","volume":"48","author":"Sano","year":"1998","journal-title":"Pathol Int"},{"key":"R17-15-20210131","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1001\/jama.285.11.1500","article-title":"Atypical Squamous Cells of Undetermined Significance-Low-grade Squamous Intraepithelial Lesion Triage Study (ALTS) group. Interobserver reproducibility of cervical cytologic and histologic interpretations: realistic estimates from the ASCUS-LSIL Triage Study","volume":"285","author":"Stoler","year":"2001","journal-title":"JAMA"},{"key":"R18-15-20210131","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1016\/S0959-8049(02)00462-8","article-title":"New markers for cervical dysplasia to visualise the genomic chaos created by aberrant oncogenic papillomavirus infections","volume":"38","author":"von Knebel Doeberitz","year":"2002","journal-title":"Eur J Cancer"}],"container-title":["American Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.lww.com\/00000478-200811000-00015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,19]],"date-time":"2021-09-19T06:04:12Z","timestamp":1632031452000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00000478-200811000-00015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":18,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/pas.0b013e3181709fbf","relation":{},"ISSN":["0147-5185"],"issn-type":[{"value":"0147-5185","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]}}}