{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:59:27Z","timestamp":1790981967156,"version":"4.1.0"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,11]]},"DOI":"10.1097\/pas.0b013e3181accb01","type":"journal-article","created":{"date-parts":[[2009,10,22]],"date-time":"2009-10-22T03:26:22Z","timestamp":1256181982000},"page":"1594-1600","source":"Crossref","is-referenced-by-count":37,"title":["Overlapping Features Between Dedifferentiated Liposarcoma and Undifferentiated High-Grade Pleomorphic Sarcoma"],"prefix":"10.1097","volume":"33","author":[{"given":"Lawrance","family":"Chung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean K.","family":"Lau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Loera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Bedel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianling","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence M.","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiguo G.","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-3-20210131","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1097\/01.pas.0000170343.09562.39","article-title":"MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data","volume":"29","author":"Binh","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"R2-3-20210131","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1309\/VMBP67QUNN6Q3J0E","article-title":"Reproducibility of MDM2 and CDK4 staining in soft tissue tumors","volume":"125","author":"Binh","year":"2006","journal-title":"Am J Clin Pathol"},{"key":"R3-3-20210131","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1097\/PAS.0b013e31804b4109","article-title":"Dedifferentiated liposarcomas with divergent myosarcomatous differentiation developed in the internal trunk: a study of 27 cases and comparison to conventional dedifferentiated liposarcomas and leiomyosarcomas","volume":"31","author":"Binh","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"R4-3-20210131","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/01.MP.0000056983.78547.77","article-title":"Most malignant fibrous histiocytomas developed in the retroperitoneum are dedifferentiated liposarcomas: a review of 25 cases initially diagnosed as malignant fibrous histiocytoma","volume":"16","author":"Coindre","year":"2003","journal-title":"Mod Pathol"},{"key":"R5-3-20210131","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1002\/path.1579","article-title":"Inflammatory malignant fibrous histiocytomas and dedifferentiated liposarcomas: histological review, genomic profile, and MDM2 and CDK4 status favour a single entity","volume":"203","author":"Coindre","year":"2004","journal-title":"J Pathol"},{"key":"R6-3-20210131","first-page":"95","article-title":"S-100 protein staining in liposarcoma. Its diagnostic utility in the high grade myxoid (round cell) variant","volume":"4","author":"dei Tos","year":"1996","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"R7-3-20210131","first-page":"120","article-title":"Tumor of Soft Tissue and Bone","author":"Fletcher","year":"2002"},{"key":"R8-3-20210131","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/00000478-199703000-00002","article-title":"Dedifferentiated liposarcoma: a clinicopathological analysis of 155 cases with a proposal for an expanded definition of dedifferentiation","volume":"21","author":"Henricks","year":"1997","journal-title":"Am J Surg Pathol"},{"key":"R9-3-20210131","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/modpathol.3801017","article-title":"Immunostaining for peroxisome proliferator gamma distinguishes dedifferentiated liposarcoma from other retroperitoneal sarcomas","volume":"21","author":"Horvai","year":"2008","journal-title":"Mod Pathol"},{"key":"R10-3-20210131","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1002\/ijc.23380","article-title":"HMGA2 is the partner of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon","volume":"122","author":"Italiano","year":"2008","journal-title":"Int J Cancer"},{"key":"R11-3-20210131","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1097\/00000478-199412000-00004","article-title":"Dedifferentiated liposarcoma. Clinicopathologic analysis of 32 cases suggesting a better prognostic subgroup among pleomorphic sarcomas","volume":"18","author":"McCormick","year":"1994","journal-title":"Am J Surg Pathol"},{"key":"R12-3-20210131","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s004280100423","article-title":"Cytogenetic and molecular genetic analyses of liposarcoma and its soft tissue simulators: recognition of new variants and differential diagnosis","volume":"439","author":"Meis-Kindblom","year":"2001","journal-title":"Virchows Arch"},{"key":"R13-3-20210131","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/(SICI)1096-9896(199806)185:2<188::AID-PATH53>3.0.CO;2-2","article-title":"Molecular abnormalities in liposarcoma: role of MDM2 and CDK4-containing amplicons at 12q13-22","volume":"185","author":"Pilotti","year":"1998","journal-title":"J Pathol"},{"key":"R14-3-20210131","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1007\/s004320050211","article-title":"MDM2 amplification and loss of heterozygosity at Rb and p53 genes: no simultaneous alterations in the oncogenesis of liposarcomas","volume":"124","author":"Schneider-Stock","year":"1998","journal-title":"J Cancer Res Clin Oncol"},{"key":"R15-3-20210131","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/1098-2264(2000)9999:9999<::AID-GCC1014>3.0.CO;2-Q","article-title":"Characterization of centromere alterations in liposarcomas","volume":"29","author":"Sirvent","year":"2000","journal-title":"Genes Chromosomes Cancer"},{"key":"R16-3-20210131","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1097\/PAS.0b013e3180581fff","article-title":"Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR","volume":"31","author":"Sirvent","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"R17-3-20210131","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1365-2559.2007.02936.x","article-title":"Sclerosing poorly differentiated liposarcoma: clinicopathological, immunohistochemical and molecular analysis of a distinct morphological subtype of lipomatous tumour of soft tissue","volume":"52","author":"Suster","year":"2008","journal-title":"Histopathology"},{"key":"R18-3-20210131","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/(SICI)1098-2264(199602)15:2<89::AID-GCC2>3.0.CO;2-#","article-title":"Gains and losses of DNA sequences in liposarcomas evaluated by comparative genomic hybridization","volume":"15","author":"Szymanska","year":"1996","journal-title":"Genes Chromosomes Cancer"},{"key":"R19-3-20210131","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0165-4608(96)00436-0","article-title":"Overrepresentation of 1q21-23 and 12q13-21 in lipoma-like liposarcomas but not in benign lipomas: a comparative genomic hybridization study","volume":"99","author":"Szymanska","year":"1997","journal-title":"Cancer Genet Cytogenet"},{"key":"R20-3-20210131","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1101\/gad.8.10.1224","article-title":"mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer","volume":"8","author":"Tontonoz","year":"1994","journal-title":"Genes Dev"},{"key":"R21-3-20210131","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1097\/01.pas.0000213257.69478.2f","article-title":"Formation of the 12q14-q15 amplicon precedes the development of a well-differentiated liposarcoma arising from a nonchondroid pulmonary hamartoma","volume":"30","author":"Trahan","year":"2006","journal-title":"Am J Surg Pathol"},{"key":"R22-3-20210131","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1038\/modpathol.2008.84","article-title":"Fluorescence in situ hybridization for MDM2 gene amplification as a diagnostic tool in lipomatous neoplasms","volume":"21","author":"Weaver","year":"2008","journal-title":"Mod Pathol"}],"container-title":["American Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00000478-200911000-00003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:04:38Z","timestamp":1786039478000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00000478-200911000-00003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":22,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/pas.0b013e3181accb01","relation":{},"ISSN":["0147-5185"],"issn-type":[{"value":"0147-5185","type":"print"}],"subject":[],"published":{"date-parts":[[2009,11]]}}}