{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:07:37Z","timestamp":1787771257369,"version":"build-2784847793"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1097\/pas.0b013e31823732a9","type":"journal-article","created":{"date-parts":[[2011,11,12]],"date-time":"2011-11-12T11:15:26Z","timestamp":1321096526000},"page":"368-375","source":"Crossref","is-referenced-by-count":77,"title":["Low-Grade Ovarian Serous Neoplasms (Low-Grade Serous Carcinoma and Serous Borderline Tumor) Associated With High-Grade Serous Carcinoma or Undifferentiated Carcinoma"],"prefix":"10.1097","volume":"36","author":[{"given":"Clinton","family":"Boyd","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Glenn","family":"McCluggage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-6-20210131","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/path.2696","article-title":"Driver mutations in TP53 are ubiquitous in high grade serous carcinomas of the ovary.","volume":"221","author":"Ahmed","year":"2010","journal-title":"J Pathol"},{"key":"R3-6-20210131","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1097\/PAS.0b013e31802cbbe9","article-title":"The development of high-grade serous carcinoma from atypical proliferative (borderline) serous tumours and low-grade micropapilary serous carcinoma: a morphologic and molecular genetic analysis.","volume":"31","author":"Dehari","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"R4-6-20210131","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1097\/01.pgp.0000130446.84670.93","article-title":"Subclassification of ovarian surface epithelial tumors based on correlation of histologic and molecular pathologic data.","volume":"23","author":"Gilks","year":"2004","journal-title":"Int J Gynecol Pathol"},{"key":"R5-6-20210131","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/path.2630","article-title":"The emerging role of the distal fallopian tube and p53 in pelvic serous carcinogenesis.","volume":"220","author":"Herrington","year":"2010","journal-title":"J Pathol"},{"key":"R6-6-20210131","doi-asserted-by":"crossref","first-page":"6915","DOI":"10.1158\/0008-5472.CAN-04-2067","article-title":"Mutations of BRAF and KRAS precede the development of ovarian serous borderline tumors.","volume":"64","author":"Ho","year":"2004","journal-title":"Can Res"},{"key":"R7-6-20210131","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/01.pas.0000213335.40358.47","article-title":"Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationship.","volume":"31","author":"Kindelberger","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"R8-6-20210131","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/PGP.0b013e3181c042b6","article-title":"Differences in tumor type in low-stage versus high-stage ovarian carcinomas.","volume":"29","author":"Kobel","year":"2010","journal-title":"Int J Gynecol Pathol"},{"key":"R9-6-20210131","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/path.2744","article-title":"The biological and clinical value of p53 expression in pelvic high-grade serous carcinomas.","volume":"222","author":"Kobel","year":"2010","journal-title":"J Pathol"},{"key":"R10-6-20210131","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1097\/PAS.0b013e318216c112","article-title":"A comprehensive analysis of PAX8 expression in human epithelial tumors.","volume":"35","author":"Laury","year":"2011","journal-title":"Am J Surg Pathol"},{"key":"R11-6-20210131","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.pap.0000201826.46978.e5","article-title":"Advances in the recognition of tubal intraepithelial carcinoma: applications to cancer screening and the pathogenesis of ovarian cancer.","volume":"13","author":"Lee","year":"2006","journal-title":"Adv Anat Pathol"},{"key":"R12-6-20210131","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/path.2091","article-title":"A candidate precursor to serous carcinoma that originates in the distal fallopian tube.","volume":"211","author":"Lee","year":"2007","journal-title":"J Pathol"},{"key":"R13-6-20210131","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1097\/00000478-200404000-00009","article-title":"Grading ovarian serous carcinoma using a two-tier system.","volume":"28","author":"Malpica","year":"2004","journal-title":"Am J Surg Pathol"},{"key":"R14-6-20210131","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1097\/PAS.0b013e31803199b0","article-title":"Interobserver and intraobserver variability of a two-tier system for grading ovarian serous carcinoma.","volume":"31","author":"Malpica","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"R15-6-20210131","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1136\/jcp.2007.049478","article-title":"My approach to and thoughts on typing of ovarian carcinomas.","volume":"61","author":"McCluggage","year":"2008","journal-title":"J Clin Pathol"},{"key":"R16-6-20210131","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1097\/PAT.0b013e328348a6e7","article-title":"Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis.","volume":"43","author":"McCluggage","year":"2011","journal-title":"Pathology"},{"key":"R18-6-20210131","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/01.pas.0000180854.28831.77","article-title":"The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome.","volume":"30","author":"Medeiros","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"R19-6-20210131","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1097\/PAS.0b013e31816d71ad","article-title":"Expression of pax8 as a useful marker in distinguishing ovarian carcinomas from mammary carcinomas.","volume":"32","author":"Nonaka","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"R20-6-20210131","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1097\/01.pas.0000166367.68459.7d","article-title":"An immunohistochemical comparison between low-grade and high-grade ovarian serous carcinomas. Significantly higher expression of p53, MIB1, bcl2, her-2neu and C-KIT in high-grade neoplasms.","volume":"29","author":"ONeill","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"R21-6-20210131","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1097\/01.pgp.0000130049.19643.f6","article-title":"Early recurrence of ovarian serous borderline tumour as high-grade carcinoma: report of two cases.","volume":"23","author":"Parker","year":"2004","journal-title":"Int J Gynecol Pathol"},{"key":"R22-6-20210131","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1097\/PAS.0b013e3181451b93","article-title":"Anaplastic carcinoma in mucinous ovarian tumors: a clinicopathologic study of 34 cases emphasizing the crucial impact of stage on prognosis, their histologic spectrum, and overlap with sarcomalike mural nodules.","volume":"32","author":"Provenza","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"R24-6-20210131","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1111\/j.1365-2559.2009.03283.x","article-title":"High-grade serous carcinoma arising in a low-grade serous carcinoma and micropapillary serous borderline tumour of the ovary in a 23 year-old woman.","volume":"54","author":"Quddus","year":"2009","journal-title":"Histopathology"},{"key":"R25-6-20210131","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1097\/01.pas.0000138178.10829.b8","article-title":"Endocervical-like mucinous borderline tumors of the ovary: a clinicopathologic analysis of 31 cases.","volume":"28","author":"Rodriguez","year":"2004","journal-title":"Am J Surg Pathol"},{"key":"R26-6-20210131","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1002\/path.1563","article-title":"A multistep model for ovarian tumorigenesis: the value of mutation analysis in the KRAS and BRAF genes.","volume":"203","author":"Russell","year":"2004","journal-title":"J Pathol"},{"key":"R27-6-20210131","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1097\/01.pgp.0000101080.35393.16","article-title":"The histologic type and stage distribution of ovarian carcinomas of surface epithelial origin.","volume":"23","author":"Seidman","year":"2004","journal-title":"Int J Gynecol Pathol"},{"key":"R28-6-20210131","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/S0002-9440(10)63708-X","article-title":"Ovarian tumorigenesis. A proposed model based on morphological and molecular genetic analysis.","volume":"164","author":"Shih","year":"2004","journal-title":"Am J Pathol"},{"key":"R29-6-20210131","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/path.1521","article-title":"In ovarian neoplasms, BRAF, but not KRAS, mutation are restricted to low-grade serous tumours.","volume":"202","author":"Sieben","year":"2004","journal-title":"J Pathol"},{"key":"R31-6-20210131","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1080\/00313020601159494","article-title":"Undifferentiated carcinoma of the endometrium: a review.","volume":"39","author":"Silva","year":"2007","journal-title":"Pathology"},{"key":"R32-6-20210131","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/S0002-9440(10)62549-7","article-title":"Diverse tumorigenic pathways in ovarian serous carcinoma.","volume":"160","author":"Singer","year":"2002","journal-title":"Am J Pathol"},{"key":"R33-6-20210131","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/00004347-200301000-00009","article-title":"Mutational analysis of K-ras segregates ovarian serous carcinomas into two types: invasive MPSC (low-grade tumor) and conventional serous carcinoma.","volume":"22","author":"Singer","year":"2003","journal-title":"Int J Gynecol Pathol"},{"key":"R34-6-20210131","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/01.pas.0000146025.91953.8d","article-title":"Patterns of p53 mutations separate ovarian serous borderline tumors and low and high grade carcinomas and provide support for a new model of ovarian carcinogenesis: a mutational analysis with immunohistochemical correlation.","volume":"29","author":"Singer","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"R35-6-20210131","first-page":"161","article-title":"Histologic subtypes of ovarian carcinoma: an overview.","volume":"27","author":"Soslow","year":"2008","journal-title":"Int J Gynecol Pathol"},{"key":"R36-6-20210131","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1097\/00000478-199409000-00005","article-title":"Ovarian serous borderline tumors with lymph node involvement. Clinicopathologic and DNA content study of seven cases and review of the literature.","volume":"18","author":"Tan","year":"1994","journal-title":"Am J Surg Pathol"},{"key":"R38-6-20210131","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1097\/PAS.0b013e3182260735","article-title":"Pax8 expression in thymic epithelial neoplasms: an immunohistochemical analysis.","volume":"35","author":"Weissferdt","year":"2011","journal-title":"Am J Surg Pathol"}],"container-title":["American Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/PAS.0b013e31823732a9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T06:55:49Z","timestamp":1639637749000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00000478-201203000-00006"}},"subtitle":["Report of a Series of Cases of an Unusual Phenomenon"],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/pas.0b013e31823732a9","relation":{},"ISSN":["0147-5185"],"issn-type":[{"value":"0147-5185","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}