{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:33:23Z","timestamp":1786120403898,"version":"build-2736575974"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1097\/pas.0b013e318240590a","type":"journal-article","created":{"date-parts":[[2012,2,7]],"date-time":"2012-02-07T07:24:20Z","timestamp":1328599460000},"page":"534-543","source":"Crossref","is-referenced-by-count":39,"title":["Gamma Heavy-chain Disease"],"prefix":"10.1097","volume":"36","author":[{"given":"Shannon","family":"Bieliauskas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond R.","family":"Tubbs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris M.","family":"Bacon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camellia","family":"Eshoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Foucar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E.","family":"Gibson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven H.","family":"Kroft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliyah R.","family":"Sohani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven H.","family":"Swerdlow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James R.","family":"Cook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-6-20210131","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.1182\/blood-2004-07-2755","article-title":"Immunoproliferative small intestinal disease (IPSID): a model for mature B-cell neoplasms.","volume":"105","author":"Al-Saleem","year":"2005","journal-title":"Blood"},{"key":"R3-6-20210131","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1097\/00000478-200106000-00005","article-title":"Is lymphoplasmacytic lymphomaimmunocytoma a distinct entity A clinicopathologic study of 20 cases.","volume":"25","author":"Andriko","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"R4-6-20210131","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.4049\/jimmunol.141.5.1738","article-title":"Gene mutations and alternate RNA splicing result in truncated Ig L chains in human gamma H chain disease.","volume":"141","author":"Cogne","year":"1988","journal-title":"J Immunol"},{"key":"R5-6-20210131","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.humpath.2003.10.014","article-title":"Lack of PAX5 rearrangements in lymphoplasmacytic lymphomas: reassessing the reported association with t(9;14).","volume":"35","author":"Cook","year":"2004","journal-title":"Hum Pathol"},{"key":"R8-6-20210131","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/S0889-8588(05)70127-1","article-title":"Heavy-chain diseases.","volume":"13","author":"Fermand","year":"1999","journal-title":"HematolOncol Clin N Am"},{"key":"R9-6-20210131","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/00005792-198911000-00001","article-title":"Gamma heavy chain disease: heterogeneity of the clinicopathologic features. Report of 16 cases and review of the literature.","volume":"68","author":"Fermand","year":"1989","journal-title":"Medicine"},{"key":"R10-6-20210131","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/0002-9343(64)90191-3","article-title":"Heavy chain diseasea new disorder of serum gamma-globulins : report of the first case.","volume":"37","author":"Franklin","year":"1964","journal-title":"Am J Med"},{"key":"R11-6-20210131","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/S1525-1578(10)60563-6","article-title":"Low-grade B-cell lymphomas with plasmacytic differentiation lack PAX5 gene rearrangements.","volume":"7","author":"George","year":"2005","journal-title":"J Mol Diagn"},{"key":"R13-6-20210131","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1365-3083.1992.tb02961.x","article-title":"Unusual sequence of immunoglobulin L-chain rearrangements in a gamma heavy chain disease patient.","volume":"36","author":"Hauke","year":"1992","journal-title":"Scand J Immunol"},{"key":"R16-6-20210131","doi-asserted-by":"crossref","first-page":"4110","DOI":"10.1182\/blood.V88.11.4110.4110","article-title":"The t(9;14)(p13;q32) chromosomal translocation associated with lymphoplasmacytoid lymphoma involves the PAX-5 gene.","volume":"88","author":"Iida","year":"1996","journal-title":"Blood"},{"key":"R17-6-20210131","first-page":"439","article-title":"The diverse picture of gamma heavy-chain disease. Report of seven cases and review of literature.","volume":"56","author":"Kyle","year":"1981","journal-title":"Mayo Clin Proc"},{"key":"R18-6-20210131","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/jcla.20233","article-title":"Gamma heavy chain disease in a patient with diabetes and chronic renal insufficiency: diagnostic assessment of the heavy chain fragment.","volume":"22","author":"Lee","year":"2008","journal-title":"J Clin Lab Anal"},{"key":"R19-6-20210131","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1309\/AJCP8FOIVTB6LBER","article-title":"Lymphoplasmacytic lymphoma and other non-marginal zone lymphomas with plasmacytic differentiation.","volume":"136","author":"Lin","year":"2011","journal-title":"Am J Clin Pathol"},{"key":"R20-6-20210131","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1258\/acb.2010.010146","article-title":"Monoclonal free light chains can be found in heavy chain diseases.","volume":"47","author":"Lopez-Anglada","year":"2010","journal-title":"Ann Clin Biochem"},{"key":"R21-6-20210131","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1309\/AJCP63OGXHXCSKSC","article-title":"Marginal zone lymphomas with plasmacytic differentiation and related disorders.","volume":"136","author":"Molina","year":"2011","journal-title":"Am J Clin Pathol"},{"key":"R22-6-20210131","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1258\/000456306776021490","article-title":"Unusual gamma heavy chain disease protein in a patient with splenic marginal-zone lymphoma.","volume":"43","author":"Morita","year":"2006","journal-title":"Ann Clin Biochem"},{"key":"R23-6-20210131","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1056\/NEJMcpc0800959","article-title":"Case records of the Massachusetts General Hospital. Case 13-2008. A 46-year-old man with rheumatoid arthritis and lymphadenopathy.","volume":"358","author":"Munshi","year":"2008","journal-title":"N Engl J Med"},{"key":"R24-6-20210131","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1097\/01.pas.0000249445.28713.88","article-title":"Extranodal marginal zone B-cell lymphomas of the ocular adnexa: multiparameter analysis of 34 cases including interphase molecular cytogenetics and PCR for Chlamydia psittaci.","volume":"31","author":"Ruiz","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"R25-6-20210131","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1097\/00130404-200509000-00003","article-title":"Immunoproliferative small intestinal disease: current concepts.","volume":"11","author":"Salem","year":"2005","journal-title":"Cancer J"},{"key":"R26-6-20210131","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1097\/PAS.0b013e3181758806","article-title":"Fluorescence immunophenotypic and interphase cytogenetic characterization of nodal lymphoplasmacytic lymphoma.","volume":"32","author":"Sargent","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"R29-6-20210131","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1006\/bcmd.2000.0294","article-title":"Gamma heavy chain disease in man: independent structural abnormalities and reduced transcription of a functionally rearranged lambda L-chain gene result in the absence of L-chains.","volume":"26","author":"Teng","year":"2000","journal-title":"Blood Cells Mol Dis"},{"key":"R30-6-20210131","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1038\/sj.leu.2403202","article-title":"Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.","volume":"17","author":"van Dongen","year":"2003","journal-title":"Leukemia"},{"key":"R31-6-20210131","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.beha.2005.01.029","article-title":"Heavy chain diseases.","volume":"18","author":"Wahner-Roedler","year":"2005","journal-title":"Best Pract Res"},{"key":"R32-6-20210131","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1097\/01.md.0000085058.63483.7f","article-title":"Gamma-heavy chain disease: review of 23 cases.","volume":"82","author":"Wahner-Roedler","year":"2003","journal-title":"Medicine"},{"key":"R33-6-20210131","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1093\/ajcp\/78.4.427","article-title":"The histopathology of gamma heavy-chain disease.","volume":"78","author":"Wester","year":"1982","journal-title":"Am J Clin Pathol"},{"key":"R34-6-20210131","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s11864-002-0014-3","article-title":"Heavy chain disease.","volume":"3","author":"Witzig","year":"2002","journal-title":"Curr Treat Options Oncol"}],"container-title":["American Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/PAS.0b013e318240590a","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T20:38:57Z","timestamp":1786048737000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00000478-201204000-00006"}},"subtitle":["Defining the Spectrum of Associated Lymphoproliferative Disorders Through Analysis of 13 Cases"],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/pas.0b013e318240590a","relation":{},"ISSN":["0147-5185"],"issn-type":[{"value":"0147-5185","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}