{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T20:37:17Z","timestamp":1791146237511,"version":"4.1.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1097\/pas.0b013e318258f03b","type":"journal-article","created":{"date-parts":[[2012,7,13]],"date-time":"2012-07-13T00:15:55Z","timestamp":1342138555000},"page":"1222-1227","source":"Crossref","is-referenced-by-count":116,"title":["Pathologic Characteristics of NUT Midline Carcinoma Arising in the Mediastinum"],"prefix":"10.1097","volume":"36","author":[{"given":"Andrew G.","family":"Evans","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher A.","family":"French","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Cameron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher D. M.","family":"Fletcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Jackman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher S.","family":"Lathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynette M.","family":"Sholl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-14-20210131","first-page":"508","article-title":"The cytologic features of NUT midline carcinoma.","volume":"117","author":"Bellizzi","year":"2009","journal-title":"Cancer"},{"key":"R2-14-20210131","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.cell.2011.08.017","article-title":"BET bromodomain inhibition as a therapeutic strategy to target c-Myc.","volume":"146","author":"Delmore","year":"2011","journal-title":"Cell"},{"key":"R3-14-20210131","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1056\/NEJM200104053441401","article-title":"Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.","volume":"344","author":"Druker","year":"2001","journal-title":"N Engl J Med"},{"key":"R4-14-20210131","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1038\/nature09504","article-title":"Selective inhibition of BET bromodomains.","volume":"468","author":"Filippakopoulos","year":"2010","journal-title":"Nature"},{"key":"R5-14-20210131","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1146\/annurev-pathol-011811-132438","article-title":"Pathogenesis of NUT midline carcinoma.","volume":"7","author":"French","year":"2012","journal-title":"Annu Rev Pathol"},{"key":"R6-14-20210131","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1136\/jcp.2007.052902","article-title":"Demystified molecular pathology of NUT midline carcinomas.","volume":"63","author":"French","year":"2010","journal-title":"J Clin Pathol"},{"key":"R7-14-20210131","doi-asserted-by":"crossref","first-page":"4135","DOI":"10.1200\/JCO.2004.02.107","article-title":"Midline carcinoma of children and young adults with NUT rearrangement.","volume":"22","author":"French","year":"2004","journal-title":"J Clin Oncol"},{"key":"R8-14-20210131","first-page":"304","article-title":"BRD4-NUT fusion oncogene: a novel mechanism in aggressive carcinoma.","volume":"63","author":"French","year":"2003","journal-title":"Cancer Res"},{"key":"R9-14-20210131","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1038\/sj.onc.1210852","article-title":"BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells.","volume":"27","author":"French","year":"2008","journal-title":"Oncogene"},{"key":"R10-14-20210131","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1097\/PAS.0b013e318198d666","article-title":"Diagnosis of NUT midline carcinoma using a NUT-specific monoclonal antibody.","volume":"33","author":"Haack","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"R11-14-20210131","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1097\/00043426-199124000-00011","article-title":"Intrathoracic carcinoma in an 11-year-old girl showing a translocation t(15;19).","volume":"13","author":"Kees","year":"1991","journal-title":"Am J Pediatr Hematol Oncol"},{"key":"R12-14-20210131","first-page":"3327","article-title":"Novel t(15;19)(q15;p13) chromosome abnormality in a thymic carcinoma.","volume":"51","author":"Kubonishi","year":"1991","journal-title":"Cancer Res"},{"key":"R13-14-20210131","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1056\/NEJMoa1006448","article-title":"Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.","volume":"363","author":"Kwak","year":"2010","journal-title":"N Engl J Med"},{"key":"R14-14-20210131","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1002\/1097-0142(19931001)72:7<2273::AID-CNCR2820720735>3.0.CO;2-U","article-title":"Disseminated mediastinal carcinoma with chromosomal translocation (15;19). A distinctive clinicopathologic syndrome.","volume":"72","author":"Lee","year":"1993","journal-title":"Cancer"},{"key":"R15-14-20210131","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.1017\/S1462399411001992","article-title":"Bromodomains as therapeutic targets.","volume":"13","author":"Muller","year":"2011","journal-title":"Expert Rev Mol Med"},{"key":"R16-14-20210131","doi-asserted-by":"crossref","first-page":"2686","DOI":"10.1158\/0008-5472.CAN-10-3513","article-title":"Differentiation of NUT midline carcinoma by epigenomic reprogramming.","volume":"71","author":"Schwartz","year":"2011","journal-title":"Cancer Res"},{"key":"R17-14-20210131","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s12105-010-0235-x","article-title":"A review of NUT midline carcinoma.","volume":"5","author":"Stelow","year":"2011","journal-title":"Head Neck Pathol"},{"key":"R18-14-20210131","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1097\/PAS.0b013e31815a3900","article-title":"NUT rearrangement in undifferentiated carcinomas of the upper aerodigestive tract.","volume":"32","author":"Stelow","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"R19-14-20210131","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1097\/PAP.0b013e31819923e4","article-title":"Carcinomas of the upper aerodigestive tract with rearrangement of the nuclear protein of the testis (NUT) gene (NUT midline carcinomas).","volume":"16","author":"Stelow","year":"2009","journal-title":"Adv Anat Pathol"},{"key":"R20-14-20210131","doi-asserted-by":"crossref","first-page":"27663","DOI":"10.1074\/jbc.M111.246975","article-title":"Perturbation of BRD4 protein function by BRD4-NUT protein abrogates cellular differentiation in NUT midline carcinoma.","volume":"286","author":"Yan","year":"2011","journal-title":"J Biol Chem"}],"container-title":["American Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/PAS.0b013e318258f03b","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T04:57:20Z","timestamp":1620968240000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00000478-201208000-00014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/pas.0b013e318258f03b","relation":{},"ISSN":["0147-5185"],"issn-type":[{"value":"0147-5185","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}