{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:20:15Z","timestamp":1761513615214},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Despite the publication of a number of case reports since the 1950s, physician awareness of the unique relationship between cat scratch disease (CSD) and acute encephalopathy remains limited. This report alerts emergency medicine physicians to include CSD encephalopathy (CSDE) in the differential diagnosis when a previously healthy child presents with status epilepticus. Prompt recognition of this relationship impacts the selection of initial diagnostic studies and antibiotic choices and permits reliable insight into prognosis. The 2 cases are from different eras and demonstrate the significant diagnostic advances in the past 3 decades for<jats:italic toggle=\"yes\">Bartonella henselae<\/jats:italic>infection. Both children were treated with antibiotics, and both had resolution of all neurological symptoms. However, the role of antibiotics in the treatment and outcome of CSDE remains speculative. Lastly, the report suggests potential areas of investigation to address immune-mediated mechanisms in the pathogenesis of CSDE.<\/jats:p>","DOI":"10.1097\/pec.0000000000000367","type":"journal-article","created":{"date-parts":[[2015,4,8]],"date-time":"2015-04-08T15:37:52Z","timestamp":1428507472000},"page":"789-791","source":"Crossref","is-referenced-by-count":8,"title":["Status Epilepticus Due to Cat Scratch Disease"],"prefix":"10.1097","volume":"32","author":[{"given":"Angel Lorrine","family":"Schuster","sequence":"first","affiliation":[{"name":"From the *Department of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill; \u2020Departments of Emergency Medicine and Pediatric Emergency Medicine; \u2021Department of Pediatrics, Pediatric Critical Care, WakeMed Health and Hospitals, Raleigh, NC; and \u00a7Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Travis C.B.","family":"Honeycutt","sequence":"additional","affiliation":[{"name":"From the *Department of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill; \u2020Departments of Emergency Medicine and Pediatric Emergency Medicine; \u2021Department of Pediatrics, Pediatric Critical Care, WakeMed Health and Hospitals, Raleigh, NC; and \u00a7Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harvey James","family":"Hamrick","sequence":"additional","affiliation":[{"name":"From the *Department of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill; \u2020Departments of Emergency Medicine and Pediatric Emergency Medicine; \u2021Department of Pediatrics, Pediatric Critical Care, WakeMed Health and Hospitals, Raleigh, NC; and \u00a7Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"bib1-20231023","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1001\/archpedi.1991.02160010104026","article-title":"Cat-scratch disease: acute encephalopathy and other neurologic manifestations","volume":"145","year":"1991","journal-title":"Am J Dis Child"},{"key":"bib2-20231023","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1542\/peds.2007-1897","article-title":"Beyond cat scratch disease: widening the spectrum of Bartonella henselae infection","volume":"121","year":"2008","journal-title":"Pediatrics"},{"key":"bib3-20231023","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/00006454-199702000-00002","article-title":"The expanding spectrum of Bartonella infections: II. 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