{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:10:39Z","timestamp":1762866639814},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Pericarditis is a rare presentation of thyrotoxicosis associated with Graves disease. This association has not been previously described in the pediatric literature. We report a 17-year-old male patient who presented with chest pain, dyspnea, and tachycardia. He was found to have diffuse ST-segment elevation consistent with pericarditis. At presentation, he was noted to have bilateral proptosis. Abnormal thyroid function studies and an elevated thyroid-stimulating hormone receptor antibody level confirmed the diagnosis of Graves thyrotoxicosis. The patient was treated with anti-inflammatory and antithyroid agents and improved in time. We discuss previously reported cases of Graves disease\u2013associated pericarditis in adults, potential etiologies, and management strategies.<\/jats:p>","DOI":"10.1097\/pec.0000000000000439","type":"journal-article","created":{"date-parts":[[2015,7,16]],"date-time":"2015-07-16T11:28:31Z","timestamp":1437046111000},"page":"268-270","source":"Crossref","is-referenced-by-count":8,"title":["Pericarditis as the Presenting Feature of Graves Disease in a Pediatric Patient"],"prefix":"10.1097","volume":"33","author":[{"given":"Danielle","family":"Cullen","sequence":"first","affiliation":[{"name":"From the *Department of Pediatrics and \u2020Division of Pediatric Endocrinology, Department of Pediatrics, The Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Munjal","sequence":"additional","affiliation":[{"name":"From the *Department of Pediatrics and \u2020Division of Pediatric Endocrinology, Department of Pediatrics, The Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Chalal","sequence":"additional","affiliation":[{"name":"From the *Department of Pediatrics and \u2020Division of Pediatric Endocrinology, Department of Pediatrics, The Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sriram","family":"Ramgopal","sequence":"additional","affiliation":[{"name":"From the *Department of Pediatrics and \u2020Division of Pediatric Endocrinology, Department of Pediatrics, The Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emir","family":"Tas","sequence":"additional","affiliation":[{"name":"From the *Department of Pediatrics and \u2020Division of Pediatric Endocrinology, Department of Pediatrics, The Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selma","family":"Witchel","sequence":"additional","affiliation":[{"name":"From the *Department of Pediatrics and \u2020Division of Pediatric Endocrinology, Department of Pediatrics, The Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"bib1-20231023","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4158\/EP.7.1.37","article-title":"Propylthiouracil-induced perinuclear-staining antineutrophil cytoplasmic autoantibody-positive vasculitis in conjunction with pericarditis","volume":"7","year":"2001","journal-title":"Endocr Pract"},{"key":"bib2-20231023","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1093\/qjmed\/95.3.188","article-title":"Pericardial disease associated with Grave's thyrotoxicosis","volume":"95","year":"2002","journal-title":"QJM"},{"key":"bib3-20231023","doi-asserted-by":"crossref","first-page":"e865","DOI":"10.7205\/MILMED-D-12-00531","article-title":"Pericarditis, thymic hyperplasia, and Graves' thyrotoxicosis: case report and review of the literature","volume":"178","year":"2013","journal-title":"Mil Med"},{"key":"bib4-20231023","doi-asserted-by":"crossref","first-page":"e129","DOI":"10.1016\/j.ijcard.2013.12.042","article-title":"Acute pericarditis: unique comorbidity of thyrotoxic crisis with Graves' disease","volume":"171","year":"2014","journal-title":"Int J Cardiol"},{"key":"bib5-20231023","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3949\/ccjm.70.1.57","article-title":"Thyrotoxicosis and the cardiovascular system: subtle but serious effects","volume":"70","year":"2003","journal-title":"Cleve Clin J Med"},{"key":"bib6-20231023","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1056\/NEJM194111202252102","article-title":"A postoperative follow-up study of four hundred and sixty-nine thyrocardiac patients","volume":"225","year":"1941","journal-title":"N Engl J Med"},{"key":"bib7-20231023","first-page":"217","article-title":"Hyperthyroidism associated with presumptive acute pericarditis; 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