{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:25:46Z","timestamp":1759335946534},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>The aim of the study was to explore physician perceptions of the amount of fluid that demonstrates a successful \u201ctrial of fluids\u201d (adequate fluid intake) in the emergency department in children who have had insufficient fluid intake at home.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>This is a secondary analysis of a randomized placebo-controlled trial of viscous lidocaine versus placebo in children aged 6 months to 8 years with acute infectious ulcerative mouth conditions (gingivostomatitis, ulcerative pharyngitis, or hand foot and mouth disease) and poor oral fluid intake. We measured the amount of fluid ingested in 60 minutes after administration of the intervention and related physician perception of adequate intake to measured intake. Given that there was little difference in oral intake between the treatment groups, the 2 arms were pooled for this analysis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>One hundred participants were recruited (50 per treatment group), all of whom completed the 60-minute trial period. At baseline, 72% were mildly dehydrated, 21% were not dehydrated, and 5% were moderately dehydrated. The participants drank a median of 8.6 mL\/kg (interquartile range [IQR], 3.7-14). Clinicians perceived 58% of the participants to have an adequate intake within the first hour after intervention. The median consumption of those whose oral intake was deemed as adequate was 12.6 mL\/kg (IQR, 9.4\u201318.4); for those whose oral intake was not deemed adequate, the median consumption was 2.7 mL\/kg (IQR, 0.7\u20135.3) (rank sum, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>In children undergoing trial of fluids, we found that most clinicians perceived a fluid intake greater than 9 mL\/kg as adequate and lower than 5 mL\/kg as inadequate.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/pec.0000000000000464","type":"journal-article","created":{"date-parts":[[2015,7,16]],"date-time":"2015-07-16T11:28:31Z","timestamp":1437046111000},"page":"230-233","source":"Crossref","is-referenced-by-count":2,"title":["What do Clinicians Perceive as a Successful \u201cTrial of Fluids\u201d?"],"prefix":"10.1097","volume":"33","author":[{"given":"Sandy M.","family":"Hopper","sequence":"first","affiliation":[{"name":"From the *Department of Emergency Medicine, Royal Children's Hospital; \u2020Murdoch Children's Research Institute; \u2021Department of Paediatrics, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne; and \u00a7Junior Medical Staff Department, St Vincent's Hospital, Victoria, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"McCarthy","sequence":"additional","affiliation":[{"name":"From the *Department of Emergency Medicine, Royal Children's Hospital; \u2020Murdoch Children's Research Institute; \u2021Department of Paediatrics, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne; and \u00a7Junior Medical Staff Department, St Vincent's Hospital, Victoria, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chasari","family":"Tancharoen","sequence":"additional","affiliation":[{"name":"From the *Department of Emergency Medicine, Royal Children's Hospital; \u2020Murdoch Children's Research Institute; \u2021Department of Paediatrics, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne; and \u00a7Junior Medical Staff Department, St Vincent's Hospital, Victoria, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine J.","family":"Lee","sequence":"additional","affiliation":[{"name":"From the *Department of Emergency Medicine, Royal Children's Hospital; \u2020Murdoch Children's Research Institute; \u2021Department of Paediatrics, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne; and \u00a7Junior Medical Staff Department, St Vincent's Hospital, Victoria, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Orsini","sequence":"additional","affiliation":[{"name":"From the *Department of Emergency Medicine, Royal Children's Hospital; \u2020Murdoch Children's Research Institute; \u2021Department of Paediatrics, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne; and \u00a7Junior Medical Staff Department, St Vincent's Hospital, Victoria, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz E.","family":"Babl","sequence":"additional","affiliation":[{"name":"From the *Department of Emergency Medicine, Royal Children's Hospital; \u2020Murdoch Children's Research Institute; \u2021Department of Paediatrics, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne; and \u00a7Junior Medical Staff Department, St Vincent's Hospital, Victoria, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"bib3-20231023","first-page":"1","article-title":"Managing acute gastroenteritis among children: oral rehydration, maintenance, and nutritional therapy","volume":"52","year":"2003","journal-title":"MMWR Recomm Rep"},{"key":"bib5-20231023","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1542\/peds.97.3.424","article-title":"Practice parameter: the management of acute gastroenteritis in young children. American Academy of Pediatrics, Provisional Committee on Quality Improvement, Subcommittee on Acute Gastroenteritis","volume":"97","year":"1996","journal-title":"Pediatrics"},{"key":"bib10-20231023","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S0196-0644(96)70032-X","article-title":"Outpatient rapid intravenous rehydration to correct dehydration and resolve vomiting in children with acute gastroenteritis","volume":"28","year":"1996","journal-title":"Ann Emerg Med"},{"key":"bib11-20231023","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1542\/peds.109.4.566","article-title":"Comparison of nasogastric and intravenous methods of rehydration in pediatric patients with acute dehydration","volume":"109","year":"2002","journal-title":"Pediatrics"},{"key":"bib12-20231023","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/00005176-199508000-00004","article-title":"Effectiveness of nasogastric rehydration in hospitalized children with acute diarrhea","volume":"21","year":"1995","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"bib13-20231023","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1136\/bmj.303.6799.393","article-title":"Randomised controlled trial comparing oral and intravenous rehydration therapy in children with diarrhoea","volume":"303","year":"1991","journal-title":"BMJ"},{"key":"bib14-20231023","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.cpem.2010.06.007","article-title":"A practical guide to successful rehydration","volume":"11","year":"2010","journal-title":"Clin Pediatr Emerg Med"},{"key":"bib15-20231023","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.annemergmed.2013.08.022","article-title":"Topical lidocaine to improve oral intake in children with painful infectious mouth ulcers: a blinded, randomized placebo-controlled trial","volume":"63","year":"2014","journal-title":"Ann Emerg Med"},{"key":"bib16-20231023","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/1471-2431-11-106","article-title":"A double blind, randomised placebo controlled trial of topical 2% viscous lidocaine in improving oral intake in children with painful infectious mouth conditions","volume":"11","year":"2011","journal-title":"BMC Pediatr"}],"container-title":["Pediatric Emergency Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00006565-201704000-00002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T02:00:22Z","timestamp":1698026422000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00006565-201704000-00002"}},"subtitle":["A Secondary Assessment of a Randomized Controlled Trial"],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.1097\/pec.0000000000000464","relation":{},"ISSN":["1535-1815","0749-5161"],"issn-type":[{"value":"1535-1815","type":"electronic"},{"value":"0749-5161","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]}}}