{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:12:16Z","timestamp":1762866736797,"version":"build-2065373602"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>The Lemierre syndrome is characterized by an oropharyngeal infection, thrombosis of the internal jugular vein, and multiple septic metastases. <jats:italic toggle=\"yes\">Fusobacterium necrophorum<\/jats:italic> is a common cause of it. The incidence is 0.6 to 2.3 cases per million with a mortality rate of 4% to 18%. Its fast evolution and the possibility of severe complications require a high index of suspicion for its diagnosis. We present 2 infants with Lemierre syndrome. The younger case, a 6-month-old infant, was fully recovered. In the other side, and despite an aggressive therapy, an 18-month-old infant developed cerebral palsy. We also provide a short literature review with a focus on clinical presentation and differential diagnosis in order to initiate an early and adequate therapy.<\/jats:p>","DOI":"10.1097\/pec.0000000000000570","type":"journal-article","created":{"date-parts":[[2015,10,14]],"date-time":"2015-10-14T13:00:26Z","timestamp":1444827626000},"page":"490-493","source":"Crossref","is-referenced-by-count":7,"title":["Pediatric Disseminated Lemierre Syndrome in 2 Infants"],"prefix":"10.1097","volume":"33","author":[{"given":"Alberto","family":"Garc\u00eda-Salido","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Luis","family":"Unzueta-Roch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda \u00c1ngeles","family":"Garc\u00eda-Teresa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Sirvent-Cerd\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amelia","family":"Mart\u00ednez de Azagra-Garde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Casado-Flores","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"bib1-20231023","first-page":"701","article-title":"On certain septicemias due to anaerobic organisms","volume":"1","year":"1936","journal-title":"Lancet"},{"key":"bib2-20231023","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/S1473-3099(12)70089-0","article-title":"Lemierre\u2019s syndrome due to Fusobacterium necrophorum","volume":"12","year":"2012","journal-title":"Lancet Infect Dis"},{"key":"bib3-20231023","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3928\/00904481-20110117-04","article-title":"A 17-year-old adolescent with persistent sore throat","volume":"40","year":"2011","journal-title":"Pediatr Ann"},{"key":"bib4-20231023","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1128\/CMR.00011-07","article-title":"Human infection with Fusobacterium necrophorum (necrobacillosis), with a focus on Lemierre\u2019s syndrome","volume":"20","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"bib5-20231023","first-page":"942","article-title":"A persistent sore throat","volume":"39","year":"2011","journal-title":"Aust Fam Physician"},{"key":"bib6-20231023","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1097\/MLG.0b013e318093ee0e","article-title":"Lemierre syndrome: two cases and a review","volume":"117","year":"2007","journal-title":"Laryngoscope"},{"key":"bib7-20231023","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1111\/j.1469-8749.2010.03718.x","article-title":"Neurological complications in two children with Lemierre syndrome","volume":"52","year":"2010","journal-title":"Dev Med Child Neurol"},{"key":"bib8-20231023","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.amjoto.2008.09.006","article-title":"Lemierre syndrome: a pediatric case series and review of literature","volume":"31","year":"2010","journal-title":"Am J Otolaryngol"},{"key":"bib9-20231023","doi-asserted-by":"crossref","first-page":"e543","DOI":"10.1542\/peds.2005-0433","article-title":"Lemierre\u2019s and Lemierre\u2019s-like syndromes in children: survival and thromboembolic outcomes","volume":"116","year":"2005","journal-title":"Pediatrics"},{"key":"bib10-20231023","doi-asserted-by":"crossref","first-page":"844.e1","DOI":"10.1016\/j.ajem.2009.11.024","article-title":"Lemierre syndrome: no delays in management","volume":"28","year":"2010","journal-title":"Am J Emerg Med"},{"key":"bib11-20231023","first-page":"e41","article-title":"Anticoagulation for cerebral venous sinus thrombosis","volume":"43","year":"2012","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Pediatric Emergency Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00006565-201707000-00009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T02:06:11Z","timestamp":1698026771000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00006565-201707000-00009"}},"subtitle":["Not Too Young for an Ancient Disease"],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.1097\/pec.0000000000000570","relation":{},"ISSN":["1535-1815","0749-5161"],"issn-type":[{"type":"electronic","value":"1535-1815"},{"type":"print","value":"0749-5161"}],"subject":[],"published":{"date-parts":[[2017,7]]}}}