{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:47:05Z","timestamp":1761490025522},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2018,3]]},"abstract":"\n Case<\/jats:title>\n We describe a case report of a 2-year-old boy presenting to the emergency department with cyanosis and agitation. There was no suggestive history of poisoning but parents reported the presence of an aquarium at the family dinner the night before, with an aquarium cleaner beside it. Physical examination at admission revealed central cyanosis without signs of respiratory distress. Oxygen saturation measured by pulse oximetry (Spo<\/jats:sc>\n \n 2\n <\/jats:sub>) was at 80% in room air. Plasma level of methemoglobin was measured at 11.8%. After 6 hours, methemoglobin decreased spontaneously to 5% and pulse oximetry saturation reached 98% in room air. Consciousness, weakness, and behavior were concomitantly improved. Because of rapid and spontaneous improvement, no specific treatment such as methylene blue was administered. A mass spectrometry toxicological analysis was performed in a blood sample taken the day of admission. Screening procedure of pesticides based on liquid chromatography coupled with mass spectrometry identified monolinuron, a phenylurea herbicide.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n We recommend considering acquired methemoglobinemia after ingestion of industrial products and drugs in children with cyanosis, mental status alteration, and without respiratory distress symptoms.<\/jats:p>\n <\/jats:sec>","DOI":"10.1097\/pec.0000000000000745","type":"journal-article","created":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T13:56:25Z","timestamp":1464875785000},"page":"e55-e56","source":"Crossref","is-referenced-by-count":3,"title":["Methemoglobinemia Following Monolinuron Ingestion"],"prefix":"10.1097","volume":"34","author":[{"given":"Guillaume","family":"Mortamet","sequence":"first","affiliation":[{"name":"From the *Paediatric Intensive Care Unit, H\u00f4pital Necker Enfants-Malades, Assistance Publique H\u00f4pitaux de Paris, Paris; \u2020Department of Pharmacology and Toxicology, Centre Hospitalier Universitaire de Limoges, Limoges; and \u2021Department of Pharmacology, Groupe Hospitalier Paris Centre, Assistance Publique, H\u00f4pitaux de Paris, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehdi","family":"Oualha","sequence":"additional","affiliation":[{"name":"From the *Paediatric Intensive Care Unit, H\u00f4pital Necker Enfants-Malades, Assistance Publique H\u00f4pitaux de Paris, Paris; \u2020Department of Pharmacology and Toxicology, Centre Hospitalier Universitaire de Limoges, Limoges; and \u2021Department of Pharmacology, Groupe Hospitalier Paris Centre, Assistance Publique, H\u00f4pitaux de Paris, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvain","family":"Renolleau","sequence":"additional","affiliation":[{"name":"From the *Paediatric Intensive Care Unit, H\u00f4pital Necker Enfants-Malades, Assistance Publique H\u00f4pitaux de Paris, Paris; \u2020Department of Pharmacology and Toxicology, Centre Hospitalier Universitaire de Limoges, Limoges; and \u2021Department of Pharmacology, Groupe Hospitalier Paris Centre, Assistance Publique, H\u00f4pitaux de Paris, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Moesch","sequence":"additional","affiliation":[{"name":"From the *Paediatric Intensive Care Unit, H\u00f4pital Necker Enfants-Malades, Assistance Publique H\u00f4pitaux de Paris, Paris; \u2020Department of Pharmacology and Toxicology, Centre Hospitalier Universitaire de Limoges, Limoges; and \u2021Department of Pharmacology, Groupe Hospitalier Paris Centre, Assistance Publique, H\u00f4pitaux de Paris, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Marc","family":"Treluyer","sequence":"additional","affiliation":[{"name":"From the *Paediatric Intensive Care Unit, H\u00f4pital Necker Enfants-Malades, Assistance Publique H\u00f4pitaux de Paris, Paris; \u2020Department of Pharmacology and Toxicology, Centre Hospitalier Universitaire de Limoges, Limoges; and \u2021Department of Pharmacology, Groupe Hospitalier Paris Centre, Assistance Publique, H\u00f4pitaux de Paris, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"bib1-20230930","first-page":"133","article-title":"Methemoglobin physiopathology","volume":"51","year":"1981","journal-title":"Prog Clin Biol Res"},{"key":"bib2-20230930","first-page":"1055","article-title":"Methemoglobinemia: a review and recommendations for management","volume":"28","year":"2014","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"bib3-20230930","first-page":"14","article-title":"Reference values for methemoglobin concentrations in children","volume":"34","year":"2012","journal-title":"Rev Bras Hematol Hemoter"},{"key":"bib4-20230930","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1097\/01.md.0000141096.00377.3f","article-title":"Acquired methemoglobinemia: a retrospective series of 138 cases at 2 teaching hospitals","volume":"83","year":"2004","journal-title":"Medicine (Baltimore)"},{"key":"bib5-20230930","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1373\/clinchem.2004.035154","article-title":"Laboratory assessment of oxygenation in methemoglobinemia","volume":"51","year":"2005","journal-title":"Clin Chem"},{"key":"bib6-20230930","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/2052-4374-25-31","article-title":"Two cases of methemoglobinemia induced by the exposure to nitrobenzene and aniline","volume":"25","year":"2013","journal-title":"Ann Occup Environ Med"},{"key":"bib8-20230930","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3109\/15563659409000449","article-title":"Methemoglobinemia following ingestion of a monolinuron\/paraquat herbicide (Gramonol)","volume":"32","year":"1994","journal-title":"J Toxicol Clin Toxicol"},{"key":"bib9-20230930","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1136\/bmj.285.6344.812-b","article-title":"Methaemoglobinaemia due to monolinuron-not paraquat","volume":"285","year":"1982","journal-title":"Br Med J"}],"container-title":["Pediatric Emergency Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00006565-201803000-00022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T08:07:11Z","timestamp":1696061231000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00006565-201803000-00022"}},"subtitle":["A Case Report in a Child"],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1097\/pec.0000000000000745","relation":{},"ISSN":["1535-1815","0749-5161"],"issn-type":[{"value":"1535-1815","type":"electronic"},{"value":"0749-5161","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]}}}