{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T09:43:22Z","timestamp":1698140602781},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>A 21-month-old boy came to our attention because of pneumonia. His weight increased before presentation, and his blood test results showed hyponatremia (116 mEq\/L), low plasma osmolarity (241 mOsm\/L), and high urine osmolarity (435 mOsm\/L). He was treated with 0.9% sodium chloride solution and intravenous furosemide, and sodium levels rose up to 135 mEq\/L in 36 hours. No standard treatment is available for severe hyponatremia in children. The use of vaptans in pediatric patients is described in literature, but it lacks evidence about safety and effectiveness. We suggest that furosemide administration plus salt replacement is effective in restoring normal values of plasma sodium concentration in severe euvolemic and hypervolemic hyponatremia.<\/jats:p>","DOI":"10.1097\/pec.0000000000000823","type":"journal-article","created":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T13:53:14Z","timestamp":1464875594000},"page":"390-391","source":"Crossref","is-referenced-by-count":3,"title":["Treatment of Severe Hypervolemic Hyponatremia in a Child With Pneumonia"],"prefix":"10.1097","volume":"32","author":[{"given":"Teresa","family":"Genoni","sequence":"first","affiliation":[{"name":"From the Departments of *Pediatric Emergency, \u2020Pathophysiology and Transplantation, and \u2021Pediatric Surgery, Universit\u00e0 degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rossana","family":"Tenconi","sequence":"additional","affiliation":[{"name":"From the Departments of *Pediatric Emergency, \u2020Pathophysiology and Transplantation, and \u2021Pediatric Surgery, Universit\u00e0 degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Bertolozzi","sequence":"additional","affiliation":[{"name":"From the Departments of *Pediatric Emergency, \u2020Pathophysiology and Transplantation, and \u2021Pediatric Surgery, Universit\u00e0 degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuela Anna","family":"Laicini","sequence":"additional","affiliation":[{"name":"From the Departments of *Pediatric Emergency, \u2020Pathophysiology and Transplantation, and \u2021Pediatric Surgery, Universit\u00e0 degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Tardini","sequence":"additional","affiliation":[{"name":"From the Departments of *Pediatric Emergency, \u2020Pathophysiology and Transplantation, and \u2021Pediatric Surgery, Universit\u00e0 degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Vianello","sequence":"additional","affiliation":[{"name":"From the Departments of *Pediatric Emergency, \u2020Pathophysiology and Transplantation, and \u2021Pediatric Surgery, Universit\u00e0 degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernesto","family":"Leva","sequence":"additional","affiliation":[{"name":"From the Departments of *Pediatric Emergency, \u2020Pathophysiology and Transplantation, and \u2021Pediatric Surgery, Universit\u00e0 degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregorio Paolo","family":"Milani","sequence":"additional","affiliation":[{"name":"From the Departments of *Pediatric Emergency, \u2020Pathophysiology and Transplantation, and \u2021Pediatric Surgery, Universit\u00e0 degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilio Filippo","family":"Fossali","sequence":"additional","affiliation":[{"name":"From the Departments of *Pediatric Emergency, \u2020Pathophysiology and Transplantation, and \u2021Pediatric Surgery, Universit\u00e0 degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"bib2-20231023","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1056\/NEJM200005253422107","article-title":"Hyponatremia","volume":"342","year":"2000","journal-title":"N Engl J Med"},{"key":"bib3-20231023","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1159\/000086019","article-title":"Consequences of inadequate management of hyponatremia","volume":"25","year":"2005","journal-title":"Am J Nephrol"},{"key":"bib4-20231023","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.semnephrol.2009.03.002","article-title":"The treatment of hyponatremia","volume":"29","year":"2009","journal-title":"Semin 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