{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:42:28Z","timestamp":1790091748251,"version":"4.0.1"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>The aims of the study were to determine the evolution of benign acute childhood myositis in children and to assess the relationship between creatine phosphokinase (CPK) values and myoglobinuria.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Study design<\/jats:title>\n            <jats:p>A retrospective study of patients with benign acute childhood myositis seen in 2 tertiary care university-affiliated pediatric hospitals during overlapping 4-year periods.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Demographic data, historical details, clinical, and laboratory results were extracted from the charts of children younger than 16 years with a CPK greater than 3 times normal. Complications, treatments, and outcomes were recorded.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Fifty-four children were included, 43 (80%) were male, and mean age was 7.3 years (median [range], 6 [3\u201316] years), none showed abnormal neurological findings, manifested hematuria, or developed renal failure. Mean CPK level at presentation was 1872 IU\/L (range, 511\u20138086 IU\/L). None developed renal failure, and there were no adverse outcomes on follow-up.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Acute childhood myositis is a predominantly benign disease. Neurological examination is usually normal and rhabdomyolysis is rare. Although severe pathological comorbid conditions must be excluded, a complete history and examination, coupled with simple blood and urine tests, can help minimize unnecessary diagnostic investigations.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/pec.0000000000000830","type":"journal-article","created":{"date-parts":[[2016,8,19]],"date-time":"2016-08-19T21:12:40Z","timestamp":1471641160000},"page":"400-402","source":"Crossref","is-referenced-by-count":21,"title":["Outcome of Benign Acute Childhood Myositis"],"prefix":"10.1097","volume":"34","author":[{"given":"Tom","family":"Rosenberg","sequence":"first","affiliation":[{"name":"Division of Pediatric Emergency Medicine, Department of Pediatrics, Dana-Dwek Children Hospital, Sourasky Medical Center, University of Tel Aviv, Tel Aviv;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shmuel","family":"Heitner","sequence":"additional","affiliation":[{"name":"Division of Pediatric Emergency Medicine, Shaare Zedek Medical Center, Jerusalem, Israel; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Scolnik","sequence":"additional","affiliation":[{"name":"Division of Pediatric Emergency Medicine, Clinical Pharmacology Toxicology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Einav","family":"Levin Ben-Adiva","sequence":"additional","affiliation":[{"name":"Division of Pediatric Emergency Medicine, Department of Pediatrics, Dana-Dwek Children Hospital, Sourasky Medical Center, University of Tel Aviv, Tel Aviv;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayelet","family":"Rimon","sequence":"additional","affiliation":[{"name":"Division of Pediatric Emergency Medicine, Department of Pediatrics, Dana-Dwek Children Hospital, Sourasky Medical Center, University of Tel Aviv, Tel Aviv;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Glatstein","sequence":"additional","affiliation":[{"name":"Division of Pediatric Emergency Medicine, Department of Pediatrics, Dana-Dwek Children Hospital, Sourasky Medical Center, University of Tel Aviv, Tel Aviv;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"bib1-20230930","first-page":"199","article-title":"Influenza-associated myositis in children","volume":"32","year":"2004","journal-title":"Infection"},{"key":"bib2-20230930","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1503\/cmaj.090781","article-title":"A stiff-legged gait: benign acute childhood myositis","volume":"181","year":"2009","journal-title":"CMAJ"},{"key":"bib3-20230930","first-page":"182","article-title":"Unnecessary diagnostic investigations in benign acute childhood myositis: a case series report","volume":"57","year":"2012","journal-title":"Scott Med 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