{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T23:41:28Z","timestamp":1793403688512,"version":"4.5.0"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Objective<\/jats:title>\n                    <jats:p>Identifying international differences in the epidemiology of acute poisonings in children may help in improving prevention. We sought to evaluate the international epidemiological differences in acute poisonings in children presenting to emergency departments (EDs) from 8 different global regions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was an international multicenter cross-sectional prospective study including children younger than 18 years with acute poisonings presenting to 105 EDs in 20 countries was conducted. Data collection started at each ED between January and September 2013, and continued for 1 year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>During the study period, we registered 363,245 pediatric ED presentations, of which 1727 were for poisoning (0.47%; 95% confidence interval, 0.45%\u20130.50%), with a significant variation in incidence between the regions. Full data were obtained for 1688 presentations. Most poisonings (1361 [80.6%]) occurred at home with either ingestion (1504 [89.0%]) or inhalation of the toxin (126 [7.6%]). Nonintentional exposures accounted for 1157 poisonings (68.5%; mainly in South America and Eastern Mediterranean region), with therapeutic drugs (494 [42.7%]), household products (310 [26.8%]), and pesticides (59 [5.1%]) being the most common toxins. Suicide attempts accounted for 233 exposures (13.8%; mainly in the Western Pacific region and North America), with therapeutic drugs (214 [91.8%], mainly psychotropics and acetaminophen) being the most common toxins. Significant differences between regions were found in both types of poisonings. Recreational poisonings were more common in Europe and Western Pacific region. No patient died.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There are substantial epidemiological differences in acute poisonings among children in different countries and regions of the globe. International best practices need to be identified for prevention of acute poisonings in childhood.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/pec.0000000000001031","type":"journal-article","created":{"date-parts":[[2017,1,25]],"date-time":"2017-01-25T18:58:14Z","timestamp":1485370694000},"page":"50-57","source":"Crossref","is-referenced-by-count":69,"title":["International Epidemiological Differences in Acute Poisonings in Pediatric Emergency Departments"],"prefix":"10.1097","volume":"35","author":[{"given":"Santiago","family":"Mintegi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Azkunaga","sequence":"additional","affiliation":[{"name":"Pediatric Emergency Department, Cruces University Hospital, University of the Basque Country, Bilbao, Basque Country, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Prego","sequence":"additional","affiliation":[{"name":"Departamento de Emergencia Pedi\u00e1trica, Centro Hospitalario Pereira Rossell, Montevideo, Uruguay;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadeem","family":"Qureshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart R.","family":"Dalziel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunate","family":"Arana-Arri","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Unit, Cruces University Hospital, BioCruces Health Research Institute, Basque Country, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yordana","family":"Acedo","sequence":"additional","affiliation":[{"name":"Pediatric Emergency Department, Cruces University Hospital, University of the Basque Country, Bilbao, Basque Country, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorea","family":"Martinez-Indart","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Unit, Cruces University Hospital, BioCruces Health Research Institute, Basque Country, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arantza","family":"Urkaregi","sequence":"additional","affiliation":[{"name":"University of the Basque Country, Leioa, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nerea","family":"Salmon","sequence":"additional","affiliation":[{"name":"Pediatric Emergency Department, Cruces University Hospital, University of the Basque Country, Bilbao, Basque Country, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Benito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Kuppermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"bib2-20230930","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1136\/archdischild-2013-305298","article-title":"Hospital admissions for unintentional poisoning in preschool children in England; 2000\u20132011","volume":"100","year":"2015","journal-title":"Arch Dis Child"},{"key":"bib3-20230930","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1542\/peds.2007-3551","article-title":"Unintentional child poisonings treated in United States hospital emergency departments: national estimates of incident cases, population-based poisoning rates, and product involvement","volume":"122","year":"2008","journal-title":"Pediatrics"},{"key":"bib4-20230930","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.ajem.2005.05.001","article-title":"2004 Annual Report of the American Association of Poison Control Centers Toxic Exposure Surveillance System","volume":"23","year":"2005","journal-title":"Am J Emerg Med"},{"key":"bib5-20230930","doi-asserted-by":"crossref","first-page":"949","DOI":"10.3109\/15563650.2013.863906","article-title":"2012 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 30th annual report","volume":"51","year":"2013","journal-title":"Clin Toxicol (Phila)"},{"key":"bib6-20230930","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/MEJ.0b013e3283462504","article-title":"Toxicology surveillance system of the Spanish Society of Paediatric Emergencies: first-year analysis","volume":"18","year":"2011","journal-title":"Eur J Emerg Med"},{"key":"bib7-20230930","first-page":"376","article-title":"y el Grupo de Trabajo de Intoxicaciones de la Sociedad Espa\u00f1ola de Urgencias de Pediatr\u00eda. 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