{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:50:15Z","timestamp":1760147415298},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>Cerebral infarction due to minor head injury is rare. Mineralizing angiopathy is considered a predisposing factor for lenticulostriate stroke after minor closed head injury. This entity is characterized by infarction of the basal ganglia and most often occurs in young children, from infancy to 2 years of age. Symptoms usually occur immediately after the injury.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p>We present the case of a previously healthy 2-year-old female child presenting with right facial hemiparesis and aphasia, along with right arm and leg weakness that occurred immediately after a fall from the couch onto a carpeted floor. A brain computed tomography scan revealed small and linear calcifications of the basal ganglia and subcortical frontoparietal area, in the absence of signs of intracranial hemorrhage. Brain magnetic resonance imaging with stroke protocol revealed restriction of water diffusion in the left basal ganglia on diffusion-weighted imaging sequences as well as apparent diffusion coefficient sequences, suggesting an acute infarct of the left basal ganglia within the distribution of the lenticulostriate vessels. The patient was treated with aspirin and conservative management and had gradual improvement over the next few days, with full recovery of the aphasia, facial nerve function, and arm and leg mobility, within 2 months.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Some infants can present with the onset of stroke-like symptoms after minor head injuries. Presence of linear calcifications of the basal ganglia noticed on brain computed tomography in many of these patients suggests that mineralizing angiopathy may be a predisposing factor for lenticulostriate stroke after minor closed head injury in infants. Brain magnetic resonance imaging to further delineate possible cerebral infarction is indicated.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/pec.0000000000001229","type":"journal-article","created":{"date-parts":[[2017,7,4]],"date-time":"2017-07-04T16:37:01Z","timestamp":1499186221000},"page":"e233-e235","source":"Crossref","is-referenced-by-count":10,"title":["A Case of Lenticulostriate Stroke Due to Minor Closed Head Injury in a 2-Year-Old Child"],"prefix":"10.1097","volume":"34","author":[{"given":"Emin","family":"Fidan","sequence":"first","affiliation":[{"name":"Pediatric Critical Care Medicine,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana D.","family":"Cummings","sequence":"additional","affiliation":[{"name":"Child Neurology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mioara D.","family":"Manole","sequence":"additional","affiliation":[{"name":"Pediatric Emergency Medicine, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"bib2-20230930","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1126\/science.1088417","article-title":"Inflammatory blockade restores adult hippocampal neurogenesis","volume":"302","year":"2003","journal-title":"Science"},{"key":"bib3-20230930","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1016\/S0140-6736(09)61558-0","article-title":"Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study","volume":"374","year":"2009","journal-title":"Lancet"},{"key":"bib4-20230930","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1824-7288-37-2","article-title":"Basal ganglia stroke due to mild head trauma in pediatric age\u2014clinical and therapeutic management: a case report and 10 year literature review","volume":"37","year":"2011","journal-title":"Ital J Pediatr"},{"key":"bib5-20230930","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.pediatrneurol.2012.12.008","article-title":"Clinical features and risk factors of cerebral infarction after mild head trauma under 18 months of age","volume":"48","year":"2013","journal-title":"Pediatr Neurol"},{"key":"bib6-20230930","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/dmcn.12275","article-title":"Mineralizing angiopathy with infantile basal ganglia stroke after minor trauma","volume":"56","year":"2014","journal-title":"Dev Med Child Neurol"},{"key":"bib7-20230930","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1159\/000103313","article-title":"Ischemia of the internal capsule due to mild head injury in a child","volume":"43","year":"2007","journal-title":"Pediatr Neurosurg"},{"key":"bib8-20230930","first-page":"994","article-title":"Ischemic stroke following mild head injury is it the cause","volume":"43","year":"2006","journal-title":"Indian Pediatr"},{"key":"bib9-20230930","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1007\/s00381-006-0157-9","article-title":"Posttraumatic infarction in the territory supplied by the lateral lenticulostriate artery after minor head injury","volume":"22","year":"2006","journal-title":"Childs Nerv Syst"},{"key":"bib10-20230930","first-page":"415","article-title":"Posttraumatic infarction in the basal ganglia after a minor head injury in a child: case report","volume":"18","year":"2008","journal-title":"Turk Neurosurg"},{"key":"bib11-20230930","first-page":"113","article-title":"Posttraumatic isolated infarction in the territory of Heubner's and lenticulostriate arteries: case report","volume":"47","year":"2001","journal-title":"Kobe J Med Sci"},{"key":"bib12-20230930","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1136\/adc.88.3.267","article-title":"Can mild head injury cause ischaemic stroke?","volume":"88","year":"2003","journal-title":"Arch Dis Child"},{"key":"bib13-20230930","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/0720-048X(95)00607-R","article-title":"Basal ganglia infarcts with calcifications in children","volume":"20","year":"1995","journal-title":"Eur J Radiol"},{"key":"bib14-20230930","first-page":"863","article-title":"Ischemic lesions in basal ganglia in children after minor head injury","volume":"33","year":"1993","journal-title":"Neurosurgery"},{"key":"bib15-20230930","doi-asserted-by":"crossref","first-page":"261","DOI":"10.3171\/jns.1985.62.2.0261","article-title":"The perforating branches of the middle cerebral artery. 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