{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:11:20Z","timestamp":1786119080096,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Herpes simplex virus (HSV) is rarely the cause of pneumonia in immunocompetent patients. We describe a previously healthy child, with no evidence of an immunodeficiency, who presented to the emergency department with severe pneumonia, wheezing, and pleural effusions with a history of orolabial HSV infection. On admission, he was started on antibiotics and systemic corticosteroids but continued to deteriorate. Oral lesions, blood, and pleural fluid tested positive for HSV, and improvement was achieved only after the addition of acyclovir and discontinuation of steroids. We suggest that steroids should be used with caution in patients presenting with lower respiratory tract symptoms and herpetic oral lesions.<\/jats:p>","DOI":"10.1097\/pec.0000000000001519","type":"journal-article","created":{"date-parts":[[2018,5,24]],"date-time":"2018-05-24T14:23:05Z","timestamp":1527171785000},"page":"e735-e736","source":"Crossref","is-referenced-by-count":3,"title":["Herpes Simplex Virus Pneumonia in an Immunocompetent Child on Corticosteroids for Acute Wheezing"],"prefix":"10.1097","volume":"36","author":[{"given":"Naama","family":"Pines","sequence":"first","affiliation":[{"name":"Department of Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reuven","family":"Tsabari","sequence":"additional","affiliation":[{"name":"Pediatric Pulmonary and Sleep Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eitan","family":"Kerem","sequence":"additional","affiliation":[{"name":"Pediatric Pulmonary and Sleep Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Reiter","sequence":"additional","affiliation":[{"name":"Pediatric Pulmonary and Sleep Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2018,5,24]]},"reference":[{"key":"bib1-20231002","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1056\/NEJMoa1405870","article-title":"Community-acquired pneumonia requiring hospitalization among U.S. children","volume":"372","year":"2015","journal-title":"N Engl J Med"},{"key":"bib2-20231002","first-page":"37","article-title":"Severe adenovirus infection in 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