{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T09:19:12Z","timestamp":1696065552605},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Spontaneous colon perforation is a known complication of vascular Ehlers-Danlos syndrome (vEDS) in the pediatric age group. The diagnosis of vEDS is often missed until the child presents to the pediatric emergency room with a complication like spontaneous arterial or colon rupture. These patients require immediate imaging and surgical attention to decrease morbidity and mortality. We present the case of a 9-year-old boy with abdominal pain and retching. An abdominal computed tomography revealed free air under the diaphragm, and surgical exploration showed perforation of the sigmoid colon. Ultimately, he was diagnosed with vEDS. We review the literature and discuss the clinical presentation, diagnosis, and life-threatening crises associated with vEDS.<\/jats:p>","DOI":"10.1097\/pec.0000000000001573","type":"journal-article","created":{"date-parts":[[2018,10,22]],"date-time":"2018-10-22T21:20:26Z","timestamp":1540243226000},"page":"e245-e247","source":"Crossref","is-referenced-by-count":0,"title":["Bent Out of Shape"],"prefix":"10.1097","volume":"35","author":[{"given":"Praneetha","family":"Chaganti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer H.","family":"Chao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2018,10,20]]},"reference":[{"key":"bib2-20230930","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1159\/000363373","article-title":"Spontaneous colon perforations associated with a vascular type of Ehlers-Danlos syndrome","volume":"8","year":"2014","journal-title":"Case Rep Gastroenterol"},{"key":"bib3-20230930","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/ajmg.c.31553","article-title":"Diagnosis, natural history, and management in vascular Ehlers-Danlos syndrome","volume":"175","year":"2017","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"bib5-20230930","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.adnc.2005.09.006","article-title":"The clinical presentation of Ehlers-Danlos syndrome","volume":"5","year":"2005","journal-title":"Adv Neonatal Care"},{"key":"bib6-20230930","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1750-1172-2-32","article-title":"Ehlers-Danlos syndrome type IV","volume":"2","year":"2007","journal-title":"Orphanet J Rare Dis"},{"key":"bib7-20230930","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.1016\/j.jpedsurg.2006.04.009","article-title":"A novel mutation in the vascular Ehlers-Danlos Syndrome: a case presenting with colonic perforations","volume":"41","year":"2006","journal-title":"J Pediatr Surg"},{"key":"bib8-20230930","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/0022-3468(90)90759-3","article-title":"Perforation of the colon in a 15-year-old girl with Ehlers-Danlos syndrome type IV","volume":"25","year":"1990","journal-title":"J Pediatr Surg"}],"container-title":["Pediatric Emergency Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/PEC.0000000000001573","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T08:28:48Z","timestamp":1696062528000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/PEC.0000000000001573"}},"subtitle":["A Case of Abdominal Pain"],"short-title":[],"issued":{"date-parts":[[2018,10,20]]},"references-count":6,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1097\/pec.0000000000001573","relation":{},"ISSN":["1535-1815","0749-5161"],"issn-type":[{"value":"1535-1815","type":"electronic"},{"value":"0749-5161","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10,20]]}}}