{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T12:25:15Z","timestamp":1794313515600,"version":"4.9.0"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec>\n            <jats:title>Objectives<\/jats:title>\n            <jats:p>Serious bacterial infections (SBIs) in young infants can present with fever or hypothermia. There are substantial data on fever as a presentation for SBI that help to inform the clinical approach. In contrast, data on hypothermia are lacking, thus leaving clinicians without guidance. We aimed to describe the workup and findings, specifically the occurrence, of SBIs in infants younger than 60 days of life with hypothermia.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>We reviewed the medical records of infants younger than 60 days of life with rectal temperature of less than 36.5\u00b0C upon arrival to a children's hospital emergency department between January 2013 and December 2014. Comparisons were made between those who were found to have an SBI and those without. Serious bacterial infection was defined as bacteremia, bacterial meningitis, pneumonia, or urinary tract infection (UTI).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>From the 414 patients identified, 104 (25%) underwent a sepsis evaluation of blood, urine, and\/or cerebrospinal fluid culture. Serious bacterial infections were identified in 9 patients: 4 with UTI, 1 with pneumonia, 2 with bacteremia, 1 with pneumonia and UTI, and 1 with meningitis and bacteremia. Compared with patients with negative cultures, patients with SBI were older and had elevated absolute band counts and elevated immature-to-total neutrophil ratio.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Approximately a quarter of infants younger than 60 days with hypothermia were evaluated for SBI. Serious bacterial infection was identified in 9% of evaluated infants (2% of all hypothermic infants). Hypothermia can be a presenting sign of SBI.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/pec.0000000000001674","type":"journal-article","created":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T01:22:39Z","timestamp":1542158559000},"page":"e449-e455","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":32,"title":["Hypothermia in Young Infants"],"prefix":"10.1097","volume":"37","author":[{"given":"Michelle C.","family":"Perry","sequence":"first","affiliation":[{"name":"Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan K.","family":"Yaeger","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Lehigh Valley Health Network, Allentown, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Noorbakhsh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea T.","family":"Cruz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine, Houston, TX."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert W.","family":"Hickey","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2018,11,13]]},"reference":[{"key":"bib1-20250504","first-page":"e356","article-title":"Using the Rochester criteria to evaluate infantile fever is more effective in males than females","volume":"105","year":"2016","journal-title":"Acta Paediatr"},{"key":"bib2-20250504","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1136\/adc.58.2.143","article-title":"Infection in neonatal hypothermia","volume":"58","year":"1983","journal-title":"Arch Dis Child"},{"key":"bib3-20250504","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/PEC.0b013e318191db54","article-title":"Occurrence of serious bacterial infection in infants aged 60 days or younger with an apparent life-threatening event","volume":"25","year":"2009","journal-title":"Pediatr Emerg Care"},{"key":"bib4-20250504","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1097\/01.PCC.0000149131.72248.E6","article-title":"International Consensus Conference on Pediatric S. 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