{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T12:58:09Z","timestamp":1762001889898},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Necrotizing soft tissue infections are a serious medical emergency that involve necrosis within the soft tissue space including the dermis, subcutaneous tissue, superficial fascia, deep fascia, and muscle. Inciting factors include recent varicella infection, omphalitis, trauma, intramuscular injections, perianal trauma, and surgery. Unlike adult cases, children presenting with necrotizing soft tissue infections are more likely to be immunocompetent and without underlying chronic illnesses. Although rare in children, familiarity with the clinical manifestations of necrotizing soft tissue infections is essential for early diagnosis and surgical debridement, as significant mortality is associated with advanced disease.<\/jats:p>","DOI":"10.1097\/pec.0000000000001888","type":"journal-article","created":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T22:22:45Z","timestamp":1562883765000},"page":"e138-e140","source":"Crossref","is-referenced-by-count":1,"title":["Otherwise Healthy 15-Month-Old With Rapid-Onset Soft Tissue Swelling"],"prefix":"10.1097","volume":"35","author":[{"given":"Julie Jelaine","family":"Anderson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Avendano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Kaila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2019,7,13]]},"reference":[{"key":"bib1-20230930","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1086\/511638","article-title":"Necrotizing soft-tissue infection: diagnosis and management","volume":"44","year":"2007","journal-title":"Clin Infect Dis"},{"key":"bib2-20230930","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1097\/00007611-199711000-00001","article-title":"Necrotizing fasciitis: improved survival with early recognition by tissue biopsy and aggressive surgical treatment","volume":"90","year":"1997","journal-title":"South Med J"},{"key":"bib3-20230930","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jamcollsurg.2008.10.032","article-title":"Necrotizing fasciitis: current concepts and review of the literature","volume":"208","year":"2009","journal-title":"J Am Coll Surg"},{"key":"bib4-20230930","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.2106\/00004623-200308000-00005","article-title":"Necrotizing fasciitis: clinical presentation, microbiology, and determinants of mortality","volume":"85","year":"2003","journal-title":"J Bone Joint Surg Am"},{"key":"bib5-20230930","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1016\/j.jpedsurg.2007.07.018","article-title":"Necrotizing fasciitis in children: diagnostic and therapeutic aspects","volume":"42","year":"2007","journal-title":"J Pediatr Surg"},{"key":"bib6-20230930","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/S0022-3468(96)90104-9","article-title":"Necrotizing fasciitis in children: prompt recognition and aggressive therapy improve survival","volume":"31","year":"1996","journal-title":"J Pediatr Surg"},{"key":"bib7-20230930","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1097\/01.CCM.0000129486.35458.7D","article-title":"The LRINEC (laboratory risk indicator for necrotizing fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections","volume":"32","year":"2004","journal-title":"Crit Care Med"},{"key":"bib8-20230930","first-page":"e210","article-title":"Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America","volume":"59","year":"2014","journal-title":"Clin Infect Dis"}],"container-title":["Pediatric Emergency Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00006565-201908000-00015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T08:20:59Z","timestamp":1696062059000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00006565-201908000-00015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,13]]},"references-count":8,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1097\/pec.0000000000001888","relation":{},"ISSN":["1535-1815","0749-5161"],"issn-type":[{"value":"1535-1815","type":"electronic"},{"value":"0749-5161","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7,13]]}}}