{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T09:46:13Z","timestamp":1794563173642,"version":"4.9.1"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Acute lymphoblastic leukemia (ALL) in a neonate can have a similar clinical appearance to other serious pathology and should be considered in the ill-appearing infant. We present the case of a 24-hour-old male infant born to a mother with limited prenatal care who was brought to the pediatric emergency department with a rash and decreased movement. His initial white blood cell count was 822 \u00d7 10<jats:sup>9<\/jats:sup> cells\/L. Cytogenetics showed a complex t (9;19;11) translocation, indicating a diagnosis of neonatal ALL. Given the morbidity and mortality rate among infants with neonatal ALL, his parents elected not to pursue cancer-directed therapy in favor of symptomatic care.<\/jats:p>","DOI":"10.1097\/pec.0000000000001956","type":"journal-article","created":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T18:26:51Z","timestamp":1580754411000},"page":"e102-e103","source":"Crossref","is-referenced-by-count":1,"title":["Neonatal Acute Lymphoblastic Leukemia"],"prefix":"10.1097","volume":"36","author":[{"given":"Rachel","family":"Oliver","sequence":"first","affiliation":[{"name":"Texas A&M Health Science Center, Bryan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew L.","family":"Juergens","sequence":"additional","affiliation":[{"name":"Baylor Scott & White Health \u2013 Temple, Temple, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek","family":"Hatch","sequence":"additional","affiliation":[{"name":"United States Air Force Academy, El Paso County, CO."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominic","family":"Lucia","sequence":"additional","affiliation":[{"name":"Baylor Scott & White Health \u2013 Temple, Temple, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"DeLario","sequence":"additional","affiliation":[{"name":"Baylor Scott & White Health \u2013 Temple, Temple, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"bib1-20231107","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.siny.2012.03.003","article-title":"Diagnosis and management of neonatal leukaemia","volume":"17","year":"2012","journal-title":"Semin Fetal Neonatal Med"},{"key":"bib2-20231107","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1097\/00043426-200305000-00002","article-title":"Fetal and neonatal leukemia","volume":"25","year":"2003","journal-title":"J Pediatr Hematol Oncol"},{"key":"bib3-20231107","doi-asserted-by":"crossref","first-page":"151","DOI":"10.3109\/08880019609030805","article-title":"Transient acute monoblastic leukemia with reciprocal (8;16) (p11;p13) translocation","volume":"13","year":"1996","journal-title":"Pediatr Hematol Oncol"},{"key":"bib4-20231107","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.pedneo.2013.06.009","article-title":"Juvenile myelomonocytic leukemia in a premature neonate mimicking neonatal sepsis","volume":"57","year":"2016","journal-title":"Pediatr Neonatol"},{"key":"bib5-20231107","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/bjh.12041","article-title":"Transient myeloproliferative disorder in children with Down syndrome: clarity to this enigmatic disorder","volume":"159","year":"2012","journal-title":"Br J Haematol"},{"key":"bib6-20231107","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1634\/theoncologist.4-3-225","article-title":"Leukemia in infants","volume":"4","year":"1999","journal-title":"Oncologist"},{"key":"bib7-20231107","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1002\/pbc.20599","article-title":"Features and outcome of neonatal leukemia in Japan: experience of the Japan infant leukemia study group","volume":"47","year":"2006","journal-title":"Pediatr Blood Cancer"},{"key":"bib8-20231107","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1046\/j.1365-2141.2002.03459.x","article-title":"Congenital leukaemia: the Dutch experience and review of the literature","volume":"117","year":"2002","journal-title":"Br J Haematol"},{"key":"bib9-20231107","doi-asserted-by":"crossref","first-page":"e131","DOI":"10.1016\/j.jemermed.2015.01.011","article-title":"Congenital leukemia presenting as fever in a neonate","volume":"48","year":"2015","journal-title":"J Emerg Med"},{"issue":"5 pt 1","key":"bib10-20231107","first-page":"673","article-title":"Purpura in infants and children","volume":"37","year":"1999","journal-title":"J Am Acad Dermatol"}],"container-title":["Pediatric Emergency Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/PEC.0000000000001956","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T21:04:25Z","timestamp":1699391065000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/PEC.0000000000001956"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.1097\/pec.0000000000001956","relation":{},"ISSN":["1535-1815","0749-5161"],"issn-type":[{"value":"1535-1815","type":"electronic"},{"value":"0749-5161","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]}}}