{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T23:07:21Z","timestamp":1770419241182,"version":"3.49.0"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the clinical presentation of intussusception among children younger and older than 24 months of age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design\/Methods<\/jats:title><jats:p>We performed a retrospective cross-sectional cohort study of children treated in the emergency department, aged 1 month to 6 years, who had an abdominal ultrasound to evaluate for intussusception over a 5-year period. After stratifying by an age cut-point of 24 months, univariate and multivariate analyses were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One thousand two hundred fifty-eight cases of suspected intussusception were studied; median age was 1.7 years (interquartile range, 0.8, 2.9 years), and 37% were female. Intussusception was identified in 176 children (14%); 153 (87%) were ileocolic, and 23 were ileoileal. Abdominal pain (odds ratio, 4.0; 95% confidence interval [CI], 1.5\u201310.5), emesis (OR, 3.5; 95% CI, 1.8\u20136.7), bilious emesis (OR, 2.9; 95% CI, 1.5\u20135.7), lethargy (OR, 2.3; 95% CI, 1.3\u20135.7), rectal bleeding (OR, 2.8; 95% CI, 1.4\u20135.7), and irritability (OR, 0.4; 95% CI, 0.2\u20130.8) were found to be predictors in those younger than 24 months. In children older than 24 months, male sex was the only predictor identified (OR, 2.0; 95% CI, 1.1\u20133.7). In cases where abdominal radiographs were obtained (n = 1212), any abnormality on abdominal radiograph was found to be predictive in both age groups (OR, 7.8; 95% CI, 3.8\u201325.7; and OR, 3.1; 95% CI, 1.8\u20135.2, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Intussusception presents differently in children younger than 24 months compared with older children. \u201cTraditional\u201d clinical predictors of intussusception should be interpreted with caution when assessing children older than 2 years.<\/jats:p><\/jats:sec>","DOI":"10.1097\/pec.0000000000002179","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T06:00:11Z","timestamp":1594620011000},"page":"372-377","source":"Crossref","is-referenced-by-count":8,"title":["Variation in the Presentation of Intussusception by Age"],"prefix":"10.1097","volume":"36","author":[{"given":"Amir A.","family":"Kimia","sequence":"first","affiliation":[{"name":"Boston Children's Hospital, Boston, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter N.","family":"Hadar","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scotty","family":"Williams","sequence":"additional","affiliation":[{"name":"Boston Children's Hospital, Boston, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Assaf","family":"Landschaft","sequence":"additional","affiliation":[{"name":"Boston Children's Hospital, Boston, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael C.","family":"Monuteaux","sequence":"additional","affiliation":[{"name":"Boston Children's Hospital, Boston, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard G.","family":"Bachur","sequence":"additional","affiliation":[{"name":"Boston Children's Hospital, Boston, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2020,7,13]]},"reference":[{"key":"bib1-20230930","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1097\/00005176-200411000-00012","article-title":"Clinical case definition for the diagnosis of acute intussusception","volume":"39","year":"2004","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"bib2-20230930","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1177\/000992280404300405","article-title":"The diagnosis of intussusception","volume":"43","year":"2004","journal-title":"Clin Pediatr (Phila)"},{"key":"bib3-20230930","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1742-6723.2007.00923.x","article-title":"Paediatric intussusception: epidemiology and outcome","volume":"19","year":"2007","journal-title":"Emerg Med 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