{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:19:00Z","timestamp":1767651540496,"version":"3.40.5"},"reference-count":41,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n            <jats:title>Objectives<\/jats:title>\n            <jats:p>Mercury exposure is common and can be toxic, especially in children. Children are often drawn to elemental mercury because of its density, color, and proclivity to form beads.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>We present data on 49 children with mercury intoxication (MI) and 60 children with mercury exposure from Turkey.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The most common source of mercury was broken thermometer in schools. Inhaling mercury vapor was the most common route of exposure. The median exposure time was 6 (6\u201316) hours in the MI group, and the time to 1st symptoms was 10 (0\u201324) hours. In the MI group, the median blood mercury level was 21 \u03bcg\/L (13\u201332.3), the median spot urine mercury level was 40 \u03bcg\/L (7.66\u201378), and the median 24-hour urine mercury level was 25.8 \u03bcg\/L (11\u201364). The most common symptoms in patients with MI were malaise, muscle pain, muscle cramps, abdominal pain, nausea, headache, and decreased appetite. The patients were treated with n-acetyl cysteine, 2,3-dimercaptopropane sulfonic acid, D-penicillamine, and meso 2,3-dimercaptosuccinic acid. A positive correlation was found between exposure time and urinary mercury level in the MI group (r = 0.793, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001). A positive moderate correlation was found between exposure time and blood level in the mercury exposure group (r = 0.535, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.00). The neurological and systemic examinations of patients were all normal at the 1st follow-up visit 1 month after discharge.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Diagnosis, removal of the exposure source, and use of chelation therapy can result in complete resolution of the signs and symptoms of MI.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/pec.0000000000002834","type":"journal-article","created":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T16:01:46Z","timestamp":1662480106000},"page":"481-488","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Characteristics, Treatment, and Prognosis of Elemental Mercury Intoxication in Children"],"prefix":"10.1097","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4293-910X","authenticated-orcid":false,"given":"Deniz","family":"G\u00fcven","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Health Sciences, Ankara Atat\u00fcrk Sanatorium Training and Research Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0097-7586","authenticated-orcid":false,"given":"\u0130mran","family":"\u00d6zbek","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Ankara Gazi Mustafa Kemal Occupational and Environmental Diseases Hospital, Ankara, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2022,9,2]]},"reference":[{"key":"bib1-20250504","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1542\/peds.108.1.197","article-title":"Technical report: mercury in the environment: implications for pediatricians","volume":"108","year":"2001","journal-title":"Pediatrics"},{"key":"bib2-20250504","doi-asserted-by":"crossref","first-page":"652","DOI":"10.3109\/08958378.2012.708677","article-title":"Mercury vapor inhalation and poisoning of a family","volume":"24","year":"2012","journal-title":"Inhal Toxicol"},{"key":"bib3-20250504","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/s00431-013-1970-2","article-title":"Acute mercury poisoning among children in two provinces of Turkey","volume":"172","year":"2013","journal-title":"Eur J Pediatr"},{"key":"bib4-20250504","first-page":"37","article-title":"Liquid mercury: a poisonous plaything","volume":"19","year":"2002","journal-title":"Comtemp Pediatr"},{"key":"bib5-20250504","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1289\/ehp.02110129","article-title":"Public health consequences of mercury spills: hazardous substances emergency events surveillance system, 1993\u20131998","volume":"110","year":"2002","journal-title":"Environ Health Perspect"},{"key":"bib7-20250504","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s00431-003-1389-2","article-title":"Mercury intoxication resulting from school barometers in three unrelated adolescents","volume":"163","year":"2004","journal-title":"Eur J Pediatr"},{"key":"bib8-20250504","first-page":"186","article-title":"Mercury exposure and children's health","volume":"40","year":"2010","journal-title":"Curr Probl Pediatr Adolesc Health Care"},{"key":"bib10-20250504","first-page":"366","article-title":"Mercury poisoning after spillage at home from a sphygmomanometer on loan from hospital [published correction appears in BMJ 1999 Sep 4;319(7210):608]","volume":"319","year":"1999","journal-title":"BMJ"},{"key":"bib11-20250504","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/BF01055557","article-title":"Indoor air mercury concentrations following application of interior latex paint","volume":"21","year":"1991","journal-title":"Arch Environ Contam Toxicol"},{"key":"bib12-20250504","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1080\/00984109708984016","article-title":"Mercury content in skin-lightening creams and potential hazards to the health of Saudi women","volume":"51","year":"1997","journal-title":"J Toxicol Environ Health"},{"key":"bib13-20250504","doi-asserted-by":"crossref","first-page":"2868","DOI":"10.1001\/jama.292.23.2868","article-title":"Heavy metal content of ayurvedic herbal medicine products","volume":"292","year":"2004","journal-title":"JAMA"},{"key":"bib14-20250504","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1579\/0044-7447(2007)36[3:MEAHEI]2.0.CO;2","article-title":"Methylmercury exposure and health effects in humans: a worldwide concern","volume":"36","year":"2007","journal-title":"Ambio"},{"key":"bib15-20250504","first-page":"72","article-title":"Acute mercurial poisoning by inhalation of metallic vapour in an infant","volume":"58","year":"1948","journal-title":"Can Med Assoc J"},{"issue":"4 Part 1","key":"bib16-20250504","first-page":"675","article-title":"Acute poisoning associated with inhalation of mercury vapor; report of four cases","volume":"22","year":"1958","journal-title":"Pediatrics"},{"key":"bib17-20250504","first-page":"1","article-title":"Elemental mercury poisoning in a family of seven [published correction appears in fam community health 2002 Apr;25(1):x]","volume":"24","year":"2002","journal-title":"Fam Community Health"},{"key":"bib18-20250504","doi-asserted-by":"crossref","first-page":"886","DOI":"10.3109\/15563650.2011.626425","article-title":"Inorganic mercury poisoning associated with skin-lightening cosmetic products","volume":"49","year":"2011","journal-title":"Clin Toxicol (Phila)"},{"key":"bib19-20250504","doi-asserted-by":"crossref","first-page":"467","DOI":"10.5152\/balkanmedj.2016.15197","article-title":"A 3 year-old male child ingested approximately 750 grams of elemental mercury","volume":"33","year":"2016","journal-title":"Balkan Med J"},{"key":"bib20-20250504","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1097\/PEC.0b013e3182494ed0","article-title":"Case series of mercury toxicity among children in a hot, closed environment","volume":"28","year":"2012","journal-title":"Pediatr Emerg Care"},{"key":"bib21-20250504","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1006\/taap.1998.8400","article-title":"The absorption, blood levels, and excretion of mercury after a single dose of mercury vapor in humans","volume":"150","year":"1998","journal-title":"Toxicol Appl Pharmacol"},{"key":"bib22-20250504","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/00006565-200204000-00010","article-title":"Elemental mercury as an attractive nuisance: multiple exposures from a pilfered school supply with severe consequences","volume":"18","year":"2002","journal-title":"Pediatr Emerg Care"},{"key":"bib23-20250504","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.cca.2016.12.019","article-title":"Acute mercury vapor poisoning in a 3-month-old infant: a case report","volume":"465","year":"2017","journal-title":"Clin Chim Acta"},{"key":"bib24-20250504","first-page":"000632","article-title":"Chronic mercury intoxication masquerading as systemic disease: a case report and review of the literature","volume":"4","year":"2017","journal-title":"Eur J Case Rep Intern Med"},{"key":"bib25-20250504","first-page":"13030\/qt6444r7nc","article-title":"Mercury toxicity presenting as acrodynia and a papulovesicular eruption in a 5-year-old girl","volume":"22","year":"2016","journal-title":"Dermatol Online J"},{"key":"bib26-20250504","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1136\/adc.80.6.556","article-title":"Mercury intoxication presenting with hypertension and tachycardia","volume":"80","year":"1999","journal-title":"Arch Dis Child"},{"key":"bib27-20250504","doi-asserted-by":"crossref","first-page":"E34","DOI":"10.1542\/peds.105.3.e34","article-title":"Mercury intoxication and arterial hypertension: report of two patients and review of the literature","volume":"105","year":"2000","journal-title":"Pediatrics"},{"key":"bib28-20250504","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s00431-009-1073-2","article-title":"Being alive after a severe inorganic mercury intoxication","volume":"169","year":"2010","journal-title":"Eur J Pediatr"},{"issue":"8\u20139","key":"bib29-20250504","first-page":"580","article-title":"Mercury as a cause of fulminant hepatic failure in a child: case report and literature review","volume":"35","year":"2011","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"bib30-20250504","doi-asserted-by":"crossref","first-page":"301","DOI":"10.4103\/0971-4065.114485","article-title":"Acute renal failure secondary to ingestion of ayurvedic medicine containing mercury","volume":"23","year":"2013","journal-title":"Indian J Nephrol"},{"key":"bib31-20250504","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/2052-4374-25-18","article-title":"Four cases of abnormal neuropsychological findings in children with high blood methylmercury concentrations","volume":"25","year":"2013","journal-title":"Ann Occup Environ Med"},{"key":"bib32-20250504","doi-asserted-by":"crossref","first-page":"17","DOI":"10.4103\/0019-5278.64610","article-title":"Chronic mercury poisoning: report of two siblings","volume":"14","year":"2010","journal-title":"Indian J Occup Environ Med"},{"key":"bib33-20250504","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1007\/s00296-020-04589-2","article-title":"Mercury intoxication resembling pediatric rheumatic diseases: case series and literature review","volume":"40","year":"2020","journal-title":"Rheumatol Int"},{"key":"bib34-20250504","doi-asserted-by":"crossref","first-page":"25","DOI":"10.5696\/2156-9614-5-9.25","article-title":"Effect of mercury exposure on renal function and hematological parameters among artisanal and small-scale gold miners at Sekotong, West Lombok, Indonesia","volume":"5","year":"2015","journal-title":"J Health Pollut"},{"key":"bib35-20250504","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.4269\/ajtmh.17-0269","article-title":"Hair mercury level is associated with anemia and micronutrient status in children living near artisanal and small-scale gold mining in the Peruvian Amazon","volume":"97","year":"2017","journal-title":"Am J Trop Med Hyg"},{"key":"bib36-20250504","doi-asserted-by":"crossref","first-page":"252","DOI":"10.3390\/toxics9100252","article-title":"Mercury chloride impacts on the development of erythrocytes and megakaryocytes in mice","volume":"9","year":"2021","journal-title":"Toxics"},{"key":"bib37-20250504","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1177\/0748233720970437","article-title":"Blood mercury and liver enzymes: a pan-India retrospective correlation study","volume":"36","year":"2020","journal-title":"Toxicol Ind Health"},{"key":"bib38-20250504","doi-asserted-by":"crossref","first-page":"e293","DOI":"10.1002\/hsr2.293","article-title":"Characteristics and treatment of elemental mercury intoxication: a case series","volume":"4","year":"2021","journal-title":"Health Sci Rep"},{"key":"bib39-20250504","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/2008-2231-22-46","article-title":"Current approaches of the management of mercury poisoning: need of the hour","volume":"22","year":"2014","journal-title":"Daru"},{"key":"bib40-20250504","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1289\/ehp.98106267","article-title":"N-acetylcysteine as an antidote in methylmercury poisoning","volume":"106","year":"1998","journal-title":"Environ Health Perspect"},{"key":"bib41-20250504","first-page":"456","article-title":"Mercury toxicity and antioxidants: part 1: role of glutathione and alpha-lipoic acid in the treatment of mercury toxicity","volume":"7","year":"2002","journal-title":"Altern Med Rev"},{"key":"bib42-20250504","doi-asserted-by":"crossref","first-page":"344","DOI":"10.3961\/jpmph.2012.45.6.344","article-title":"Human exposure and health effects of inorganic and elemental mercury","volume":"45","year":"2012","journal-title":"J Prev Med Public Health"},{"key":"bib43-20250504","doi-asserted-by":"crossref","first-page":"867","DOI":"10.14219\/jada.archive.1987.0270","article-title":"The use of mercury in dentistry: a critical review of the recent literature","volume":"115","year":"1987","journal-title":"J Am Dent Assoc"}],"container-title":["Pediatric Emergency Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/PEC.0000000000002834","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T18:09:58Z","timestamp":1746382198000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/PEC.0000000000002834"}},"subtitle":["A Single-Center Retrospective Study"],"short-title":[],"issued":{"date-parts":[[2022,9,2]]},"references-count":41,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1097\/pec.0000000000002834","relation":{},"ISSN":["1535-1815","0749-5161"],"issn-type":[{"type":"electronic","value":"1535-1815"},{"type":"print","value":"0749-5161"}],"subject":[],"published":{"date-parts":[[2022,9,2]]}}}