{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T03:53:23Z","timestamp":1784865203621,"version":"3.55.0"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Pediatr Emer Care"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n            <jats:title>Objectives<\/jats:title>\n            <jats:p>We sought to investigate the association between adherence to the American Epilepsy Society (AES) 2016 guidelines for management of convulsive status epilepticus (SE) and clinical outcomes among children requiring interhospital transport for SE. We hypothesized that pretransport guideline nonadherence would be associated with needing higher level of care posttransfer.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>This was a retrospective cohort study of children aged 30 days to 18 years transferred to our pediatric tertiary center from 2017 to 2019 for management of SE. Their care episodes were classified as 2016 American Epilepsy Society guideline adherent or nonadherent. There were 40 referring hospitals represented in this cohort.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Of 260 care episodes, 55 (21%) were guideline adherent, 184 (71%) were guideline nonadherent, and 21 (8%) had insufficient data to determine guideline adherence. Compared with the adherent group, patients in the nonadherent care group had longer hospitalizations (32 hours [17\u201368] vs 21 hours [7\u201348], <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.006), were more likely to require intensive care unit admission (47% vs 31%), and less likely to be discharged home from the emergency department (16% vs 35%; \u03c7<jats:sup>2<\/jats:sup> test, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.01). Intubation rates did not differ significantly between groups (25% vs 18%, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.37). When we fit a multivariable model to adjust for confounding variables, guideline nonadherence was associated with need for higher level of care (odds ratio, 2.04; 95% confidence interval, 1.04\u20133.99). Treatment guideline adherence did not improve over the 3-year study period (2017: 22%, 2018: 19%, 2019: 29% [\u03c7<jats:sup>2<\/jats:sup> test for differences between any 2 years, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.295]).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Guideline nonadherence pretransport was associated with longer hospitalizations and need for higher level of care among children transferred for SE at our institution. These findings suggest a need to improve SE guideline adherence through multifaceted quality improvement efforts targeting both the prehospital and community hospital settings.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/pec.0000000000002952","type":"journal-article","created":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T08:21:13Z","timestamp":1683793273000},"page":"780-785","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Treatment Guideline Nonadherence Pretransport Associated With Need for Higher Level of Care in Children Transferred to a Pediatric Tertiary Care Center for Status Epilepticus"],"prefix":"10.1097","volume":"39","author":[{"given":"Natalia Garza","family":"Philpott","sequence":"first","affiliation":[{"name":"Department of Pediatrics. Johns Hopkins University School of Medicine, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddhartha A.","family":"Dante","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Maryland School of Medicine. Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Philpott","sequence":"additional","affiliation":[{"name":"Department of Pediatrics. Johns Hopkins University School of Medicine, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie","family":"Perin","sequence":"additional","affiliation":[{"name":"Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooja","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Pediatric Transport, Johns Hopkins Children's Center, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Henderson","sequence":"additional","affiliation":[{"name":"Pediatric Transport, Johns Hopkins Children's Center, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philomena","family":"Costabile","sequence":"additional","affiliation":[{"name":"Pediatric Transport, Johns Hopkins Children's Center, Baltimore, 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