{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T04:05:05Z","timestamp":1767067505827,"version":"3.48.0"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"\n Study Objective:<\/jats:title>\n To compare the efficacy, safety, and patient experience between cyanoacrylate tissue adhesive and conventional sutures for periorbital wound closure in children.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n A prospective comparative study evaluated 145 pediatric patients with periorbital trauma treated with tissue adhesive (n=70) or conventional suturing (n=75) based on clinical assessment from September 2023 to October 2024. Primary outcomes were wound healing grades (grade I\/II\/III) and complication rates; secondary outcomes included procedure time (median, seconds), pain scores (mean, Wong-Baker FACES), Frankl behavioral compliance scores (mean), and parental satisfaction. Statistical analysis used\n t<\/jats:italic>\n tests, Mann-Whitney\n U<\/jats:italic>\n tests, and \u03c7\n 2<\/jats:sup>\n tests.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The adhesive group had significantly shorter procedure time (184 vs. 692 s,\n P<\/jats:italic>\n <0.001), lower pain scores (2.8 vs. 5.6,\n P<\/jats:italic>\n <0.001), and higher compliance (Frankl 3.1 vs. 2.3,\n P<\/jats:italic>\n <0.01). No significant differences were observed in grade I healing rates (97.1% vs. 93.3%) or complication rates (2.9% vs. 4.0%,\n P<\/jats:italic>\n =0.24).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n In pediatric periorbital trauma, use of tissue adhesive was associated with reduced treatment time and pain scores, with similar healing outcomes compared with sutures, suggesting it may serve as a viable alternative.<\/jats:p>\n <\/jats:sec>","DOI":"10.1097\/pec.0000000000003490","type":"journal-article","created":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T05:00:16Z","timestamp":1758517216000},"page":"36-41","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Tissue Adhesive as an Alternative to Sutures in Pediatric Eye Emergency"],"prefix":"10.1097","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9124-6564","authenticated-orcid":false,"given":"Jing","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuanxu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengbei","family":"Weng","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongmei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohe","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2025,9,22]]},"reference":[{"key":"R1-20251230","first-page":"CD003326","article-title":"Tissue adhesives for traumatic lacerations in children and adults","volume":"11","author":"Quinn","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"R2-20251230","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jfo.2009.01.008","article-title":"An update on the use of tissue adhesives in ophthalmology","volume":"32","author":"Vera","year":"2009","journal-title":"J Fr 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