{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T08:25:41Z","timestamp":1786955141730,"version":"build-2736575974"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Introduction:<\/jats:title>\n \n Nerium oleander<\/jats:italic>\n is well known for its toxicity due to the presence of cardiotoxic glycosides. This shrub is often involved in unintentional ingestion by children. To improve knowledge and assist health care professionals, we conducted a 12-year retrospective study in France on unintentional exposure to\n N. oleander<\/jats:italic>\n in children aged 0 to 12 years.\n <\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Data were extracted from the National Poisoning Case Database. The distribution of children according to the circumstances and the route of exposure, in addition to the type of symptoms and the clinical outcome, were specifically analysed.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n In total, 2748 cases were included. Most accidents occurred in the home. Of these, 224 (8.15%) children developed symptoms. Oral and buccal exposures were mainly associated with digestive disorders and oropharyngeal irritation, all of minor severity. The irritant effects of\n N. oleander<\/jats:italic>\n were also observed following ocular and cutaneous exposure.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n Nerium oleander<\/jats:italic>\n poisoning is relatively common in France. Our study showed that in unintentional exposures, symptoms were generally of minor severity. Nevertheless, thorough decontamination of the contact area is essential because of the plant\u2019s irritant properties.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1097\/pec.0000000000003672","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T08:00:07Z","timestamp":1786953607000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Unintentional Exposure to Nerium oleander in Children"],"prefix":"10.1097","author":[{"given":"Hadrien","family":"Legendre","sequence":"first","affiliation":[{"name":"Nouvelle Aquitaine Poison Control Centre, University Hospital Center of Bordeaux, Bordeaux"},{"name":"Forensic Medicine Department, University Hospital Center of Bordeaux, Bordeaux"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Dubois","sequence":"additional","affiliation":[{"name":"Nouvelle Aquitaine Poison Control Centre, University Hospital Center of Bordeaux, Bordeaux"},{"name":"Emergency Department, Hospital Center Robert Boulin, Libourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Brunet","sequence":"additional","affiliation":[{"name":"Nouvelle Aquitaine Poison Control Centre, University Hospital Center of Bordeaux, Bordeaux"},{"name":"Emergency Department, University Hospital Center of Bordeaux, Bordeaux"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Paradis","sequence":"additional","affiliation":[{"name":"Nouvelle Aquitaine Poison Control Centre, University Hospital Center of Bordeaux, Bordeaux"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Nardon","sequence":"additional","affiliation":[{"name":"Nouvelle Aquitaine Poison Control Centre, University Hospital Center of Bordeaux, Bordeaux"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"French PCC Research Group,","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0996-7133","authenticated-orcid":false,"given":"Arnaud","family":"Courtois","sequence":"additional","affiliation":[{"name":"Nouvelle Aquitaine Poison Control Centre, University Hospital Center of Bordeaux, Bordeaux"},{"name":"Oenology Research Unit 1366, INRAE, Institute of Vine and Wine Sciences, Villenave d\u2019Ornon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magali","family":"Labadie","sequence":"additional","affiliation":[{"name":"Nouvelle Aquitaine Poison Control Centre, University Hospital Center of Bordeaux, Bordeaux"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"R1-20260817","doi-asserted-by":"crossref","first-page":"822726","DOI":"10.3389\/fphar.2022.822726","article-title":"Oleandrin: a systematic review of its natural sources, structural properties, detection methods, pharmacokinetics and toxicology","volume":"13","author":"Zhai","year":"2022","journal-title":"Front Pharmacol"},{"key":"R2-20260817","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0300-483X(95)03296-R","article-title":"Oleander toxicity: an examination of human and animal toxic exposures","volume":"109","author":"Langford","year":"1996","journal-title":"Toxicology"},{"key":"R3-20260817","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jflm.2019.05.016","article-title":"A fatal case of self-poisoning through the ingestion of oleander leaves","volume":"65","author":"Azzalini","year":"2019","journal-title":"J Forensic Leg Med"},{"key":"R4-20260817","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3109\/15563657308990513","article-title":"Hyperkalemia in acute digitalis poisoning: prognostic significance and therapeutic implications","volume":"6","author":"Bismuth","year":"1973","journal-title":"Clin Toxicol"},{"key":"R5-20260817","doi-asserted-by":"crossref","first-page":"267","DOI":"10.5694\/j.1326-5377.1979.tb127135.x","article-title":"Oleander poisoning","volume":"2","author":"Shaw","year":"1979","journal-title":"Med J Australia"},{"key":"R6-20260817","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3109\/15563659809028940","article-title":"Poisoning severity score. 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