{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T01:59:15Z","timestamp":1787536755672,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T00:00:00Z","timestamp":1605052800000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPGN rep."],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec><jats:label\/><jats:p>Gastrointestinal bleeding is a rare but potentially life\u2010threatening manifestation of eosinophilic gastrointestinal disorders (EGIDs). Here, we describe a case series comprising 5 pediatric patients between 7 and 12 years of age, who presented to the emergency department with hematemesis and were subsequently diagnosed with EGID. Accompanying allergic history, peripheral eosinophilia, and total IgE elevation were common. Despite a more severe presentation, response to medical and dietary therapy was favorable. A comprehensive review of the literature revealed 26 other cases with similar findings that reinforced the importance of prompt recognition and early dietary and immunomodulating therapy in the control of this disease.<\/jats:p><\/jats:sec>","DOI":"10.1097\/pg9.0000000000000017","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T15:06:47Z","timestamp":1605107207000},"source":"Crossref","is-referenced-by-count":6,"title":["Upper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease"],"prefix":"10.1002","volume":"1","author":[{"given":"Elif","family":"Ozdogan","sequence":"first","affiliation":[{"name":"Department of Pediatric Gastroenterology, Hepatology and Nutrition Koc University School of Medicine Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Latife Doganay","family":"Caglayan","sequence":"additional","affiliation":[{"name":"Department of Pathology Kent Hospital Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozlem","family":"Mizikoglu","sequence":"additional","affiliation":[{"name":"Organ Transplantation Center, Liver Transplantation Koc University School of Medicine Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cigdem","family":"Arikan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology, Hepatology and Nutrition Koc University School of Medicine Istanbul Turkey"},{"name":"Organ Transplantation Center, Liver Transplantation Koc University School of Medicine Istanbul Turkey"},{"name":"Research Center for Translational Medicine (KUTTAM) Koc University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318181b1c3"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2019.10.013"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-019-0661-7"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/2391417"},{"key":"e_1_2_10_6_1","first-page":"e9549","article-title":"Carotid webs: an unusual presentation of fibromuscular dysplasia","volume":"12","author":"Priyadarshni S","year":"2020","journal-title":"Cureus"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.07.009"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2014.02.013"},{"key":"e_1_2_10_9_1","unstructured":"Soriano\u2010RamosM SalcedoLE Rodr\u00edguezGY et al. 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