{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:19:52Z","timestamp":1753877992931,"version":"3.41.2"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T00:00:00Z","timestamp":1623715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPGN rep."],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec><jats:label\/><jats:p>Anemia is encountered in up to two\u2010thirds of all patients with inflammatory bowel disease (IBD). We are reporting a case of a 9\u2010year\u2010old female with history of very early onset IBD ulcerative colitis, and primary sclerosing cholangitis who was found to have hereditary spherocytosis as the etiology of her anemia. Despite good clinical response to IBD therapy, she continued to have persistent normocytic anemia. Liver biopsy and magnetic resonance cholangiopancreatography for uptrending liver transaminases demonstrated iron deposition which led to a T2\u2010weighted magnetic resonance imaging study that quantified significant iron deposition in her liver and kidneys. Without any history of blood transfusions, these findings were concerning for hereditary hemochromatosis, but the hereditary hemochromatosis gene test was negative. Whole genome sequencing identified a pathogenic de novo variant consistent with hereditary spherocytosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Table of Contents Summary:<\/jats:title><jats:p>A novel presentation of anemia in inflammatory bowel disease<\/jats:p><\/jats:sec>","DOI":"10.1097\/pg9.0000000000000086","type":"journal-article","created":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T17:00:08Z","timestamp":1623776408000},"source":"Crossref","is-referenced-by-count":0,"title":["Hereditary Spherocytosis as an Atypical Presentation of Anemia in Ulcerative Colitis"],"prefix":"10.1002","volume":"2","author":[{"given":"Moo","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Hepatology and Nutrition University of California San Diego CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Tucker","sequence":"additional","affiliation":[{"name":"Department of Pathology University of California San Diego CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lillian","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hepatology and Nutrition University of California San Diego CA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.5223\/pghn.2019.22.2.152"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000648"},{"key":"e_1_2_5_4_1","first-page":"1525","volume-title":"Odze and Goldblum Surgical Pathology of the GI tract, Liver, Biliary Tract, and Pancreas","author":"Goldblum JR","year":"2015"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840060106"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21490"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830030212"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.17235\/reed.2016.4095\/2015"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12335"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2011.08921.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V16.1.1029.1029"}],"container-title":["JPGN Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/PG9.0000000000000086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T14:34:04Z","timestamp":1749738844000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/PG9.0000000000000086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,15]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1097\/PG9.0000000000000086"],"URL":"https:\/\/doi.org\/10.1097\/pg9.0000000000000086","archive":["Portico"],"relation":{},"ISSN":["2691-171X","2691-171X"],"issn-type":[{"type":"print","value":"2691-171X"},{"type":"electronic","value":"2691-171X"}],"subject":[],"published":{"date-parts":[[2021,6,15]]},"article-number":"e086"}}