{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T19:19:08Z","timestamp":1759778348169},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T00:00:00Z","timestamp":1706140800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/ http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n            <jats:title>Objective:<\/jats:title>\n            <jats:p>The objective of this paper is to document the feasibility of image acquisition, image optimization, and sonographic appearance of the exposed anatomic windows of cadaveric inner ear dissection for purposes of potential future clinical evaluation as part of the developing area of physical and rehabilitation space medicine.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Cadaveric dissection of the inner ear was conducted with the goal of exposing areas relevant to vestibular balance. Middle and inner ear structures of 3 human cadavers were imaged with multiple broadband transducers, including emphasis with higher frequency transducers.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>The images were best optimized with 17\u2002MHz and 22\u2002MHz small footprint transducers. High-frequency ultrasound (US) images of the semicircular canals, vestibular and facial nerves, and utricles with reflected otoliths (otoconia) were obtained and reported in this article. Detailed visualization of both the vestibular nerve and facial nerve was accomplished, including identification of fascicular architecture. In addition, US reflection from the otoliths contained within the utricle was identified with sufficient clarity to provide surface measurements. Bony acoustic landmarks of the middle ear bones were identified by scanning externally from the tympanic membrane, including the dynamic movement of the bones with manual manipulation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>US visualization has the potential to be an effective imaging modality to monitor potential changes to the otolith's size throughout extended space flight. To our knowledge, no prior study has reported US images of human inner ear structures.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/ph9.0000000000000026","type":"journal-article","created":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T21:00:09Z","timestamp":1717016409000},"page":"33-38","update-policy":"http:\/\/dx.doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Special anatomy series. Imaging inner ear structures with high-frequency ultrasound: Application to physical rehabilitation space medicine"],"prefix":"10.1097","volume":"7","author":[{"given":"Jeffrey","family":"Strakowski","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, The Ohio State University, Columbus, OH"},{"name":"Department of Physical Medicine and Rehabilitation, Ohio Health Riverside Methodist Hospital, Columbus, OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurobiology and Anatomy, McGovern University of Texas Health Science Center Houston, Houston, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Millard","family":"Reschke","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, NASA Johnson Space Center, Houston, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faye Y.","family":"Chiou-Tan","sequence":"additional","affiliation":[{"name":"H. 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