{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T02:35:50Z","timestamp":1744252550849,"version":"3.33.0"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n            <jats:title>Context<\/jats:title>\n            <jats:p>In the United States, chronic hepatitis B (CHB) virus infection predominantly affects ethnic minorities and vulnerable populations.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>We analyzed surveillance data to describe CHB epidemiology to guide hepatitis B virus (HBV) elimination efforts in Alameda County.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Design<\/jats:title>\n            <jats:p>Persons with CHB during 2017-2021 were identified by \u22652 positive HBV tests (ie, HBsAg, HbeAg, and HBV DNA) \u2265180\u00a0days apart using data from California Reportable Disease Information Exchange. Persons with CHB were stratified by age, race\/ethnicity, zip code-based Healthy Places Index (HPI), and federally designated Medically Underserved Areas (MUA). Comparisons of reported CHB prevalence between groups utilized <jats:italic toggle=\"yes\">z<\/jats:italic> test; comparisons between MUA regions utilized chi-square testing.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>A total of 8122 persons with CHB were identified; reported 5-year CHB prevalence was 0.53% (95% confidence interval: 0.52%\u20130.54%). Reported CHB 5-year prevalence was significantly higher among persons aged 50 to 69\u00a0years old than persons aged 30 to 49\u00a0years old (0.99%, 0.78%; <jats:italic toggle=\"yes\">P<\/jats:italic> &lt;\u00a0.001) and Asians, Native Hawaiian\/Pacific Islanders, African Americans compared to Whites (1.22%, 0.56%, 0.18%, 0.06%; <jats:italic toggle=\"yes\">P<\/jats:italic> &lt;\u00a0.001). Reported CHB 5-year prevalence in the 2 lowest and most disadvantaged HPI quartiles was significantly higher than the 2 highest quartiles (0.55%, 0.68%, 0.37%, 0.42%; <jats:italic toggle=\"yes\">P<\/jats:italic> &lt;\u00a0.001). The 1918 persons with CHB in MUA, compared to 5859 non-MUA persons, were significantly more likely to be African American (7%, 3%; <jats:italic toggle=\"yes\">P<\/jats:italic> &lt;\u00a0.001) and from the lowest HPI quartile (79%, 19%; <jats:italic toggle=\"yes\">P<\/jats:italic> &lt;\u00a0.001).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Reported CHB 5-year prevalence in Alameda County was 1.5 times the national prevalence estimates, and reported prevalence was highest among Asians and persons in more disadvantaged areas. Analysis of local CHB surveillance data can guide public health efforts toward HBV elimination.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/phh.0000000000002011","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T14:01:04Z","timestamp":1726149664000},"page":"116-123","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Epidemiology of Chronic Hepatitis B Virus Infection, Alameda County, California, 2017-2021"],"prefix":"10.1097","volume":"31","author":[{"given":"Emily","family":"Yette","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Marusinec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig","family":"Conlon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thi T. 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