{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T07:40:26Z","timestamp":1789630826243,"version":"build-2803163510"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Functional and aesthetic nasal operations are some of the most common plastic surgery procedures performed in the United States. The purpose of the study was to evaluate the effects of septoplasty, septorhinoplasty, and rhinoplasty procedures on postoperative olfactory function and their relationship to nasal airflow and quality of life.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>A systematic review and meta-analysis was performed evaluating olfactory function following nasal surgery. Preoperative and postoperative values for olfaction, nasal airflow, and quality of life\/nasal symptoms were analyzed. The effect size was calculated from each study and used for meta-analysis. As studies evaluated patients at different points in the postoperative period, the latest time point reported by each study was used in the meta-analysis. The 95 percent confidence interval of the effect size was calculated for each study. Study quality was assessed using the Jadad and Methodological Index for Nonrandomized Studies instruments. All included studies were Level of Evidence II.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>There were 25 included studies. Following nasal surgery, patients experienced significant improvements in olfaction (<jats:italic toggle=\"yes\">p<\/jats:italic> &lt; 0.001), nasal airflow (<jats:italic toggle=\"yes\">p<\/jats:italic> &lt; 0.001), and quality of life\/nasal symptoms (<jats:italic toggle=\"yes\">p<\/jats:italic> &lt; 0.001). Patients often experienced a transient decrease in olfaction immediately after surgery, followed by improvement postoperatively. Preoperative olfactory dysfunction rates were low and postoperative dysfunction was equally low. Olfaction improvement was directly correlated with improvement in nasal airflow and quality of life.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Functional and aesthetic nasal operations appear to significantly improve olfaction, which is directly correlated with nasal airflow. Some studies report a transient worsening of these measures in the immediate postoperative period, which subsequently improved at later time points.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/prs.0000000000007667","type":"journal-article","created":{"date-parts":[[2021,2,27]],"date-time":"2021-02-27T04:35:43Z","timestamp":1614400543000},"page":"707-718","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":23,"title":["The Effect of Functional Nasal Surgery on Olfactory Function"],"prefix":"10.1097","volume":"147","author":[{"given":"Miles J.","family":"Pfaff","sequence":"first","affiliation":[{"name":"From the Division of Plastic and Reconstructive Surgery and the David Geffen School of Medicine, University of California, Los Angeles; and New York University School of Medicine."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony A.","family":"Bertrand","sequence":"additional","affiliation":[{"name":"From the Division of Plastic and Reconstructive Surgery and the David Geffen School of Medicine, University of California, Los Angeles; and New York University School of Medicine."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelsey J.","family":"Lipman","sequence":"additional","affiliation":[{"name":"From the Division of Plastic and Reconstructive Surgery and the David Geffen School of Medicine, University of California, Los Angeles; and New York University School of Medicine."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aloukika","family":"Shah","sequence":"additional","affiliation":[{"name":"From the Division of Plastic and Reconstructive Surgery and the David Geffen School of Medicine, University of California, Los Angeles; and New York University School of Medicine."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Nolan","sequence":"additional","affiliation":[{"name":"From the Division of Plastic and Reconstructive Surgery and the David Geffen School of Medicine, University of California, Los Angeles; and New York University School of Medicine."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikram","family":"Krishna","sequence":"additional","affiliation":[{"name":"From the Division of Plastic and Reconstructive Surgery and the David Geffen School of Medicine, University of California, Los Angeles; and New York University School of Medicine."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harsh","family":"Patel","sequence":"additional","affiliation":[{"name":"From the Division of Plastic and Reconstructive Surgery and the David Geffen School of Medicine, University of California, Los Angeles; and New York University School of Medicine."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Roostaeian","sequence":"additional","affiliation":[{"name":"From the Division of Plastic and Reconstructive Surgery and the David Geffen School of Medicine, University of California, Los Angeles; and New York University School of Medicine."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine C.","family":"Lee","sequence":"additional","affiliation":[{"name":"From the Division of Plastic and Reconstructive Surgery and the David Geffen School of Medicine, University of California, Los Angeles; and New York University School of Medicine."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,2,23]]},"reference":[{"key":"R1-20250501","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/lary.20777","article-title":"Ambulatory sinus and nasal surgery in the United States: Demographics and perioperative outcomes.","volume":"120","author":"Bhattacharyya","year":"2010","journal-title":"Laryngoscope"},{"key":"R3-20250501","first-page":"195","article-title":"Assessment of olfactory function after septoplasty: A longitudinal study.","volume":"42","author":"Pfaar","year":"2004","journal-title":"Rhinology"},{"key":"R4-20250501","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1001\/archotol.128.6.635","article-title":"Characteristics of olfactory disorders in relation to major causes of olfactory loss.","volume":"128","author":"Temmel","year":"2002","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R5-20250501","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1001\/archotol.127.5.497","article-title":"Impact of olfactory impairment on quality of life and disability.","volume":"127","author":"Miwa","year":"2001","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R6-20250501","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1001\/archotol.1991.01870170065015","article-title":"Smell and taste disorders, a study of 750 patients from the University of Pennsylvania Smell and Taste Center.","volume":"117","author":"Deems","year":"1991","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R7-20250501","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1007\/s00405-019-05356-1","article-title":"Effects of septorhinoplasty on smell perception.","volume":"276","author":"Kokubo","year":"2019","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"R8-20250501","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1177\/000348940311200117","article-title":"Olfactory changes at threshold and suprathreshold levels following septoplasty with partial inferior turbinectomy.","volume":"112","author":"Damm","year":"2003","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"R9-20250501","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1093\/chemse\/27.9.831","article-title":"Intranasal volume and olfactory function.","volume":"27","author":"Damm","year":"2002","journal-title":"Chem Senses"},{"key":"R10-20250501","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/SCS.0000000000005109","article-title":"Comparison of olfactory function and quality of life with different surgical techniques for nasal septum deviation.","volume":"30","author":"Aydo\u011fdu","year":"2019","journal-title":"J Craniofac Surg"},{"key":"R11-20250501","doi-asserted-by":"crossref","first-page":"e487","DOI":"10.1097\/SCS.0000000000002805","article-title":"The effects of nasal packing and transseptal suturing after septoplasty on olfactory function, patient comfort, and mucociliary clearance.","volume":"27","author":"Dalgic","year":"2016","journal-title":"J Craniofac Surg"},{"key":"R12-20250501","first-page":"196","article-title":"Effects of septoplasty on pulmonary function tests in patients with nasal septal deviation.","volume":"39","author":"Bulcun","year":"2010","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"R13-20250501","doi-asserted-by":"crossref","first-page":"4","DOI":"10.5152\/tao.2015.694","article-title":"Effect of septorhinoplasty on olfactory function: Assessment using the Brief Smell Identification Test.","volume":"53","author":"Dengiz","year":"2015","journal-title":"Turk Arch Otorhinolaryngol"},{"key":"R14-20250501","first-page":"496542","article-title":"Will septal correction surgery for deviated nasal septum improve the sense of smell? 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