{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T21:55:19Z","timestamp":1791755719985,"version":"4.3.4"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychosom Med"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Although diagnosed arterial hypertension and antihypertensive medication usually have an adverse impact on quality of life, recent studies suggest that actual blood pressure may be positively related to better well-being. However, data in older patients with cardiovascular risk factors are lacking, for whom such an association may be of particular relevance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In 1300 adults aged 50 to 85 years with cardiovascular risk factors (51.5% men, mean age = 65.7 \u00b1 8.2 years) participating in an observational study, we performed standardized measurements of blood pressure and assessed quality of life and depressive symptoms at baseline and 1-year follow-up using the Short Form-36 (SF-36) and the Hospital Anxiety and Depression Scale (HADS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Bivariate analysis demonstrated that systolic blood pressure was associated with higher SF-36 mental component summary scores (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      = 0.100,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; .001) and reduced HADS depression (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      = \u22120.082,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = .003). Multivariate regression models adjusting for age, sex, and disease severity confirmed that higher systolic blood pressure significantly predicted both better mental quality of life (\u03b2 = 0.070,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = .012) and less depressive mood (\u03b2 = \u22120.083,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = .003) at baseline, independently of antihypertensive medication and diagnosed hypertension. Moreover, the beneficial effects of baseline systolic blood pressure remained stable for both summary components of the SF-36 as well as HADS depression at 1-year follow-up. All results remained unchanged, when limiting the analyses to the 1072 patients with diagnosed hypertension.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In older adults with cardiovascular risk factors, higher systolic blood pressure readings are independently related to better quality of life and fewer depressive symptoms in both cross-sectional and longitudinal settings, although the magnitude of the effect sizes is typically small.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/psy.0000000000000591","type":"journal-article","created":{"date-parts":[[2018,5,8]],"date-time":"2018-05-08T23:52:09Z","timestamp":1525823529000},"page":"468-474","source":"Crossref","is-referenced-by-count":28,"title":["Cross-Sectional and Longitudinal Associations of Systolic Blood Pressure With Quality of Life and Depressive Mood in Older Adults With Cardiovascular Risk Factors: Results From the Observational DIAST-CHF Study"],"prefix":"10.1097","volume":"80","author":[{"given":"Christoph","family":"Herrmann-Lingen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Bosbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mira-Lynn","family":"Chavanon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Hassoun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Edelmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Wachter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"bib1-20230824","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/HJH.0b013e328340d76f","article-title":"Health-related 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