{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:09:13Z","timestamp":1786118953793,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,9,12]]},"DOI":"10.1097\/qad.0b013e3283097d0f","type":"journal-article","created":{"date-parts":[[2008,8,27]],"date-time":"2008-08-27T03:08:33Z","timestamp":1219806513000},"page":"1885-1886","source":"Crossref","is-referenced-by-count":15,"title":["Therapeutic monitoring is necessary for the association itraconazole and efavirenz in a patient with AIDS and disseminated histoplasmosis"],"prefix":"10.1097","volume":"22","author":[{"given":"Estelle","family":"Huet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Hadji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Hulin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francoise","family":"Botterel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Bretagne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"L\u00e9vy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-27-20210130","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0378-4347(98)00451-4","article-title":"Rapid quantification of indinavir in human plasma by high-performance liquid chromatography with ultraviolet detection","volume":"721","author":"Foisy","year":"1999","journal-title":"J Chromatogr B"},{"key":"R2-27-20210130","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/00007691-199704000-00026","article-title":"A rapid and specific liquid chromatographic assay for the determination of itraconazole and hydroxyitraconazole in plasma","volume":"19","author":"Poirier","year":"1997","journal-title":"Ther Drug Monit"},{"key":"R3-27-20210130","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1136\/jcp.50.6.477","article-title":"Itraconazole solution: higher serum drug concentrations and better clinical response rates than the capsule formulation in acquired immunodeficiency syndrome patients with candidosis","volume":"50","author":"Cartledge","year":"1997","journal-title":"J Clin Pathol"},{"key":"R4-27-20210130","doi-asserted-by":"crossref","first-page":"461","DOI":"10.2165\/00003088-199835060-00004","article-title":"Optimisation of itraconazole therapy using target drug concentrations","volume":"35","author":"Poirier","year":"1998","journal-title":"Clin Pharmacokinet"},{"key":"R5-27-20210130","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1159\/000040923","article-title":"Oral and intravenous itraconazole for systemic fungal infections in neutropenic haematological patients: meeting report. London, United Kingdom, 20 June 1998","volume":"101","author":"Prentice","year":"1999","journal-title":"Acta Haematol"},{"key":"R6-27-20210130","doi-asserted-by":"crossref","first-page":"i17","DOI":"10.1093\/jac\/dki220","article-title":"Making sense of itraconazole pharmacokinetics","volume":"56","author":"Prentice","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"R7-27-20210130","first-page":"551","article-title":"Therapeutic drug monitoring of efavirenz: trough levels cannot be estimated on the basis of earlier plasma determinations","volume":"39","author":"Lopez-Cortes","year":"2005","journal-title":"J Acquir Immune Defic Syndr"},{"key":"R8-27-20210130","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/00002030-200101050-00011","article-title":"Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients","volume":"15","author":"Marzolini","year":"2001","journal-title":"AIDS"},{"key":"R9-27-20210130","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/S0002-9343(99)80311-8","article-title":"Itraconazole treatment of disseminated histoplasmosis in patients with the acquired immunodeficiency syndrome","volume":"98","author":"Wheat","year":"1995","journal-title":"Am J Med"},{"key":"R10-27-20210130","doi-asserted-by":"crossref","first-page":"e77","DOI":"10.1086\/520978","article-title":"Drug\u2013drug interaction between itraconazole and efavirenz in a patient with AIDS and disseminated histoplasmosis","volume":"45","author":"Koo","year":"2007","journal-title":"Clin Infect Dis"}],"container-title":["AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00002030-200809120-00027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:01:40Z","timestamp":1786035700000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00002030-200809120-00027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,12]]},"references-count":10,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/qad.0b013e3283097d0f","relation":{},"ISSN":["0269-9370"],"issn-type":[{"value":"0269-9370","type":"print"}],"subject":[],"published":{"date-parts":[[2008,9,12]]}}}