{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:14:18Z","timestamp":1785770058437,"version":"3.56.0"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,7,17]]},"DOI":"10.1097\/qad.0b013e328353b047","type":"journal-article","created":{"date-parts":[[2012,3,22]],"date-time":"2012-03-22T15:48:16Z","timestamp":1332431296000},"page":"1399-1401","source":"Crossref","is-referenced-by-count":64,"title":["Discontinuation of Atripla as first-line therapy in HIV-1 infected individuals"],"prefix":"10.1097","volume":"26","author":[{"given":"Andrew","family":"Scourfield","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiexin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suchitra","family":"Chinthapalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Waters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sundhiya","family":"Mandalia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-10-20210130","first-page":"103","article-title":"Neuropsychiatric symptoms associated with efavirenz: prevalence, correlates, and management. A neurobehavioral review.","volume":"11","author":"Munoz-Moreno","year":"2009","journal-title":"AIDS Rev"},{"key":"R3-10-20210130","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/QAD.0b013e328341685b","article-title":"A phase IV, double-blind, multicentre, randomized, placebo-controlled, pilot study to assess the feasibility of switching individuals receiving efavirenz with continuing central nervous system adverse events to etravirine.","volume":"25","author":"Waters","year":"2011","journal-title":"AIDS"},{"key":"R4-10-20210130","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/QAD.0b013e32833f9f63","article-title":"A randomized crossover study to compare efavirenz and etravirine treatment.","volume":"25","author":"Nguyen","year":"2011","journal-title":"AIDS"},{"key":"R5-10-20210130","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s00228-011-1118-0","article-title":"CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans.","volume":"68","author":"Maimbo","year":"2012","journal-title":"Eur J Clin Pharmacol"},{"key":"R6-10-20210130","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1093\/jac\/dkr272","article-title":"Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens.","volume":"66","author":"Wyen","year":"2011","journal-title":"J Antimicrob Chemother"}],"container-title":["AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00006842-200307000-00034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T14:25:43Z","timestamp":1785767143000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00002030-201207170-00010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,17]]},"references-count":5,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/qad.0b013e328353b047","relation":{},"ISSN":["0269-9370"],"issn-type":[{"value":"0269-9370","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7,17]]}}}