{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:49:02Z","timestamp":1789674542550,"version":"4.0.1"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,9,1]]},"DOI":"10.1097\/qai.0b013e31817bec64","type":"journal-article","created":{"date-parts":[[2008,8,22]],"date-time":"2008-08-22T03:07:27Z","timestamp":1219374447000},"page":"26-31","source":"Crossref","is-referenced-by-count":72,"title":["Influence of HAART on the Clinical Course of HIV-1-Infected Patients With Progressive Multifocal Leukoencephalopathy: Results of an Observational Multicenter Study"],"prefix":"10.1097","volume":"49","author":[{"given":"Vicen\u00e7","family":"Falc\u00f3","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Olmo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara Villar","family":"del Saz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Guelar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 R","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar","family":"Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Colomer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabet","family":"Deig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gracia","family":"Mateo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milagro","family":"Montero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enric","family":"Pedrol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Podzamczer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pere","family":"Domingo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep M","family":"Llibre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R3-4-20210131","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1212\/01.wnl.0000242728.26433.12","article-title":"Immune reconstitution inflammatory syndrome associated with PML in AIDS: a treatable disorder.","volume":"67","author":"Martinez","year":"2006","journal-title":"Neurology"},{"issue":"Suppl 3","key":"R4-4-20210131","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1080\/13550280500511741","article-title":"Central nervous system immune reconstitution disease in acquired immunodeficiency syndrome patients receiving highly active antiretroviral treatment.","volume":"11","author":"Gray","year":"2005","journal-title":"J Neurovirol"},{"key":"R5-4-20210131","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1097\/01.aids.0000196175.88421.eb","article-title":"Inflammatory progressive multifocal leukoencephalopathy after antiretroviral treatment.","volume":"20","author":"Silva","year":"2006","journal-title":"AIDS"},{"key":"R6-4-20210131","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.1212\/01.WNL.0000148585.41802.6C","article-title":"Fatal inflammatory AIDS-associated PML with high CD4 counts on HAART: a new clinical entity?","volume":"63","author":"Di Giambenedetto","year":"2004","journal-title":"Neurology"},{"key":"R7-4-20210131","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s00401-005-0983-y","article-title":"Fulminant inflammatory leukoencephalopathy associated with HAART-induced immune restoration in AIDS-related progressive multifocal leukoencephalopathy.","volume":"109","author":"Vendrely","year":"2005","journal-title":"Acta Neuropathol (Berl)"},{"key":"R8-4-20210131","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1086\/344056","article-title":"Fatal immune restoration disease in human immunodeficiency virus type1-infected patients with progressive multifocal leukoencephalopathy: impact of antiretroviral therapy-associated immune reconstitution.","volume":"35","author":"Safdar","year":"2002","journal-title":"Clin Infect Dis"},{"key":"R9-4-20210131","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/jac\/dki444","article-title":"Immune reconstitution inflammatory syndrome: more answers, more questions.","volume":"57","author":"Shelburne","year":"2006","journal-title":"J Antimicrob Chemother"},{"key":"R10-4-20210131","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1086\/374048","article-title":"Clinical course and prognostic factors of progressive multifocal leukoencephalopathy in patients treated with highly active antiretroviral therapy.","volume":"36","author":"Berenguer","year":"2003","journal-title":"Clin Infect Dis"},{"key":"R11-4-20210131","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1002\/ana.20933","article-title":"Progressive multifocal leukoencephalopathy revisited: has the disease outgrown its name?","volume":"60","author":"Koralnik","year":"2006","journal-title":"Ann Neurol"},{"issue":"Suppl 1","key":"R12-4-20210131","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1080\/13550280390195388","article-title":"Clinical epidemiology and survival of progressive multifocal leukoencephalopathy in the era of highly active antiretroviral therapy: data from the Italian Registry Investigative Neuro AIDS (IRINA).","volume":"9","author":"Antinori","year":"2003","journal-title":"J Neurovirol"},{"issue":"Suppl 1","key":"R13-4-20210131","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/13550280390195351","article-title":"The effect of highly active antiretroviral therapy-induced immune reconstitution on development and outcome of progressive multifocal leukoencephalopathy: study of 43 cases with review of the literature.","volume":"9","author":"Cinque","year":"2003","journal-title":"J Neurovirol"},{"key":"R14-4-20210131","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1097\/01.qai.0000136093.47316.f3","article-title":"Progressive multifocal leukencephalopathy in patients on highly active antiretroviral therapy: survival and risk factors of death.","volume":"37","author":"Wyen","year":"2004","journal-title":"J Acquir Immune Defic Syndr"},{"key":"R15-4-20210131","first-page":"1720","article-title":"Progressive multifocal leukoencephalopathy following initiation of highly active antiretroviral therapy.","volume":"12","author":"Mayo","year":"1998","journal-title":"AIDS"},{"key":"R16-4-20210131","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1097\/00002030-200109280-00028","article-title":"Inflammatory reactions in progressive multifocal leukoencephalopathy after highly active antiretroviral therapy.","volume":"15","author":"Miralles","year":"2001","journal-title":"AIDS"},{"issue":"Suppl 1","key":"R17-4-20210131","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1080\/13550280390195315","article-title":"Inflammatory reaction in progressive multifocal leukoencephalopathy: harmful or beneficial?","volume":"9","author":"Du Pasquier","year":"2003","journal-title":"J Neurovirol"},{"key":"R18-4-20210131","doi-asserted-by":"crossref","first-page":"4175","DOI":"10.1128\/JCM.43.8.4175-4177.2005","article-title":"Reduced rate of diagnostic positive detection of JC virus DNA in cerebrospinal fluid in cases of suspected progressive multifocal leukoencephalopathy in the era of potent antiretroviral therapy.","volume":"43","author":"Marzocchetti","year":"2005","journal-title":"J Clin Microbiol"},{"issue":"Suppl 1","key":"R19-4-20210131","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1080\/13550280390195298","article-title":"The evolving face of human immunodeficiency virus-related progressive multifocal leukoencephalopathy: defining a consensus terminology.","volume":"9","author":"Cinque","year":"2003","journal-title":"J Neurovirol"},{"key":"R21-4-20210131","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1097\/00002030-200209060-00012","article-title":"A pilot study of cidofovir for progressive multifocal leukoencephalopathy in AIDS.","volume":"16","author":"Marra","year":"2002","journal-title":"AIDS"},{"key":"R22-4-20210131","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1056\/NEJM199805073381903","article-title":"Failure of cytarabine in progressive multifocal leukoencephalopathy associated with human immunodeficiency virus.","volume":"19","author":"Hall","year":"1998","journal-title":"N Engl J Med"},{"key":"R23-4-20210131","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1086\/314937","article-title":"Progressive multifocal leukoencephalopathy: improved survival of human immunodeficiency virus-infected patients in the protease inhibitor era.","volume":"180","author":"Dworkin","year":"1999","journal-title":"J Infect Dis"}],"container-title":["JAIDS Journal of Acquired Immune Deficiency Syndromes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00126334-200809010-00004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:14:25Z","timestamp":1786036465000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00126334-200809010-00004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/qai.0b013e31817bec64","relation":{},"ISSN":["1525-4135"],"issn-type":[{"value":"1525-4135","type":"print"}],"subject":[],"published":{"date-parts":[[2008,9,1]]}}}