{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T12:55:50Z","timestamp":1793710550566,"version":"4.6.1"},"reference-count":44,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,8,15]]},"DOI":"10.1097\/qai.0b013e3182237e54","type":"journal-article","created":{"date-parts":[[2011,6,4]],"date-time":"2011-06-04T08:23:07Z","timestamp":1307175787000},"page":"371-379","source":"Crossref","is-referenced-by-count":197,"title":["Plasma sCD14 Is a Biomarker Associated With Impaired Neurocognitive Test Performance in Attention and Learning Domains in HIV Infection"],"prefix":"10.1097","volume":"57","author":[{"given":"Jennifer L","family":"Lyons","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Uno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petronela","family":"Ancuta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anupa","family":"Kamat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elyse J","family":"Singer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Morgello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Gabuzda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20210131","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1002\/ana.22053","article-title":"Human immunodeficiency virus-associated neurocognitive disorders: mind the gap.","volume":"67","author":"McArthur","year":"2010","journal-title":"Ann Neurol"},{"key":"R2-4-20210131","first-page":"94","article-title":"HIV-associated neurocognitive disease continues in the antiretroviral era.","volume":"16","author":"Clifford","year":"2008","journal-title":"Top HIV Med"},{"key":"R3-4-20210131","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/ana.21225","article-title":"Changes in the incidence and predictors of human immunodeficiency virus-associated dementia in the era of highly active antiretroviral therapy.","volume":"63","author":"Bhaskaran","year":"2008","journal-title":"Ann Neurol"},{"key":"R4-4-20210131","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1750-3639.2003.tb00019.x","article-title":"Changing patterns in the neuropathogenesis of HIV during the HAART era.","volume":"13","author":"Langford","year":"2003","journal-title":"Brain Pathol"},{"key":"R5-4-20210131","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/13550280290101094","article-title":"The epidemiology of human immunodeficiency virus-associated neurological disease in the era of highly active antiretroviral therapy.","volume":"8","author":"Sacktor","year":"2002","journal-title":"J Neurovirol"},{"key":"R6-4-20210131","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1001\/archneur.61.11.1687","article-title":"Attenuated central nervous system infection in advanced HIV\/AIDS with combination antiretroviral therapy.","volume":"61","author":"McArthur","year":"2004","journal-title":"Arch Neurol"},{"key":"R7-4-20210131","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1212\/WNL.56.2.257","article-title":"HIV-associated neurologic disease incidence changes: Multicenter AIDS Cohort Study, 1990-1998.","volume":"56","author":"Sacktor","year":"2001","journal-title":"Neurology"},{"key":"R8-4-20210131","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/nri1527","article-title":"The neuropathogenesis of AIDS.","volume":"5","author":"Gonzalez-Scarano","year":"2005","journal-title":"Nat Rev Immunol"},{"key":"R9-4-20210131","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1001\/archneur.64.1.97","article-title":"An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection.","volume":"64","author":"Sevigny","year":"2007","journal-title":"Arch Neurol"},{"key":"R10-4-20210131","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/09540260701878082","article-title":"Biomarkers of HIV related central nervous system disease.","volume":"20","author":"Brew","year":"2008","journal-title":"Int Rev Psychiatry"},{"key":"R11-4-20210131","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1212\/01.wnl.0000260610.79853.47","article-title":"Associative and predictive biomarkers of dementia in HIV-1-infected patients.","volume":"68","author":"Bandaru","year":"2007","journal-title":"Neurology"},{"key":"R12-4-20210131","doi-asserted-by":"crossref","first-page":"e2516","DOI":"10.1371\/journal.pone.0002516","article-title":"Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients.","volume":"3","author":"Ancuta","year":"2008","journal-title":"PLoS One"},{"key":"R13-4-20210131","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1182\/blood.V92.6.2084.418k26_2084_2092","article-title":"Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events.","volume":"92","author":"Lien","year":"1998","journal-title":"Blood"},{"key":"R14-4-20210131","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1086\/323036","article-title":"Plasma levels of soluble CD14 and tumor necrosis factor-alpha type II receptor correlate with cognitive dysfunction during human immunodeficiency virus type 1 infection.","volume":"184","author":"Ryan","year":"2001","journal-title":"J Infect Dis"},{"key":"R15-4-20210131","doi-asserted-by":"crossref","first-page":"3117","DOI":"10.1073\/pnas.95.6.3117","article-title":"Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia.","volume":"95","author":"Conant","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R16-4-20210131","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1038\/nm1511","article-title":"Microbial translocation is a cause of systemic immune activation in chronic HIV infection.","volume":"12","author":"Brenchley","year":"2006","journal-title":"Nat Med"},{"key":"R17-4-20210131","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1002\/ana.410190602","article-title":"The AIDS dementia complex: I. Clinical features.","volume":"19","author":"Navia","year":"1986","journal-title":"Ann Neurol"},{"key":"R18-4-20210131","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/09540260701877894","article-title":"Neurocognitive disturbances in HIV.","volume":"20","author":"Grant","year":"2008","journal-title":"Int Rev Psychiatry"},{"key":"R19-4-20210131","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1212\/01.WNL.0000287431.88658.8b","article-title":"Updated research nosology for HIV-associated neurocognitive disorders.","volume":"69","author":"Antinori","year":"2007","journal-title":"Neurology"},{"key":"R20-4-20210131","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1176\/ajp.153.9.1195","article-title":"Psychiatric Research Interview for Substance and Mental Disorders (PRISM): reliability for substance abusers.","volume":"153","author":"Hasin","year":"1996","journal-title":"Am J Psychiatry"},{"key":"R21-4-20210131","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1001\/archpsyc.1988.01800360017003","article-title":"The Composite International Diagnostic Interview. An epidemiologic instrument suitable for use in conjunction with different diagnostic systems and in different cultures.","volume":"45","author":"Robins","year":"1988","journal-title":"Arch Gen Psychiatry"},{"key":"R22-4-20210131","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1080\/13803390490509565","article-title":"Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV.","volume":"26","author":"Woods","year":"2004","journal-title":"J Clin Exp Neuropsychol"},{"key":"R23-4-20210131","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1007\/s11481-006-9018-2","article-title":"Neurobiology of multiple insults: HIV-1-associated brain disorders in those who use illicit drugs.","volume":"1","author":"Bell","year":"2006","journal-title":"J Neuroimmune Pharmacol"},{"key":"R24-4-20210131","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s11065-009-9101-6","article-title":"Drug abuse and hepatitis C infection as comorbid features of HIV associated neurocognitive disorder: neurocognitive and neuroimaging features.","volume":"19","author":"Martin-Thormeyer","year":"2009","journal-title":"Neuropsychol Rev"},{"key":"R25-4-20210131","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1086\/519285","article-title":"Pathogenesis of hepatitis C virus coinfection in the brains of patients infected with HIV.","volume":"196","author":"Letendre","year":"2007","journal-title":"J Infect Dis"},{"key":"R26-4-20210131","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1055\/s-2005-864787","article-title":"The nervous system and hepatitis C virus.","volume":"25","author":"Morgello","year":"2005","journal-title":"Semin Liver Dis"},{"key":"R27-4-20210131","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1097\/01.aids.0000238404.16121.47","article-title":"Neurocognitive functioning and HAART in HIV and hepatitis C virus co-infection.","volume":"20","author":"Parsons","year":"2006","journal-title":"AIDS"},{"key":"R28-4-20210131","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1080\/09540260701862037","article-title":"The neuropathology of HIV\/AIDS.","volume":"20","author":"Anthony","year":"2008","journal-title":"Int Rev Psychiatry"},{"key":"R29-4-20210131","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1097\/QAD.0b013e3283427da7","article-title":"Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment.","volume":"25","author":"Harezlak","year":"2011","journal-title":"AIDS"},{"key":"R30-4-20210131","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/jnen\/64.6.529","article-title":"Influence of HAART on HIV-related CNS disease and neuroinflammation.","volume":"64","author":"Anthony","year":"2005","journal-title":"J Neuropathol Exp Neurol"},{"key":"R31-4-20210131","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1742-4690-7-30","article-title":"Molecular mechanisms of neuroinvasion by monocytes-macrophages in HIV-1 infection.","volume":"7","author":"Gras","year":"2010","journal-title":"Retrovirology"},{"key":"R32-4-20210131","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1189\/jlb.0405222","article-title":"Are chemokines the third major system in the brain?","volume":"78","author":"Adler","year":"2005","journal-title":"J Leukoc Biol"},{"key":"R33-4-20210131","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1111\/j.1365-2559.2004.02004.x","article-title":"An update on the neuropathology of HIV in the HAART era.","volume":"45","author":"Bell","year":"2004","journal-title":"Histopathology"},{"key":"R34-4-20210131","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1080\/13550280390194109","article-title":"Human immunodeficiency virus-associated dementia: an evolving disease.","volume":"9","author":"McArthur","year":"2003","journal-title":"J Neurovirol"},{"key":"R35-4-20210131","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1126\/science.287.5453.602","article-title":"HIV infection and dementia.","volume":"287","author":"Gartner","year":"2000","journal-title":"Science"},{"key":"R36-4-20210131","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3109\/13550280903559789","article-title":"Peripheral biomarkers do not correlate with cognitive impairment in highly active antiretroviral therapy-treated subjects with human immunodeficiency virus type 1 infection.","volume":"16","author":"Sun","year":"2010","journal-title":"J Neurovirol"},{"key":"R37-4-20210131","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1089\/aid.2007.0310","article-title":"Nadir CD4 cell count predicts neurocognitive impairment in HIV-infected patients.","volume":"24","author":"Munoz-Moreno","year":"2008","journal-title":"AIDS Res Hum Retroviruses"},{"key":"R38-4-20210131","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1080\/13550280600915339","article-title":"Lowest ever CD4 lymphocyte count (CD4 nadir) as a predictor of current cognitive and neurological status in human immunodeficiency virus type 1 infectionThe Hawaii Aging with HIV Cohort.","volume":"12","author":"Valcour","year":"2006","journal-title":"J Neurovirol"},{"key":"R39-4-20210131","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1192\/bjp.161.4.522","article-title":"The Edinburgh cohort of HIV-positive drug users: pattern of cognitive impairment in relation to progression of disease.","volume":"161","author":"Egan","year":"1992","journal-title":"Br J Psychiatry"},{"key":"R40-4-20210131","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1212\/WNL.42.10.1924","article-title":"HIV-1 infection and intravenous drug use: longitudinal neuropsychological evaluation of asymptomatic subjects.","volume":"42","author":"Selnes","year":"1992","journal-title":"Neurology"},{"key":"R41-4-20210131","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1212\/WNL.41.12.1905","article-title":"HIV-1 infection and nervous system abnormalities among a cohort of intravenous drug users.","volume":"41","author":"Royal","year":"1991","journal-title":"Neurology"},{"key":"R42-4-20210131","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1212\/01.WNL.0000115177.74976.6C","article-title":"Neuropsychiatric impact of hepatitis C on advanced HIV.","volume":"62","author":"Ryan","year":"2004","journal-title":"Neurology"},{"key":"R43-4-20210131","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1300\/J069v27n02_02","article-title":"Neurocognition in individuals co-infected with HIV and hepatitis C.","volume":"27","author":"Hinkin","year":"2008","journal-title":"J Addict Dis"},{"key":"R44-4-20210131","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1212\/WNL.0b013e3181af7a10","article-title":"Effects of active HCV replication on neurologic status in HIV RNA virally suppressed patients.","volume":"73","author":"Clifford","year":"2009","journal-title":"Neurology"}],"container-title":["JAIDS Journal of Acquired Immune Deficiency Syndromes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/QAI.0b013e3182237e54","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,7]],"date-time":"2024-04-07T09:30:45Z","timestamp":1712482245000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00126334-201108150-00004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8,15]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/qai.0b013e3182237e54","relation":{},"ISSN":["1525-4135"],"issn-type":[{"value":"1525-4135","type":"print"}],"subject":[],"published":{"date-parts":[[2011,8,15]]}}}