{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:07:33Z","timestamp":1790082453055,"version":"4.0.1"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Comput Assist Tomogr"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>The aim of this study was to determine the prevalence and computed tomography (CT) features of malignancy in incidental focal fundal gallbladder wall thickening.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Patients with incidental focal fundal gallbladder wall thickening on CT were included if they had an ultrasound or magnetic resonance imaging diagnostic of the etiology (n = 19), stability on CT for 1 year (n = 84), or pathological correlation (n = 13). Morphologies were classified as type 1 (nodular\/pinched intramural low attenuation), type 2 (intramural low attenuation), type 3 (homogeneous enhancement), type 4 (nodular\/pinched homogeneous enhancement), type 5 (intramural cystic spaces), or type 6 (hyperenhancing\/heterogeneous enhancement).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>One hundred sixteen patients had the following morphologies: type 1 (n = 57), type 2 (n = 10), type 3 (n = 6), type 4 (n = 19), type 5 (n = 14), and type 6 (n = 10). Four cases (3.4%; 95% confidence interval, 0.9%\u20138.6%) of malignancy were identified (type 6 in 3 and type 3 in 1).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Incidental focal fundal gallbladder wall thickening is usually benign. Computed tomography features help distinguish benign from malignant etiologies.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/rct.0000000000000802","type":"journal-article","created":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T03:10:06Z","timestamp":1540782606000},"page":"149-154","source":"Crossref","is-referenced-by-count":17,"title":["Incidentally Detected Focal Fundal Gallbladder Wall Thickening at Contrast-Enhanced Computed Tomography: Prevalence and Computed Tomography Features of Malignancy"],"prefix":"10.1097","volume":"43","author":[{"given":"Michael T.","family":"Corwin","sequence":"first","affiliation":[{"name":"Department of Radiology, University of California, Davis Medical Center, Sacramento; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satinderpal S.","family":"Khera","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of California, Davis Medical Center, Sacramento; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas W.","family":"Loehfelm","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of California, Davis Medical Center, Sacramento; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuen Tsang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, University of California, Davis, Davis, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghaneh","family":"Fananapazir","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of California, Davis Medical Center, Sacramento; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"bib1-20230927","doi-asserted-by":"crossref","first-page":"W1","DOI":"10.2214\/AJR.12.10386","article-title":"Gallbladder wall thickening","volume":"202","year":"2014","journal-title":"AJR Am J Roentgenol"},{"key":"bib2-20230927","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1148\/rg.263055180","article-title":"Best cases from the AFIP: adenomyomatosis of the gallbladder","volume":"26","year":"2006","journal-title":"Radiographics"},{"key":"bib3-20230927","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.hpb.2015.09.006","article-title":"A literature review of radiological findings to guide the diagnosis of gallbladder adenomyomatosis","volume":"18","year":"2016","journal-title":"HPB (Oxford)"},{"key":"bib4-20230927","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1245\/s10434-009-0538-x","article-title":"Evolving treatment strategies for gallbladder cancer","volume":"16","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"bib5-20230927","first-page":"967472","article-title":"Gallbladder cancer in the 21st century","volume":"2015","year":"2015","journal-title":"J Oncol"},{"key":"bib6-20230927","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1148\/radiographics.21.2.g01mr16295","article-title":"Gallbladder carcinoma: radiologic-pathologic correlation","volume":"21","year":"2001","journal-title":"Radiographics"},{"key":"bib7-20230927","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.jacr.2013.05.022","article-title":"Managing incidental findings on abdominal and pelvic CT and MRI, part 4: white paper of the ACR Incidental Findings Committee II on gallbladder and biliary findings","volume":"10","year":"2013","journal-title":"J Am Coll Radiol"},{"key":"bib8-20230927","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s00261-005-0230-y","article-title":"Gallbladder adenomyomatosis: imaging findings","volume":"31","year":"2006","journal-title":"Abdom Imaging"},{"key":"bib9-20230927","doi-asserted-by":"crossref","first-page":"62","DOI":"10.2214\/AJR.06.0866","article-title":"CT differentiation of adenomyomatosis and gallbladder cancer","volume":"189","year":"2007","journal-title":"AJR Am J Roentgenol"},{"key":"bib10-20230927","doi-asserted-by":"crossref","first-page":"765","DOI":"10.2214\/AJR.07.3331","article-title":"Analysis of enhancement pattern of flat gallbladder wall thickening on MDCT to differentiate gallbladder cancer from cholecystitis","volume":"191","year":"2008","journal-title":"AJR Am J Roentgenol"},{"key":"bib11-20230927","first-page":"102","article-title":"Gallbladder carcinoma and chronic cholecystitis: differentiation with two-phase spiral CT","volume":"29","year":"2004","journal-title":"Abdom Imaging"},{"key":"bib12-20230927","doi-asserted-by":"crossref","first-page":"219","DOI":"10.5009\/gnl.2014.8.2.219","article-title":"Focal thickening at the fundus of the gallbladder: computed tomography differentiation of fundal type adenomyomatosis and localized chronic cholecystitis","volume":"8","year":"2014","journal-title":"Gut Liver"}],"container-title":["Journal of Computer Assisted Tomography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00004728-201901000-00022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T18:10:58Z","timestamp":1695838258000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00004728-201901000-00022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1097\/rct.0000000000000802","relation":{},"ISSN":["1532-3145","0363-8715"],"issn-type":[{"value":"1532-3145","type":"electronic"},{"value":"0363-8715","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]}}}