{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T15:06:02Z","timestamp":1789311962074,"version":"build-2803163510"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T00:00:00Z","timestamp":1636588800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["J Comput Assist Tomogr"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>This study aimed to investigate the value of contrast-enhanced 3-dimensional (3D) T2-weighted (T2W) Volume Isotropic Turbo Spin Echo Acquisition (VISTA) sequence in prolactin-secreting pituitary adenoma diagnosis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>We enrolled 158 patients with hyperprolactinemia. Coronal dynamic contrast-enhanced (DCE) T1 spin echo and T2W VISTA sequences were performed. The detection of pituitary microadenomas in 3 imaging groups (DCE magnetic resonance imaging [MRI], VISTA, and DCE MRI + VISTA) were compared using McNemar test and \u03c7<jats:sup>2<\/jats:sup> test.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The DCE MRI + VISTA group detected 28 more pituitary microlesions than DCE MRI alone. Among these, 20 lesions were clearly observed on VISTA images but were negative on DCE MRI. The combined sequences showed higher sensitivity (85.3%) and diagnostic accuracy (89.2%) for adenoma detection than any of the sequences alone (<jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.01). We noted that in 65.7% of the patients with adenoma (46 of 70), a \u201chypointense rim\u201d was present around the lesion on the VISTA images. Of them, 11 patients underwent surgery. Histopathology confirmed that the \u201chypointense rim\u201d was a pseudocapsular structure at the edge of the adenoma.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>For patients with hyperprolactinemia, the 3D T2W VISTA sequence is an important supplement to DCE MRI, because it could improve the detection rate of pituitary microadenomas.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/rct.0000000000001237","type":"journal-article","created":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T04:01:08Z","timestamp":1636603268000},"page":"116-123","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Application of Contrast-Enhanced 3-Dimensional T2-Weighted Volume Isotropic Turbo Spin Echo Acquisition Sequence in the Diagnosis of Prolactin-Secreting Pituitary Microadenomas"],"prefix":"10.1097","volume":"46","author":[{"given":"Rui","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Radiology, Liuzhou People Hospital, Liuzhou"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangcheng","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Radiology, Liuzhou People Hospital, Liuzhou"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyang","family":"Zhou","sequence":"additional","affiliation":[{"name":"Endocrinology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoutang","family":"Liu","sequence":"additional","affiliation":[{"name":"Neurosurgery, Liuzhou People Hospital, Liuzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenwei","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Radiology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunping","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Radiology, Liuzhou People Hospital, Liuzhou"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,11,11]]},"reference":[{"key":"bib1-20250802","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s00401-016-1545-1","article-title":"The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary","volume":"131","year":"2016","journal-title":"Acta Neuropathol"},{"key":"bib2-20250802","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1109\/JBHI.2017.2715078","article-title":"Optimized 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