{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T11:52:59Z","timestamp":1774353179932,"version":"3.50.1"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Nucl Med"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>This American College of Radiology and American College of Nuclear Medicine joint clinical practice parameter is for performance of dopamine transporter single photon emission computed tomography (SPECT) imaging, for patients with movement disorders. Parkinsonian syndrome (PS) consists of a group of neurodegenerative diseases including Parkinson disease (PD), progressive supranuclear palsy (PSP), multiple system atrophy (MSA), corticobasal degeneration (CBD), and dementia with Lewy bodies (DLB). Accurate diagnosis of PS is critical for clinical management. An important diagnostic dilemma is the differentiation of PS and non-neurodegenerative disorders, such as essential tremor (ET) or drug-induced tremor, due to the overlap of clinical symptoms. The management approach to these conditions is distinctly different. An abnormal iodine-123 ioflupane SPECT scan suggests a decreased amount of dopamine transporter in the striatum, that is, a diagnosis of nigrostriatal neurodegenerative PS, whereas a normal scan suggests ET or other nondegenerative parkinsonism (drug-induced, vascular, or psychogenic).<\/jats:p>","DOI":"10.1097\/rlu.0000000000001815","type":"journal-article","created":{"date-parts":[[2017,9,15]],"date-time":"2017-09-15T20:18:02Z","timestamp":1505506682000},"page":"847-852","source":"Crossref","is-referenced-by-count":16,"title":["ACR\u2013ACNM Practice Parameter for the Performance of Dopamine Transporter (DaT) Single Photon Emission Computed Tomography (SPECT) Imaging for Movement Disorders"],"prefix":"10.1097","volume":"42","author":[{"given":"Rathan M.","family":"Subramaniam","sequence":"first","affiliation":[{"name":"From the *UT Southwestern; \u2020University of Michigan; \u2021Mayo Clinic; \u00a7Boston Medical Center; \u2225Johns Hopkins University; \u00b6LAC-USC Medical Center; **MD Anderson Cancer Center, Houston, TX; \u2020\u2020Loyola University Medical Center; and \u2021\u2021Medical College of Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirk A.","family":"Frey","sequence":"additional","affiliation":[{"name":"From the *UT Southwestern; \u2020University of Michigan; \u2021Mayo Clinic; \u00a7Boston Medical Center; \u2225Johns Hopkins University; \u00b6LAC-USC Medical Center; **MD Anderson Cancer Center, Houston, TX; \u2020\u2020Loyola University Medical Center; and \u2021\u2021Medical College of Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher H.","family":"Hunt","sequence":"additional","affiliation":[{"name":"From the *UT Southwestern; \u2020University of Michigan; \u2021Mayo Clinic; \u00a7Boston Medical Center; \u2225Johns Hopkins University; \u00b6LAC-USC Medical Center; **MD Anderson Cancer Center, Houston, TX; \u2020\u2020Loyola University Medical Center; and \u2021\u2021Medical College of Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo A.","family":"Mercier","sequence":"additional","affiliation":[{"name":"From the *UT Southwestern; \u2020University of Michigan; \u2021Mayo Clinic; \u00a7Boston Medical Center; \u2225Johns Hopkins University; \u00b6LAC-USC Medical Center; **MD Anderson Cancer Center, Houston, TX; \u2020\u2020Loyola University Medical Center; and \u2021\u2021Medical College of Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilja B.","family":"Solnes","sequence":"additional","affiliation":[{"name":"From the *UT Southwestern; \u2020University of Michigan; \u2021Mayo Clinic; \u00a7Boston Medical Center; \u2225Johns Hopkins University; \u00b6LAC-USC Medical Center; **MD Anderson Cancer Center, Houston, TX; \u2020\u2020Loyola University Medical Center; and \u2021\u2021Medical College of Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick M.","family":"Colletti","sequence":"additional","affiliation":[{"name":"From the *UT Southwestern; \u2020University of Michigan; \u2021Mayo Clinic; \u00a7Boston Medical Center; \u2225Johns Hopkins University; \u00b6LAC-USC Medical Center; **MD Anderson Cancer Center, Houston, TX; \u2020\u2020Loyola University Medical Center; and \u2021\u2021Medical College of Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Lu","sequence":"additional","affiliation":[{"name":"From the *UT Southwestern; \u2020University of Michigan; \u2021Mayo Clinic; \u00a7Boston Medical Center; \u2225Johns Hopkins University; \u00b6LAC-USC Medical Center; **MD Anderson Cancer Center, Houston, TX; \u2020\u2020Loyola University Medical Center; and \u2021\u2021Medical College of Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bital","family":"Savir-Baruch","sequence":"additional","affiliation":[{"name":"From the *UT Southwestern; \u2020University of Michigan; \u2021Mayo Clinic; \u00a7Boston Medical Center; \u2225Johns Hopkins University; \u00b6LAC-USC Medical Center; **MD Anderson Cancer Center, Houston, TX; \u2020\u2020Loyola University Medical Center; and \u2021\u2021Medical College of Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadyn T.","family":"Williams","sequence":"additional","affiliation":[{"name":"From the *UT Southwestern; \u2020University of Michigan; \u2021Mayo Clinic; \u00a7Boston Medical Center; \u2225Johns Hopkins University; \u00b6LAC-USC Medical Center; **MD Anderson Cancer Center, Houston, TX; \u2020\u2020Loyola University Medical Center; and \u2021\u2021Medical College of Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"bib2-20230925","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S1474-4422(06)70471-9","article-title":"Epidemiology of Parkinson's disease","volume":"5","year":"2006","journal-title":"The Lancet Neurology"},{"key":"bib3-20230925","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1056\/NEJM2003ra020003","article-title":"Alzheimer's disease and Parkinson's disease","volume":"348","year":"2003","journal-title":"N Engl J Med"},{"key":"bib4-20230925","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/mds.10305","article-title":"Systematic review of incidence studies of Parkinson's disease","volume":"18","year":"2003","journal-title":"Mov Disord"},{"key":"bib5-20230925","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1056\/NEJM199601113340202","article-title":"Prevalence of parkinsonian signs and associated mortality in a community population of older people","volume":"334","year":"1996","journal-title":"N Engl J Med"},{"issue":"Pt 4","key":"bib6-20230925","first-page":"861","article-title":"The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service","volume":"125","year":"2002","journal-title":"Brain: a journal of neurology"},{"key":"bib7-20230925","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1001\/archneur.60.3.405","article-title":"Rest tremor in patients with essential tremor: prevalence, clinical correlates, and electrophysiologic characteristics","volume":"60","year":"2003","journal-title":"Arch Neurol"},{"key":"bib8-20230925","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1001\/archneur.55.12.1553","article-title":"Is essential tremor symmetric? 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