{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:14:15Z","timestamp":1761581655975},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Nucl Med"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>We report a case of Burkitt lymphoma with largely extranodal disease localizations at staging. Chemotherapy was given, thus obtaining a complete metabolic response in all previous disease sites as shown at a control PET, however associated to the appearance of new focal uptake areas in the liver; these findings were confirmed at US and MRI. Chemotherapy determined also neutropenia that was treated by filgrastim, followed by a prompt and important medullary response. Liver biopsy revealed extramedullary hematopoiesis, probably filgrastim induced. Filgrastim administration may cause false-positive findings in the liver at FDG PET.<\/jats:p>","DOI":"10.1097\/rlu.0000000000001998","type":"journal-article","created":{"date-parts":[[2018,2,4]],"date-time":"2018-02-04T22:59:27Z","timestamp":1517785167000},"page":"e130-e131","source":"Crossref","is-referenced-by-count":11,"title":["False-Positive 18F-FDG PET\/CT Due to Filgrastim That Induced Extramedullary Liver Hematopoiesis in a Burkitt Lymphoma"],"prefix":"10.1097","volume":"43","author":[{"given":"Anna Margherita","family":"Maffione","sequence":"first","affiliation":[{"name":"From the *Department of Nuclear Medicine, and \u2020Hematology Service, Santa Maria della Misericordia Hospital, Rovigo; \u2021Pathology Service, G.B. Rossi Hospital, Verona, Italy; and \u00a7Department of Radiology, University of Southern California, Los Angeles, CA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Rampin","sequence":"additional","affiliation":[{"name":"From the *Department of Nuclear Medicine, and \u2020Hematology Service, Santa Maria della Misericordia Hospital, Rovigo; \u2021Pathology Service, G.B. Rossi Hospital, Verona, Italy; and \u00a7Department of Radiology, University of Southern California, Los Angeles, CA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolini","family":"Rossella","sequence":"additional","affiliation":[{"name":"From the *Department of Nuclear Medicine, and \u2020Hematology Service, Santa Maria della Misericordia Hospital, Rovigo; \u2021Pathology Service, G.B. Rossi Hospital, Verona, Italy; and \u00a7Department of Radiology, University of Southern California, Los Angeles, CA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Pecori","sequence":"additional","affiliation":[{"name":"From the *Department of Nuclear Medicine, and \u2020Hematology Service, Santa Maria della Misericordia Hospital, Rovigo; \u2021Pathology Service, G.B. Rossi Hospital, Verona, Italy; and \u00a7Department of Radiology, University of Southern California, Los Angeles, CA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick M.","family":"Colletti","sequence":"additional","affiliation":[{"name":"From the *Department of Nuclear Medicine, and \u2020Hematology Service, Santa Maria della Misericordia Hospital, Rovigo; \u2021Pathology Service, G.B. Rossi Hospital, Verona, Italy; and \u00a7Department of Radiology, University of Southern California, Los Angeles, CA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Rubello","sequence":"additional","affiliation":[{"name":"From the *Department of Nuclear Medicine, and \u2020Hematology Service, Santa Maria della Misericordia Hospital, Rovigo; \u2021Pathology Service, G.B. Rossi Hospital, Verona, Italy; and \u00a7Department of Radiology, University of Southern California, Los Angeles, CA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"bib1-20230925","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1182\/blood.V88.8.2819.bloodjournal8882819","article-title":"Biologic and clinical effects of granulocyte colony-stimulating factor in normal individuals","volume":"88","year":"1996","journal-title":"Blood"},{"key":"bib2-20230925","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1182\/blood.V88.6.1907.bloodjournal8861907","article-title":"Filgrastim (r-metHuG-CSF): the first 10 years","volume":"88","year":"1996","journal-title":"Blood"},{"key":"bib3-20230925","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1097\/RLU.0b013e318187ee4d","article-title":"Paraspinal extramedullary hematopoiesis diagnosed using Tc-99m sulfur colloid","volume":"33","year":"2008","journal-title":"Clin Nucl Med"},{"key":"bib4-20230925","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1097\/RLU.0b013e3181abb7a6","article-title":"Extramedullary hematopoiesis within paravertebral masses demonstrating prominent sestamibi and thallium uptake","volume":"34","year":"2009","journal-title":"Clin Nucl Med"},{"key":"bib5-20230925","first-page":"950","article-title":"Effects of pegfilgrastim on normal biodistribution of 18 F-FDG: preclinical and clinical studies","volume":"47","year":"2006","journal-title":"J Nucl Med"},{"key":"bib6-20230925","first-page":"EIM03","article-title":"Abnormal positron emission tomography (PET) scan secondary to the use of hematopoietic growth factors","volume":"90","year":"2005","journal-title":"Haematologica"},{"key":"bib7-20230925","doi-asserted-by":"crossref","first-page":"e460","DOI":"10.1097\/MPH.0000000000000071","article-title":"Acute colchicine intoxication complicated with extramedullary hematopoiesis due to filgrastim in a child","volume":"36","year":"2014","journal-title":"J Pediatr Hematol Oncol"},{"key":"bib8-20230925","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/00003072-199905000-00004","article-title":"Fluorine-18 fluorodeoxyglucose splenic uptake from extramedullary hematopoiesis after granulocyte colony-stimulating factor stimulation","volume":"24","year":"1999","journal-title":"Clin Nucl Med"}],"container-title":["Clinical Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00003072-201804000-00034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T05:01:43Z","timestamp":1695618103000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00003072-201804000-00034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1097\/rlu.0000000000001998","relation":{},"ISSN":["1536-0229","0363-9762"],"issn-type":[{"value":"1536-0229","type":"electronic"},{"value":"0363-9762","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]}}}