{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:16:04Z","timestamp":1762161364909},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Nucl Med"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>A 38-year-old man with sigmoid colon cancer underwent a preoperative contrast-enhanced CT which incidentally revealed a modestly enhancing splenic mass. FDG PET\/CT showed mildly increased uptake in the splenic lesion in contrast to prominently increased uptake in the colonic tumor. In addition, the splenic mass demonstrated only slightly increased signal intensity in diffusion-weighted MRI, suggesting low probability of metastasis. Splenectomy nonetheless was performed at surgery of the colon cancer. The histopathologic examination showed aggregated lymphoid follicles with germinal centers in the splenic lesion and made the diagnosis of localized reactive lymphoid hyperplasia a rare benign lymphoid tumor.<\/jats:p>","DOI":"10.1097\/rlu.0000000000002020","type":"journal-article","created":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T19:21:27Z","timestamp":1519759287000},"page":"354-355","source":"Crossref","is-referenced-by-count":5,"title":["FDG PET\/CT Findings in a Localized Reactive Lymphoid Hyperplasia of the Spleen"],"prefix":"10.1097","volume":"43","author":[{"given":"Yoshiaki","family":"Ito","sequence":"first","affiliation":[{"name":"From the *Department of Radiology, National Hospital Organization Tokyo Medical Center; \u2020Department of Radiology, Keio University School of Medicine; and Departments of \u2021Surgery and \u00a7Pathology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadaki","family":"Nakahara","sequence":"additional","affiliation":[{"name":"From the *Department of Radiology, National Hospital Organization Tokyo Medical Center; \u2020Department of Radiology, Keio University School of Medicine; and Departments of \u2021Surgery and \u00a7Pathology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Nishihara","sequence":"additional","affiliation":[{"name":"From the *Department of Radiology, National Hospital Organization Tokyo Medical Center; \u2020Department of Radiology, Keio University School of Medicine; and Departments of \u2021Surgery and \u00a7Pathology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichi","family":"Shiraishi","sequence":"additional","affiliation":[{"name":"From the *Department of Radiology, National Hospital Organization Tokyo Medical Center; \u2020Department of Radiology, Keio University School of Medicine; and Departments of \u2021Surgery and \u00a7Pathology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Jinzaki","sequence":"additional","affiliation":[{"name":"From the *Department of Radiology, National Hospital Organization Tokyo Medical Center; \u2020Department of Radiology, Keio University School of Medicine; and Departments of \u2021Surgery and \u00a7Pathology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"bib1-20231021","first-page":"52","article-title":"Solid splenic masses: evaluation with 18F-FDG PET\/CT","volume":"46","year":"2005","journal-title":"J Nucl Med"},{"key":"bib2-20231021","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1097\/RLU.0b013e318217ae45","article-title":"Diagnosis of synchronous isolated splenic metastasis from lung adenocarcinoma: complementary role of FDG PET\/CT and diffusion-weighted MRI","volume":"36","year":"2011","journal-title":"Clin Nucl Med"},{"key":"bib3-20231021","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1097\/RLU.0000000000001805","article-title":"FDG PET\/CT in primary splenic angiosarcoma with diffuse involvement of the spleen","volume":"42","year":"2017","journal-title":"Clin Nucl Med"},{"key":"bib4-20231021","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1097\/RLU.0b013e3182a75ccc","article-title":"Enhanced CT and FDG PET\/CT findings of splenic hamartoma","volume":"39","year":"2014","journal-title":"Clin Nucl Med"},{"key":"bib5-20231021","doi-asserted-by":"crossref","first-page":"e465","DOI":"10.1097\/RLU.0b013e3182867581","article-title":"Distinctive PET\/CT features of splenic SANT","volume":"38","year":"2013","journal-title":"Clin Nucl Med"},{"key":"bib6-20231021","doi-asserted-by":"crossref","first-page":"e375","DOI":"10.1097\/RLU.0000000000000762","article-title":"18F-FDG PET\/CT findings in a splenic lymphangioma","volume":"40","year":"2015","journal-title":"Clin Nucl Med"},{"key":"bib7-20231021","doi-asserted-by":"crossref","first-page":"803","DOI":"10.2214\/AJR.13.11914","article-title":"Differentiation of malignant from benign focal splenic lesions: added value of diffusion-weighted MRI","volume":"203","year":"2014","journal-title":"AJR Am J Roentgenol"},{"key":"bib8-20231021","doi-asserted-by":"crossref","first-page":"85","DOI":"10.59566\/IJBS.2009.5085","article-title":"Primary tumors of the spleen","volume":"5","year":"2009","journal-title":"Int J Biomed Sci"},{"key":"bib9-20231021","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1097\/00000478-198306000-00009","article-title":"Localized reactive lymphoid hyperplasia of the spleen simulating malignant lymphoma. 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