{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T20:22:06Z","timestamp":1750537326003},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Nucl Med"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>A 62-year-old woman, with the history of breast and colorectal cancer, presented intermittent diplopia. A cerebellar lesion was revealed by <jats:sup>18<\/jats:sup>F-FDG PET-MRI without post-gadolinium enhancement, but with increased perfusion and strong <jats:sup>18<\/jats:sup>F-FDG uptake. The diagnosis of Cowden syndrome with PTEN gene mutation, linked to higher risk of neoplasia and occurrence of hamartomatous lesions characteristic of the Lhermitte-Duclos disease (LDD), was confirmed by genetic investigation.<\/jats:p>","DOI":"10.1097\/rlu.0000000000002248","type":"journal-article","created":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T21:16:54Z","timestamp":1535577414000},"page":"e355-e356","source":"Crossref","is-referenced-by-count":2,"title":["Increased 18F-FDG Uptake in Lhermitte-Duclos Disease With Cowden Syndrome Revealed by PET-MRI"],"prefix":"10.1097","volume":"43","author":[{"given":"Eve","family":"Piekarski","sequence":"first","affiliation":[{"name":"Nuclear Medicine, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadya","family":"Pyatigorskaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didier","family":"Dormont","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damien","family":"Galanaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aur\u00e9lie","family":"Kas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"bib1-20230925","article-title":"Lhermitte-Duclos disease in association with Cowden syndrome","volume":"22","year":"2016","journal-title":"Dermatol Online J"},{"key":"bib2-20230925","first-page":"217974","article-title":"Lhermitte-Duclos disease associated to Cowden syndrome: de novo diagnosis and management of these extremely rare syndromes in a patient","year":"2017","journal-title":"BMJ Case Rep"},{"key":"bib3-20230925","doi-asserted-by":"crossref","first-page":"e67","DOI":"10.1212\/WNL.0b013e3182815454","article-title":"Teaching neuroimages: MRI appearances of Lhermitte-Duclos disease","volume":"80","year":"2013","journal-title":"Neurology"},{"key":"bib4-20230925","article-title":"Lhermitte-Duclos disease","volume":"214235","year":"2015","journal-title":"BMJ Case Rep"},{"key":"bib5-20230925","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1097\/RLU.0b013e31815c4fa4","article-title":"FDG PET in Lhermitte-Duclos Disease","volume":"33","year":"2008","journal-title":"Clin Nucl Med"},{"key":"bib6-20230925","first-page":"824","article-title":"Lhermitte-Duclos disease; assessment with MR imaging, positron emission tomography, single-photon emission CT, and MR spectroscopy","volume":"22","year":"2001","journal-title":"Am J Neuroradiol"},{"key":"bib7-20230925","first-page":"404","article-title":"Fluorodeoxyglucose and methionine uptake in Lhermitte-Duclos disease: case report","volume":"50","year":"2002","journal-title":"Neurosurgery"},{"key":"bib8-20230925","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.mibio.2004.06.005","article-title":"Functional imaging in Lhermitte-Duclos disease","volume":"6","year":"2004","journal-title":"Mol Imaging Biol"},{"key":"bib9-20230925","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s11060-007-9355-x","article-title":"A case of Lhermitte-Duclos disease presenting high FDG uptake on FDG-PET\/CT","volume":"84","year":"2007","journal-title":"J Neurooncol"}],"container-title":["Clinical Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00003072-201810000-00029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T05:09:49Z","timestamp":1695618589000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00003072-201810000-00029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":9,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1097\/rlu.0000000000002248","relation":{},"ISSN":["1536-0229","0363-9762"],"issn-type":[{"value":"1536-0229","type":"electronic"},{"value":"0363-9762","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]}}}