{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T02:57:43Z","timestamp":1775530663819,"version":"3.50.1"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Clin Nucl Med"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Brown tumor is a reactive osteolytic lesion associated with hyperparathyroidism and an extremely rare form of a single lesion in the maxilla. We report the case of a 57-year-old woman with renal dysfunction, nasal obstruction, and hypercalcemia. MRI and CT revealed a huge osteolytic lesion in the maxilla. <jats:sup>18<\/jats:sup>F-FDG PET\/CT demonstrated marked FDG uptake within the mass and the lower-left lobe of the thyroid gland. <jats:sup>99m<\/jats:sup>Tc-methoxy-isobutyl-isonitrile scintigraphy suggested that this accumulation was a parathyroid adenoma. Parathyroid adenoma resection was performed, and the maxillary tumor was diagnosed as brown tumor. FDG PET\/CT was helpful in evaluating brown tumor and detecting parathyroid adenoma.<\/jats:p>","DOI":"10.1097\/rlu.0000000000003897","type":"journal-article","created":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T00:41:05Z","timestamp":1632530465000},"page":"236-238","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":12,"title":["18F-FDG-Detected Brown Tumor Confined to the Maxillary Bone With Parathyroid Adenoma"],"prefix":"10.1097","volume":"47","author":[{"given":"Emi","family":"Yamaga","sequence":"first","affiliation":[{"name":"Department of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Fujioka","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Asakage","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Miura","sequence":"additional","affiliation":[{"name":"Division of Surgical Pathology, Tokyo Medical and Dental University Hospital, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ukihide","family":"Tateishi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2021,9,23]]},"reference":[{"key":"bib1-20250621","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1007\/s002590050145","article-title":"Role of technetium-99m sestamibi scintimammography and contrast-enhanced magnetic resonance imaging for the evaluation of indeterminate mammograms","volume":"24","year":"1997","journal-title":"Eur J Nucl Med"},{"key":"bib2-20250621","first-page":"1166","article-title":"Noncardiac applications of hexakis(alkylisonitrile) technetium-99m complexes","volume":"31","year":"1990","journal-title":"J Nucl Med"},{"key":"bib3-20250621","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1097\/RLU.0000000000002380","article-title":"Synchronous metastatic breast carcinoma and parathyroid adenoma on 18F-FDG PET\/CT and 99mTc-sestamibi imaging","volume":"44","year":"2019","journal-title":"Clin Nucl Med"},{"key":"bib4-20250621","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1007\/s00423-016-1425-0","article-title":"Use of PET tracers for parathyroid localization: a systematic review and meta-analysis","volume":"401","year":"2016","journal-title":"Langenbecks Arch Surg"},{"key":"bib5-20250621","first-page":"230","article-title":"Brown tumor of the spine revealing secondary hyperparathyroidism. Report of a case","volume":"67","year":"2000","journal-title":"Joint Bone Spine"},{"key":"bib6-20250621","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1259\/dmfr\/19204128","article-title":"Primary hyperparathyroidism presenting as an exophytic mandibular mass","volume":"36","year":"2007","journal-title":"Dentomaxillofac Radiol"},{"key":"bib7-20250621","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1259\/dmfr\/81694583","article-title":"Brown tumour of the maxilla and mandible: a rare complication of tertiary hyperparathyroidism","volume":"38","year":"2009","journal-title":"Dentomaxillofac Radiol"},{"key":"bib8-20250621","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/scd.12284","article-title":"Brown tumor of the jaws as a manifestation of tertiary hyperparathyroidism: a literature review and case report","volume":"38","year":"2018","journal-title":"Spec Care Dentist"},{"key":"bib9-20250621","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1148\/radiology.219.3.r01ma08774","article-title":"FDG PET of primary benign and malignant bone tumors: standardized uptake value in 52 lesions","volume":"219","year":"2001","journal-title":"Radiology"}],"container-title":["Clinical Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/RLU.0000000000003897","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T20:06:52Z","timestamp":1750536412000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/RLU.0000000000003897"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,23]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1097\/rlu.0000000000003897","relation":{},"ISSN":["1536-0229","0363-9762"],"issn-type":[{"value":"1536-0229","type":"electronic"},{"value":"0363-9762","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9,23]]}}}