{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T14:18:24Z","timestamp":1777645104945,"version":"3.51.4"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Clin Nucl Med"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Acute cholecystitis typically exhibits intense FDG uptake of the gallbladder wall. Radiolabeled fibroblast activation protein inhibitor (FAPI) is considered as a potential alternative agent for tumor-specific imaging. We report <jats:sup>18<\/jats:sup>F-FDG and <jats:sup>68<\/jats:sup>Ga-FAPI-04 PET\/MR findings in a 44-year-old woman with acute exacerbation of chronic cholecystitis. The lesions show negative <jats:sup>18<\/jats:sup>F-FDG uptake but intense <jats:sup>68<\/jats:sup>Ga-FAPI-04 uptake in PET\/MR. This case highlights the imperative for nuclear medicine clinicians to exercise vigilance when evaluating gallbladder lesions exhibiting intense <jats:sup>68<\/jats:sup>Ga-FAPI-04 but negative <jats:sup>18<\/jats:sup>F-FDG uptake.<\/jats:p>","DOI":"10.1097\/rlu.0000000000005504","type":"journal-article","created":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T05:00:11Z","timestamp":1728882011000},"page":"349-351","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Negative 18F-FDG and Positive 68Ga-FAPI-04 Findings in a Patient With Acute Exacerbation of Chronic Cholecystitis"],"prefix":"10.1097","volume":"50","author":[{"given":"Na","family":"Qi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2024,10,14]]},"reference":[{"key":"bib1-20250303","first-page":"2416901","article-title":"Mirrizi syndrome and markedly elevated levels of carbohydrate antigen 19-9 in the absence of malignant disease","volume":"2017","year":"2017","journal-title":"Case Rep Gastrointest Med"},{"key":"bib2-20250303","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/01.rlu.0000191567.16067.83","article-title":"FDG PET imaging of acute cholecystitis","volume":"31","year":"2006","journal-title":"Clin Nucl Med"},{"key":"bib3-20250303","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1097\/01.RLU.0000048486.37794.8F","article-title":"Ring-like FDG uptake in acute cholecystitis","volume":"28","year":"2003","journal-title":"Clin Nucl Med"},{"key":"bib4-20250303","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1097\/01.rlu.0000132952.14515.9c","article-title":"Chronic cholecystitis detected by FDG-PET","volume":"29","year":"2004","journal-title":"Clin Nucl Med"},{"key":"bib5-20250303","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/RLU.0000000000004424","article-title":"Increased 68Ga-FAPI uptake in psammomatous meningioma in a patient with gallbladder cancer","volume":"48","year":"2023","journal-title":"Clin Nucl Med"},{"key":"bib6-20250303","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/s13139-022-00763-5","article-title":"The superiority of (68) Ga-FAPI-04 over (18)F-FDG in a case of gallbladder cancer","volume":"56","year":"2022","journal-title":"Nucl Med Mol Imaging"},{"key":"bib7-20250303","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1097\/RLU.0000000000005182","article-title":"Positive 18F-FDG and negative 68Ga-FAPI-04 findings in a patient with gallbladder adenocarcinoma","volume":"49","year":"2024","journal-title":"Clin Nucl Med"},{"key":"bib8-20250303","doi-asserted-by":"crossref","first-page":"e40","DOI":"10.1097\/RLU.0000000000004955","article-title":"FAPI uptake in gallbladder is it normal biodistribution?","volume":"49","year":"2024","journal-title":"Clin Nucl Med"},{"key":"bib9-20250303","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1097\/RLU.0000000000003621","article-title":"Increased 68Ga-FAPI uptake in chronic cholecystitis and degenerative osteophyte","volume":"46","year":"2021","journal-title":"Clin Nucl Med"},{"key":"bib10-20250303","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1097\/RLU.0000000000004248","article-title":"Xanthogranulomatous cholecystitis masquerading as gallbladder carcinoma on 68Ga-FAPI-04 PET","volume":"47","year":"2022","journal-title":"Clin Nucl Med"}],"container-title":["Clinical Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/RLU.0000000000005504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T18:00:41Z","timestamp":1741024841000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/RLU.0000000000005504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,14]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1097\/rlu.0000000000005504","relation":{},"ISSN":["1536-0229","0363-9762"],"issn-type":[{"value":"1536-0229","type":"electronic"},{"value":"0363-9762","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10,14]]}}}