{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T07:02:45Z","timestamp":1782889365551,"version":"3.54.5"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>\n                    We describe a 51-year-old man with cholangiocarcinoma of the common bile duct. Initially deemed nonmetastatic, he was a candidate for curative surgery and liver transplantation. However, during laparotomy, peritoneal seeding was discovered, necessitating omentectomy and lesion resection. Following chemotherapy, the patient underwent\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG PET\/CT for re-staging, revealing uptake in the primary tumor and a right iliac bone metastasis. Subsequently, FAPI-based scintigraphy using\n                    <jats:sup>99m<\/jats:sup>\n                    Tc-FAPI-46 as a novel conventional imaging agent demonstrated comparable uptake in both lesions. This case highlights the diagnostic potential of\n                    <jats:sup>99m<\/jats:sup>\n                    Tc-FAPI-46 SPECT\/CT as an alternative to\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG PET\/CT and\n                    <jats:sup>68<\/jats:sup>\n                    Ga-FAPI in cholangiocarcinoma, particularly in resource-limited settings.\n                  <\/jats:p>","DOI":"10.1097\/rlu.0000000000005877","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T06:00:09Z","timestamp":1747116009000},"page":"e695-e696","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Comparable Diagnostic Value of 99mTc-FAPI-46 SPECT\/CT and 18F-FDG PET\/CT in Cholangiocarcinoma: A Case Report"],"prefix":"10.1097","volume":"50","author":[{"given":"Nasrin","family":"Raeisi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amin","family":"Saber Tanha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitra","family":"Ghahraman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamran","family":"Aryana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atena","family":"Aghaee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,5,9]]},"reference":[{"key":"R1-20251114","doi-asserted-by":"crossref","first-page":"e281","DOI":"10.1097\/RLU.0000000000004641","article-title":"Role of 68Ga-FAPI PET\/CT in assessing hepatobiliary malignancies","volume":"48","author":"Rajaraman","year":"2023","journal-title":"Clin Nucl Med"},{"key":"R2-20251114","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1097\/RLU.0000000000005112","article-title":"68Ga-FAPI-04 PET\/CT for the evaluation of cholangiocarcinoma","volume":"49","author":"Zhang","year":"2024","journal-title":"Clin Nucl Med"},{"key":"R3-20251114","first-page":"693","article-title":"Cholangiocarcinoma: a comprehensive review and update guideline","volume":"10","author":"Nugraha","year":"2024","journal-title":"J Penelit Pendidik IPA"},{"key":"R4-20251114","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/RLU.0000000000000998","article-title":"Role of 18F-FDG PET\/CT imaging in intrahepatic cholangiocarcinoma","volume":"41","author":"Jiang","year":"2016","journal-title":"Clin Nucl Med"},{"key":"R5-20251114","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/RLU.0b013e3182867b99","article-title":"Implication of lymph node metastasis detected on 18F-FDG PET\/CT for surgical planning in patients with peripheral intrahepatic cholangiocarcinoma","volume":"39","author":"Park","year":"2014","journal-title":"Clin Nucl Med"},{"key":"R6-20251114","doi-asserted-by":"crossref","first-page":"e106","DOI":"10.1097\/RLU.0b013e318266f402","article-title":"The clinical value of dual\u2013time point 18F-FDG PET\/CT for differentiating extrahepatic cholangiocarcinoma from benign disease","volume":"38","author":"Choi","year":"2013","journal-title":"Clin Nucl Med"},{"key":"R7-20251114","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1097\/RLU.0b013e3182291a64","article-title":"The value of F-18 FDG PET in patients with primary sclerosing cholangitis and cholangiocarcinoma using visual and semiquantitative analysis","volume":"36","author":"Alkhawaldeh","year":"2011","journal-title":"Clin Nucl Med"},{"key":"R8-20251114","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1097\/RLU.0000000000004438","article-title":"Comparison of the detection performance between FAP and FDG PET\/CT in various cancers","volume":"48","author":"Chang","year":"2023","journal-title":"Clin Nucl Med"},{"key":"R9-20251114","doi-asserted-by":"crossref","first-page":"e122","DOI":"10.1097\/RLU.0000000000005554","article-title":"Utilizing 99mTc-FAPI-46 SPECT\/CT in detection of peritoneal carcinomatosis in gastric poorly differentiated adenocarcinoma","volume":"50","author":"Raeisi","year":"2024","journal-title":"Clin Nucl Med"},{"key":"R10-20251114","doi-asserted-by":"crossref","first-page":"e691","DOI":"10.1097\/RLU.0000000000005522","article-title":"99mTc-PSMA and 99mTc-FAPI-46 uptake in pulmonary lymphangitic carcinomatosis","volume":"49","author":"Raeisi","year":"2024","journal-title":"Clin Nucl Med"},{"key":"R11-20251114","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1097\/RLU.0000000000004802","article-title":"68Ga-FAPI PET\/CT imaging","volume":"48","author":"Al-Ibraheem","year":"2023","journal-title":"Clin Nucl Med"},{"key":"R12-20251114","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1097\/RLU.0000000000004602","article-title":"Are we approaching a change in paradigm in PET\/CT imaging of solid gastrointestinal (or digestive) tract tumors with the clinical application of FAPI imaging?","volume":"48","author":"Delgado Bolton","year":"2023","journal-title":"Clin Nucl Med"}],"container-title":["Clinical Nuclear 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