{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T11:15:56Z","timestamp":1789125356497,"version":"build-2803163510"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>\n                    We present a 54-year-old man with hepatocellular carcinoma (HCC) presenting with diffuse bone pain 6 months postradiofrequency ablation.\n                    <jats:sup>99m<\/jats:sup>\n                    Tc-FAPI-46 SPECT\/CT was performed to evaluate disease extent, confirming locally active primary HCC and revealing widespread FAPI-avid bone metastases. Considering the low performance of FDG PET\/CT scan in hepatocellular carcinoma, this case highlights\n                    <jats:sup>99m<\/jats:sup>\n                    Tc- FAPI-46 Scintigraphy as a highly sensitive, accessible radiopharmaceutical for comprehensive HCC restaging, offering excellent visualization of stroma-rich extrahepatic lesions and critical insights into advanced tumor biology.\n                  <\/jats:p>","DOI":"10.1097\/rlu.0000000000006680","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T11:00:51Z","timestamp":1789124451000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Utility of 99mTc-FAPI-46 SPECT\/CT in Restaging Hepatocellular Carcinoma"],"prefix":"10.1097","author":[{"given":"Faeze","family":"Rabani","sequence":"first","affiliation":[{"name":"Nuclear Medicine Research 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quantitative SPECT\/CT with [68Ga] Ga-FAPI-04 PET\/CT in patients with gastrointestinal tumors","volume":"21","author":"Zhou","year":"2024","journal-title":"Mol Pharm"},{"key":"R7-20260911","doi-asserted-by":"crossref","first-page":"3877","DOI":"10.1007\/s00259-026-07804-7","article-title":"Assessment of liver fibrosis and tumor burden in hepatocellular carcinoma using [(18)F]AlF-NOTA-FAPI-04 PET\/CT: a prospective study","volume":"53","author":"Wang","year":"2026","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"R8-20260911","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1097\/RLU.0000000000006345","article-title":"Radioactive distribution patterns of [68Ga]Ga-FAPI-04 in primary hepatocellular carcinoma","volume":"51","author":"Zhu","year":"2026","journal-title":"Clin Nucl Med"},{"key":"R9-20260911","doi-asserted-by":"crossref","first-page":"e274","DOI":"10.1097\/RLU.0000000000006045","article-title":"FAPI-negative but FDG-avid hepatocellular carcinoma with extensive steatosis","volume":"51","author":"Lv","year":"2026","journal-title":"Clin Nucl Med"},{"key":"R10-20260911","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.2967\/jnumed.123.265712","article-title":"Comparison of baseline (68)Ga-FAPI and (18)F-FDG PET\/CT for prediction of response and clinical outcome in patients with unresectable hepatocellular carcinoma treated with PD-1 inhibitor and lenvatinib","volume":"64","author":"Wu","year":"2023","journal-title":"J Nucl Med"}],"container-title":["Clinical Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/RLU.0000000000006680","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T11:00:52Z","timestamp":1789124452000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1097\/RLU.0000000000006680"}},"subtitle":["A Case 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