{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:06:14Z","timestamp":1791410774735,"version":"4.3.3"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1097\/rlu.0b013e3182177389","type":"journal-article","created":{"date-parts":[[2011,8,6]],"date-time":"2011-08-06T05:37:42Z","timestamp":1312609062000},"page":"743-748","source":"Crossref","is-referenced-by-count":82,"title":["Increased Right Ventricular Glucose Metabolism in Patients With Pulmonary Arterial Hypertension"],"prefix":"10.1097","volume":"36","author":[{"given":"Mehmet Mustafa","family":"Can","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cihangir","family":"Kaymaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim Halil","family":"Tanboga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hacer Ceren","family":"Tokgoz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nesrin","family":"Canpolat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdem","family":"Turkyilmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenan","family":"Sonmez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nihal","family":"Ozdemir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-1-20210204","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1164\/ajrccm.167.9.950","article-title":"ATS statement on six-minute walk test.","volume":"167","author":"Brooks","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"key":"R2-1-20210204","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1056\/NEJM199207093270203","article-title":"The effect of high doses of calcium channel blockers on survival in primary pulmonary hypertension.","volume":"327","author":"Rich","year":"1992","journal-title":"N Engl J Med"},{"key":"R3-1-20210204","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.1161\/CIRCULATIONAHA.104.488486","article-title":"Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension.","volume":"111","author":"Sitbon","year":"2005","journal-title":"Circulation"},{"key":"R4-1-20210204","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1161\/01.CIR.102.22.2781","article-title":"Primary pulmonary hypertension: a vascular biology and translational research \u201cWork in progress.\u201d","volume":"102","author":"Archer","year":"2000","journal-title":"Circulation"},{"key":"R5-1-20210204","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1126\/science.3975623","article-title":"Regional myocardial substrate uptake in hypertensive rats: a quantitative autoradiographic measurement.","volume":"227","author":"Yonekura","year":"1985","journal-title":"Science"},{"key":"R6-1-20210204","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1161\/01.HYP.11.5.416","article-title":"Effects of moderate hypertension on cardiac function and metabolism in the rabbit.","volume":"11","author":"Taegtmeyer","year":"1988","journal-title":"Hypertension"},{"key":"R7-1-20210204","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1161\/01.CIR.81.4.1353","article-title":"Effects of long-term pressure overload on regional myocardial glucose and free fatty acid uptake in rats: a quantitative autoradiographic study.","volume":"81","author":"Kagaya","year":"1990","journal-title":"Circulation"},{"key":"R8-1-20210204","first-page":"H2090","article-title":"Control of oxidative metabolism in volume-overloaded rat hearts: effects of different lipid substrates.","volume":"266","author":"Ben Cheikh","year":"1994","journal-title":"Am J Physiol"},{"key":"R9-1-20210204","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1161\/CIRCULATIONAHA.106.632208","article-title":"Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanism of right heart failure.","volume":"114","author":"Voelkel","year":"2006","journal-title":"Circulation"},{"key":"R10-1-20210204","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1152\/ajplegacy.1963.205.6.1203","article-title":"Effect of fasting on glucose and palmitate metabolism of perfuse rat heart.","volume":"205","author":"Opie","year":"1963","journal-title":"Am J Physiol"},{"key":"R11-1-20210204","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1172\/JCI112820","article-title":"Myocardial metabolism of free fatty acids: studies with 14C labeled substrates in humans.","volume":"79","author":"Wisnecki","year":"1987","journal-title":"J Clin Invest"},{"key":"R12-1-20210204","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1007\/s00259-008-0888-9","article-title":"Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage.","volume":"35","author":"Busk","year":"2008","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"R13-1-20210204","doi-asserted-by":"crossref","first-page":"5198","DOI":"10.1158\/0008-5472.CAN-08-0555","article-title":"The Warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation.","volume":"68","author":"Samudio","year":"2008","journal-title":"Cancer Res"},{"key":"R14-1-20210204","first-page":"H1068","article-title":"Fatty acid oxidation and mechanical performance of volume overloaded rat hearts.","volume":"262","author":"El-Alaoui-Talibi","year":"1992","journal-title":"Am J Physiol"},{"key":"R15-1-20210204","first-page":"H742","article-title":"Contribution of oxidative metabolism and glycolysis ATP production in hypertrophied hearts.","volume":"267","author":"Allard","year":"1994","journal-title":"Am J Physiol"},{"key":"R16-1-20210204","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1016\/S0735-1097(99)00063-7","article-title":"Volume overload hypertrophy of the newborn heart slows the maturation of enzymes involved in the regulation of fatty acid metabolism.","volume":"33","author":"Kantor","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"R17-1-20210204","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1164\/rccm.200709-1369PP","article-title":"The cancer paradigm of severe pulmonary arterial hypertension.","volume":"178","author":"Rai","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"issue":"suppl 1","key":"R18-1-20210204","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/j.jacc.2009.04.018","article-title":"Cellular and molecular basis of pulmonary arterial hypertension.","volume":"54","author":"Morrell","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"R19-1-20210204","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.mvr.2004.06.001","article-title":"Cellular and molecular mechanisms of pulmonary vascular remodeling: role in the development of pulmonary hypertension.","volume":"68","author":"Mandegar","year":"2004","journal-title":"Microvasc Res"},{"key":"R20-1-20210204","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1164\/ajrccm.166.1.at1102","article-title":"ATS statement: guidelines for the six-minute walk test.","volume":"166","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"R21-1-20210204","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/0735-1097(92)90295-X","article-title":"Comparison of the effects of adenosine and nifedipine in pulmonary hypertension.","volume":"19","author":"Schrader","year":"1992","journal-title":"J Am Coll Cardiol"},{"key":"R22-1-20210204","first-page":"357","article-title":"New index of combined systolic and diastolic myocardial performance: a simple and reproducible measure of cardiac function\u2014a study in normals and dilated cardiomyopathy.","volume":"26","author":"Tei","year":"1995","journal-title":"J Cardiol"},{"key":"R23-1-20210204","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1161\/01.CIR.91.6.1814","article-title":"Myocardial high-energy phosphate and substrate metabolism in swine with moderate left ventricular hypertrophy.","volume":"91","author":"Massie","year":"1995","journal-title":"Circulation"},{"key":"R24-1-20210204","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/0140-6736(91)91838-L","article-title":"Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31 P magnetic resonance spectroscopy.","volume":"338","author":"Conway","year":"1991","journal-title":"Lancet"},{"key":"R25-1-20210204","first-page":"1676","article-title":"Impaired regional fatty acid uptake and systolic dysfunction in hypertrophied right ventricle.","volume":"39","author":"Nagaya","year":"1988","journal-title":"J Nucl Med"},{"key":"R26-1-20210204","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/BF00258103","article-title":"New radioiodinated methyl branched fatty acids for cardiac studies.","volume":"12","author":"Knapp","year":"1986","journal-title":"Eur J Nucl Med"},{"key":"R27-1-20210204","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/BF00258104","article-title":"Structurally modified fatty acids: clinical potential as tracers of metabolism.","volume":"12","author":"Dudezak","year":"1986","journal-title":"Eur J Nucl Med"},{"key":"R28-1-20210204","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/BF00941855","article-title":"Iodine-123-labeled fatty acids for myocardial single-photon emission tomography: current status and future perspectives.","volume":"22","author":"Knapp","year":"1995","journal-title":"Eur J Nucl Med"},{"key":"R29-1-20210204","first-page":"1131","article-title":"Basic studies on I-123-beta-methyl-p-iodophenylpentadecanoic acid (BMIPP), for myocardial functional diagnosis: effect of beta-oxidation inhibitor.","volume":"25","author":"Fujibayashi","year":"1988","journal-title":"Jpn J Nucl Med"},{"key":"R30-1-20210204","first-page":"1818","article-title":"Myocardial accumulation of iodinated beta-methyl-branched fatty acid analogue, iodine-125-15-(p-iodophenyl)-3-(R,S) methyl pentadecanoic acid (BMIPP), in relation to ATP content.","volume":"31","author":"Fujibayashi","year":"1990","journal-title":"J Nucl Med"},{"key":"R31-1-20210204","first-page":"69","article-title":"Myocardial uptake of 125-I-BMIPP in rats treated with Adriamycin.","volume":"26","author":"Ogata","year":"1989","journal-title":"Jpn J Nucl Med"},{"key":"R32-1-20210204","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1161\/01.CIR.101.14.1686","article-title":"Long-term right ventricular volume overload increases myocardial fluorodeoxyglucose uptake in the interventricular septum in patients with atrial septal defect.","volume":"101","author":"Otani","year":"2000","journal-title":"Circulation"},{"key":"R33-1-20210204","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1161\/01.CIR.92.4.819","article-title":"Pressure and volume loading of the right ventricle have opposite effect on the left ventricular ejection fraction.","volume":"92","author":"Louie","year":"1995","journal-title":"Circulation"},{"key":"R34-1-20210204","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1097\/RLU.0b013e31817082ad","article-title":"Pulmonary hypertension findings detected by F-18 FDG PET scan.","volume":"33","author":"Abikhzer","year":"2008","journal-title":"Clin Nucl Med"},{"key":"R35-1-20210204","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1097\/01.rlu.0000259624.76063.65","article-title":"Avid FDG uptake in the right ventricle coupled with enhanced intercostal muscle hypermetabolism in pneumoconiosis.","volume":"32","author":"Basu","year":"2007","journal-title":"Clin Nucl Med"}],"container-title":["Clinical Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/RLU.0b013e3182177389","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T20:23:56Z","timestamp":1786047836000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00003072-201109000-00001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":35,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/rlu.0b013e3182177389","relation":{},"ISSN":["0363-9762"],"issn-type":[{"value":"0363-9762","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}