{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T18:24:53Z","timestamp":1748283893369},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec>\n            <jats:title>Abstract<\/jats:title>\n            <jats:p>Mesenchymal chondrosarcoma (MCS) is a rare tumor in the orbit. Although optic nerve displacement is a common finding in intraorbital MCS, optic nerve tissue involvement in tumor has rarely been reported in huge tumors associated with intracranial extension. Herein the authors report a patient with MCS involving optic nerve tissue without intracranial extension. A 59-year-old woman with a 2-month history of progressive proptosis and normal vision presented to us. Computed tomography revealed a clearly outlined heterogeneous mass with calcified foci in its center, which was attached to the optic nerve, magnetic resonance imaging showed the mass to be isointense to gray matter on T1- and T2-weighted images. She underwent lateral orbitotomy and partial tumor excision. Histopathologic study confirmed MCS. She refused exenteration till 1 year but the tumor recurred and her vision decreased to no light perception. Then exenteration was performed with obtaining free margin and she is now free of tumor after 6 months without radiotherapy or chemotherapy. Mesenchymal chondrosarcoma must be differentiated from more common calcified tumors attached to optic nerve like meningioma.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/scs.0000000000004635","type":"journal-article","created":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T19:35:10Z","timestamp":1527795310000},"page":"e591-e594","source":"Crossref","is-referenced-by-count":5,"title":["Mesenchymal Chondrosarcoma of the Orbit Attached to the Optic Nerve"],"prefix":"10.1097","volume":"29","author":[{"given":"Abbas","family":"Bagheri","sequence":"first","affiliation":[{"name":"Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences"},{"name":"Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Abbaszadeh","sequence":"additional","affiliation":[{"name":"Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences"},{"name":"Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peyman","family":"Torbati","sequence":"additional","affiliation":[{"name":"Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences"},{"name":"Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mozhgan","family":"Rezaei Kanavi","sequence":"additional","affiliation":[{"name":"Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences"},{"name":"Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-20230824","doi-asserted-by":"crossref","first-page":"292147","DOI":"10.1155\/2012\/292147","article-title":"Primary orbital mesenchymal chondrosarcoma: case report and review of literature","volume":"2012","author":"Herrera","year":"2012","journal-title":"Case Rep Med"},{"key":"R2-20230824","first-page":"416","article-title":"Orbito-cranial mesenchymal chondrosarcoma in a young female: a rare case report","volume":"4","author":"Sharma","year":"2016","journal-title":"Case Rep"},{"key":"R3-20230824","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1002\/1097-0142(195911\/12)12:6<1142::AID-CNCR2820120610>3.0.CO;2-D","article-title":"Unusual benign and malignant chondroid tumors of bone. A survey of some mesenchymal cartilage tumors and malignant chondroblastic tumors including a few multicentric ones, as well as many atypical benign chondroblastomas and chondromyxoid fibromas","volume":"12","author":"Lightenstein","year":"1959","journal-title":"Cancer"},{"key":"R4-20230824","doi-asserted-by":"crossref","first-page":"747","DOI":"10.2106\/00004623-196446040-00004","article-title":"Mesenchymal chondrosarcoma","volume":"46","author":"Dowling","year":"1964","journal-title":"J Bone Joint Surg Am"},{"key":"R5-20230824","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s10792-007-9184-0","article-title":"Primary orbital mesenchymal chondrosarcoma: a case report and literature review","volume":"29","author":"Odashiro","year":"2009","journal-title":"Int Ophthalmol"},{"key":"R6-20230824","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1076\/orbi.20.1.63.2646","article-title":"Mesenchymal chondrosarcoma of the orbit: a clinicopathological study","volume":"1","author":"Kashyap","year":"2001","journal-title":"Orbit"},{"key":"R7-20230824","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.crad.2011.10.004","article-title":"Mesenchymal chondrosarcoma of the orbit: CT and MRI findings","volume":"67","author":"Yang","year":"2012","journal-title":"Clin Radiol"},{"key":"R8-20230824","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1097\/IOP.0b013e3181a142fc","article-title":"Mesenchymal chondrosarcoma of the orbit: a unique- radiologic pathologic correlation","volume":"25","author":"Font","year":"2009","journal-title":"Ophthal Plast Reconstr Surg"},{"key":"R9-20230824","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.clinimag.2009.12.002","article-title":"An unusual case of primary mesenchymal chondrosarcoma in orbit with intracranial extension","volume":"34","author":"Liu","year":"2010","journal-title":"Clin Imaging"},{"key":"R10-20230824","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1080\/01676830601169007","article-title":"Mesenchymal chondrosarcoma of the orbit: a report of two cases and review of the literature","volume":"27","author":"Kaur","year":"2008","journal-title":"Orbit"},{"key":"R11-20230824","doi-asserted-by":"crossref","first-page":"747","DOI":"10.2176\/nmc.52.747","article-title":"Mesenchymal chondrosarcoma of the orbit-case report","volume":"52","author":"Hanakita","year":"2012","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"R12-20230824","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1097\/01.iop.0000229691.87499.99","article-title":"Mesenchymal chondrosarcoma of the orbit","volume":"22","author":"Angotti-Neto","year":"2006","journal-title":"Ophthal Plast Reconstr Surg"},{"key":"R13-20230824","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3109\/01676831003664327","article-title":"A challenging case of primary orbital mesenchymal chondrosarcoma","volume":"29","author":"Bonavolonta","year":"2010","journal-title":"Orbit"},{"key":"R14-20230824","doi-asserted-by":"crossref","first-page":"126","DOI":"10.3109\/01676830.2011.638097","article-title":"Mesenchymal chondrosarcoma of the orbit","volume":"31","author":"Patel","year":"2012","journal-title":"Orbit"},{"key":"R15-20230824","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/j.ophtha.2003.12.026","article-title":"Congenital mesenchymal chondrosarcoma of the orbit: case report and review of the literature","volume":"111","author":"Tuncer","year":"2004","journal-title":"Ophthalmology"},{"key":"R16-20230824","first-page":"296","article-title":"Primary mesenchymal chondrosarcoma of the orbit: case report and review of the literature","volume":"39","author":"Trzcihska-Dabrowska","year":"1994","journal-title":"Neuroradiology"},{"key":"R17-20230824","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1111\/j.1365-2354.2008.01028.x","article-title":"Mesenchymal chondrosarcoma of the orbit: an unusual site for a rare tumor","volume":"19","author":"Razak","year":"2010","journal-title":"Eur J Cancer Care"}],"container-title":["Journal of Craniofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00001665-201809000-00099","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T21:11:53Z","timestamp":1692911513000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00001665-201809000-00099"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1097\/scs.0000000000004635","relation":{},"ISSN":["1049-2275","1536-3732"],"issn-type":[{"value":"1049-2275","type":"print"},{"value":"1536-3732","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9]]}}}