{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T19:31:37Z","timestamp":1790969497314,"version":"4.1.0"},"reference-count":47,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,4]]},"DOI":"10.1097\/shk.0b013e3181ffff0e","type":"journal-article","created":{"date-parts":[[2010,10,8]],"date-time":"2010-10-08T11:41:17Z","timestamp":1286538077000},"page":"396-402","source":"Crossref","is-referenced-by-count":44,"title":["Inflammatory Effects of Hypothermia and Inhaled H2S During Resuscitated, Hyperdynamic Murine Septic Shock"],"prefix":"10.1097","volume":"35","author":[{"given":"Florian","family":"Wagner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Weber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Stahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus W.","family":"Kn\u00f6ferl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Huber-Lang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel H.","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Asfar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Calzia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"Senftleben","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Gebhard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Georgieff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Radermacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladislava","family":"Hysa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-12-20210213","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.cyto.2005.06.008","article-title":"Effects of hypothermia and re-warming on the inflammatory response in a murine multiple hit model of trauma.","volume":"31","author":"Hildebrand","year":"2005","journal-title":"Cytokine"},{"key":"R2-12-20210213","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/ALN.0b013e3181de7107","article-title":"Inhaled hydrogen sulfide protects against ventilator-induced lung injury.","volume":"113","author":"Faller","year":"2010","journal-title":"Anesthesiology"},{"key":"R3-12-20210213","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/01.CCM.0000151049.19253.54","article-title":"Correction of perioperative hypothermia decreases experimental sepsis mortality by modulating the inflammatory response.","volume":"33","author":"Xiao","year":"2005","journal-title":"Crit Care Med"},{"key":"R4-12-20210213","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/PCC.0b013e3181b01042","article-title":"Hypothermia increases interleukin-6 and interleukin-10 in juvenile endotoxemic mice.","volume":"11","author":"Stewart","year":"2010","journal-title":"Pediatr Crit Care Med"},{"key":"R5-12-20210213","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1126\/science.1108581","article-title":"H2S induces a suspended animation-like state in mice.","volume":"308","author":"Blackstone","year":"2005","journal-title":"Science"},{"key":"R6-12-20210213","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1097\/SHK.0b013e31802e27a0","article-title":"Suspended animation-like state protects mice from lethal hypoxia.","volume":"27","author":"Blackstone","year":"2007","journal-title":"Shock"},{"key":"R7-12-20210213","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1681\/ASN.2008121269","article-title":"Hydrogen sulfide-induced hypometabolism prevents renal ischemia\/reperfusion injury.","volume":"20","author":"Bos","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"R8-12-20210213","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1186\/cc7700","article-title":"Hydrogen sulphide-the \"third\" gaseous transmitter: applications for critical care.","volume":"13","author":"Wagner","year":"2009","journal-title":"Crit Care"},{"key":"R9-12-20210213","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1089\/ars.2009.2899","article-title":"The effect of hydrogen sulphide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages.","volume":"12","author":"Whiteman","year":"2010","journal-title":"Antioxid Redox Singal"},{"key":"R10-12-20210213","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1096\/fj.04-3583fje","article-title":"Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.","volume":"19","author":"Li","year":"2005","journal-title":"FASEB J"},{"key":"R11-12-20210213","doi-asserted-by":"crossref","first-page":"L896","DOI":"10.1152\/ajplung.00053.2006","article-title":"Role of substance P in hydrogen sulfide-induced pulmonary inflammation in mice.","volume":"291","author":"Bhatia","year":"2006","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"R12-12-20210213","doi-asserted-by":"crossref","first-page":"L1193","DOI":"10.1152\/ajplung.00489.2005","article-title":"Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse.","volume":"290","author":"Zhang","year":"2006","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"R13-12-20210213","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1189\/jlb.0407237","article-title":"Endogenous hydrogen sulfide regulates leukocyte trafficking in cecal ligation and puncture-induced sepsis.","volume":"82","author":"Zhang","year":"2007","journal-title":"J Leukoc Biol"},{"key":"R14-12-20210213","doi-asserted-by":"crossref","first-page":"L960","DOI":"10.1152\/ajplung.00388.2006","article-title":"Hydrogen sulfide acts as an inflammatory mediator in cecal ligation and puncture-induced sepsis in mice by upregulating the production of cytokines and chemokines via NF-B.","volume":"292","author":"Zhang","year":"2007","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"R15-12-20210213","doi-asserted-by":"crossref","first-page":"4153","DOI":"10.4049\/jimmunol.179.6.4153","article-title":"Hydrogen sulfide up-regulates substance P in polymicrobial sepsis-associated lung injury.","volume":"79","author":"Zhang","year":"2007","journal-title":"J Immunol"},{"key":"R16-12-20210213","doi-asserted-by":"crossref","first-page":"4320","DOI":"10.4049\/jimmunol.181.6.4320","article-title":"Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.","volume":"181","author":"Zhang","year":"2008","journal-title":"J Immunol"},{"key":"R17-12-20210213","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1097\/CCM.0b013e3181c0df00","article-title":"Hydrogen sulfide promotes transient receptor potential vanilloid 1-mediated neurogenic inflammation in polymicrobial sepsis.","volume":"38","author":"Ang","year":"2010","journal-title":"Crit Care Med"},{"key":"R18-12-20210213","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1164\/rccm.200907-1145OC","article-title":"Hydrogen sulfide improves neutrophil migration and survival in sepsis via K+ATP-channel activation.","volume":"182","author":"Spiller","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"R19-12-20210213","doi-asserted-by":"crossref","first-page":"417","DOI":"10.2119\/molmed.2010.00027","article-title":"Role of hydrogen sulfide in severe burn injury-induced inflammation in the mouse.","volume":"16","author":"Zhang","year":"2010","journal-title":"Mol Med"},{"key":"R20-12-20210213","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1042\/CS20080021","article-title":"Protective effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalation.","volume":"115","author":"Esechie","year":"2008","journal-title":"Clin Sci (Lond)"},{"key":"R21-12-20210213","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/1476-9255-6-35","article-title":"Effects of hydrogen sulfide on inflammation in caerulein-induced acute pancreatitis.","volume":"6","author":"Sidhapuriwala","year":"2009","journal-title":"J Inflamm"},{"key":"R22-12-20210213","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1097\/SHK.0b013e31816a6e0f","article-title":"The effect of superoxide dismutase overexpression on hepatic gluconeogenesis and whole-body glucose oxidation during resuscitated normotensive murine septic shock.","volume":"30","author":"Simkova","year":"2008","journal-title":"Shock"},{"key":"R23-12-20210213","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1097\/CCM.0b013e3181b9ed2e","article-title":"Cardiac and metabolic effects of hypothermia and inhaled H2S in anesthetized and ventilated mice.","volume":"38","author":"Baumgart","year":"2010","journal-title":"Crit Care Med"},{"key":"R24-12-20210213","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1097\/ALN.0b013e318167af0d","article-title":"Inhaled hydrogen sulfide: a rapidly reversible inhibitor of cardiac and metabolic function in the mouse.","volume":"108","author":"Volpato","year":"2008","journal-title":"Anesthesiology"},{"key":"R25-12-20210213","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1164\/rccm.200611-1743OC","article-title":"Fas-induced pulmonary apoptosis and inflammation during acute lung injury.","volume":"176","author":"Perl","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"R26-12-20210213","doi-asserted-by":"crossref","first-page":"8083","DOI":"10.4049\/jimmunol.179.12.8083","article-title":"Enhancement of NF-B activation in lymphocytes prevents T cell apoptosis and improves survival in murine sepsis.","volume":"179","author":"Groesdonk","year":"2007","journal-title":"J Immunol"},{"key":"R27-12-20210213","first-page":"3565","article-title":"Opposite role of 2- and -adrenoceptors in the modulation of interleukin-10 production in endotoxaemic mice.","volume":"11","author":"Szelenyi","year":"2000","journal-title":"Neuro Rep"},{"key":"R28-12-20210213","doi-asserted-by":"crossref","first-page":"R11","DOI":"10.1186\/cc7709","article-title":"Central sympatholytics prolong survival in experimental sepsis.","volume":"13","author":"Hofer","year":"2009","journal-title":"Crit Care"},{"key":"R29-12-20210213","doi-asserted-by":"crossref","first-page":"861","DOI":"10.4049\/jimmunol.154.2.861","article-title":"Chlorpromazine amplifies macrophage-dependent IL-10 production in vivo.","volume":"154","author":"Tarazona","year":"1995","journal-title":"J Immunol"},{"key":"R30-12-20210213","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/00005373-200002000-00003","article-title":"Chlorpromazine modulates cytokine expression in the liver and lung after burn injury and endotoxemia.","volume":"48","author":"Clancy","year":"2000","journal-title":"J Trauma"},{"key":"R31-12-20210213","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1097\/00000542-199402000-00020","article-title":"Ketamine suppresses endotoxin-induced tumor necrosis factor alpha production in mice.","volume":"80","author":"Takenaka","year":"1994","journal-title":"Anesthesiology"},{"key":"R32-12-20210213","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1097\/00000542-199811000-00023","article-title":"Endotoxin-stimulated cytokine response in cultured human whole blood.","volume":"89","author":"Larsen","year":"1998","journal-title":"Anesthesiology"},{"key":"R33-12-20210213","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1097\/CCM.0b013e318169f30e","article-title":"Effects of respiratory rate on ventilator-induced lung injury at constant PacO2 in a mouse model of normal lung.","volume":"36","author":"Vaporidi","year":"2008","journal-title":"Crit Care Med"},{"key":"R34-12-20210213","doi-asserted-by":"crossref","first-page":"L379","DOI":"10.1152\/ajplung.00010.2008","article-title":"Animal models of acute lung injury.","volume":"295","author":"Matute-Bello","year":"2008","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"R35-12-20210213","doi-asserted-by":"crossref","first-page":"R136","DOI":"10.1186\/cc5050","article-title":"Mechanical ventilation interacts with endotoxemia to induce extrapulmonary organ dysfunction.","volume":"10","author":"O'Mahoney","year":"2006","journal-title":"Critical Care"},{"key":"R36-12-20210213","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.2174\/092986706777584997","article-title":"Catecholamines: physiological immunomodulators during health and illness.","volume":"13","author":"Oberbeck","year":"2006","journal-title":"Curr Med Chem"},{"key":"R37-12-20210213","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1006\/jsre.1997.5135","article-title":"Heme oxygenase-dependent carbon monoxide production is a hepatic adaptive response to sepsis.","volume":"71","author":"Downard","year":"1997","journal-title":"J Surg Res"},{"key":"R38-12-20210213","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1172\/JCI32730","article-title":"Heme oxygenase-1-derived carbon monoxide enhances the host defense response to microbial sepsis in mice.","volume":"118","author":"Chung","year":"2008","journal-title":"J Clin Invest"},{"key":"R39-12-20210213","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.freeradbiomed.2006.03.021","article-title":"Hydrogen sulfide inhibits nitric oxide production and nuclear factor-B via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide.","volume":"41","author":"Oh","year":"2006","journal-title":"Free Radic Biol Med"},{"key":"R40-12-20210213","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1016\/j.yexcr.2010.02.044","article-title":"Hydrogen sulfide induces ICAM-1 expression and neutrophil adhesion to caerulein-treated pancreatic acinar cells through NF-kappaB and Src-family kinases pathway.","volume":"316","author":"Tamizhselvi","year":"2010","journal-title":"Exp Cell Res"},{"key":"R41-12-20210213","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1124\/jpet.109.150532","article-title":"Effect of hydrogen sulfide on the phosphatidylinositol 3-kinase-protein kinase B pathway and on caerulein-induced cytokine production in isolated mouse pancreatic acinar cells.","volume":"329","author":"Tamizhselvi","year":"2009","journal-title":"J Pharmacol Exp Ther"},{"key":"R42-12-20210213","doi-asserted-by":"crossref","first-page":"R108","DOI":"10.1186\/cc6995","article-title":"Inflammatory and transcriptional roles of poly (ADP-ribose) polymerase in ventilator-induced lung injury.","volume":"12","author":"Kim","year":"2008","journal-title":"Crit Care"},{"key":"R43-12-20210213","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1097\/00000542-200205000-00025","article-title":"Thiopental inhibits the activation of nuclear factor B.","volume":"96","author":"Loop","year":"2002","journal-title":"Anesthesiology"},{"key":"R44-12-20210213","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1038\/nature03491","article-title":"IKK limits macrophage NF-B activation and contributes to the resolution of inflammation.","volume":"434","author":"Lawrence","year":"2005","journal-title":"Nature"},{"key":"R45-12-20210213","doi-asserted-by":"crossref","first-page":"C422","DOI":"10.1152\/ajpcell.00507.2003","article-title":"Hypothermia prolongs activation of NF-B and augments generation of inflammatory cytokines.","volume":"287","author":"Fairchild","year":"2004","journal-title":"Am J Physiol Cell Physiol"},{"key":"R46-12-20210213","doi-asserted-by":"crossref","first-page":"C1114","DOI":"10.1152\/ajpcell.00152.2005","article-title":"Hypothermia enhances phosphorylation of IB kinase and prolongs nuclear localization of NF-B in lipopolysaccharide-activated macrophages.","volume":"289","author":"Fairchild","year":"2005","journal-title":"Am J Physiol Cell Physiol"},{"key":"R47-12-20210213","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.3181\/0904-RM-137","article-title":"NF-kappaB independent activation of a series of proinflammatory genes by hydrogen sulfide.","volume":"234","author":"Stuhlmeier","year":"2009","journal-title":"Exp Biol Med"}],"container-title":["Shock"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.lww.com\/00024382-201104000-00012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T15:12:49Z","timestamp":1740582769000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00024382-201104000-00012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":47,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/shk.0b013e3181ffff0e","relation":{},"ISSN":["1073-2322"],"issn-type":[{"value":"1073-2322","type":"print"}],"subject":[],"published":{"date-parts":[[2011,4]]}}}