{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:25:55Z","timestamp":1786119955683,"version":"build-2736575974"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1097\/shk.0b013e318228f614","type":"journal-article","created":{"date-parts":[[2011,6,23]],"date-time":"2011-06-23T07:43:49Z","timestamp":1308815029000},"page":"402-409","source":"Crossref","is-referenced-by-count":13,"title":["The Angiotensin-Converting Enzyme Inhibitor Captopril Inhibits Poly(Adp-Ribose) Polymerase Activation and Exerts Beneficial Effects in an Ovine Model of Burn and Smoke Injury"],"prefix":"10.1097","volume":"36","author":[{"given":"Sven","family":"Asmussen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Bartha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabor","family":"Olah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Sbrana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian W.","family":"Rehberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perenlei","family":"Enkhbaatar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hal K.","family":"Hawkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Cox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillian D.","family":"Traber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel L.","family":"Traber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Csaba","family":"Szabo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"2","key":"R2-13-20210213","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1042\/CS20040135","article-title":"Pathophysiology of acute lung injury in combined burn and smoke inhalation injury.","volume":"107","author":"Enkhbaatar","year":"2004","journal-title":"Clin Sci (Lond)"},{"issue":"4","key":"R3-13-20210213","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0305-4179(00)00127-3","article-title":"The involvement of free radicals in burn injury: a review.","volume":"27","author":"Latha","year":"2001","journal-title":"Burns"},{"issue":"1","key":"R4-13-20210213","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/BCR.0b013e3181923bf3","article-title":"Tocopherol as treatment for lung injury associated with burn and smoke inhalation.","volume":"30","author":"Traber","year":"2009","journal-title":"J Burn Care Res"},{"issue":"5","key":"R5-13-20210213","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/nrd1718","article-title":"Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors.","volume":"4","author":"Jagtap","year":"2005","journal-title":"Nat Rev Drug Discov"},{"issue":"1","key":"R6-13-20210213","doi-asserted-by":"crossref","first-page":"2","DOI":"10.2353\/ajpath.2008.080019","article-title":"Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease.","volume":"173","author":"Pacher","year":"2008","journal-title":"Am J Pathol"},{"issue":"6","key":"R7-13-20210213","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s00383-005-1409-6","article-title":"Poly(ADP-ribose) synthetase inhibition reduces oxidative and nitrosative organ damage after thermal injury.","volume":"21","author":"Avlan","year":"2005","journal-title":"Pediatr Surg Int"},{"issue":"3","key":"R8-13-20210213","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1164\/ajrccm.165.3.2106050","article-title":"Activation of poly(ADP-Ribose) polymerase-1 is a central mechanism of lipopolysaccharide-induced acute lung inflammation.","volume":"165","author":"Liaudet","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"R9-13-20210213","doi-asserted-by":"crossref","first-page":"L240","DOI":"10.1152\/ajplung.00319.2002","article-title":"Effect of PARP inhibition on burn and smoke inhalation injury in sheep.","volume":"285","author":"Shimoda","year":"2003","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"3","key":"R10-13-20210213","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/01.shk.0000110621.42625.10","article-title":"Activation of poly(ADP-ribose) polymerase in circulating leukocytes during myocardial infarction.","volume":"21","author":"Murthy","year":"2004","journal-title":"Shock"},{"issue":"9-10","key":"R11-13-20210213","doi-asserted-by":"crossref","first-page":"221","DOI":"10.2119\/2006-00055.Toth-Zsamboki","article-title":"Activation of poly(ADP-ribose) polymerase by myocardial ischemia and coronary reperfusion in human circulating leukocytes.","volume":"12","author":"Toth-Zsamboki","year":"2006","journal-title":"Mol Med"},{"issue":"2","key":"R12-13-20210213","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1124\/jpet.105.090480","article-title":"Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation.","volume":"315","author":"Mabley","year":"2005","journal-title":"J Pharmacol Exp Ther"},{"issue":"3-4","key":"R13-13-20210213","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.lfs.2007.11.001","article-title":"Treatment with insulin inhibits poly(ADP-ribose)polymerase activation in a rat model of endotoxemia.","volume":"82","author":"Horvath","year":"2008","journal-title":"Life Sci"},{"key":"R14-13-20210213","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/SHK.0b013e318212988c","article-title":"Burn and smoke injury activates poly(ADP-ribose)polymerase in circulating leukocytes.","volume":"36","author":"Bartha","year":"2011","journal-title":"Shock"},{"issue":"3","key":"R15-13-20210213","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1152\/physrev.00036.2005","article-title":"Physiology of local renin-angiotensin systems.","volume":"86","author":"Paul","year":"2006","journal-title":"Physiol Rev"},{"key":"R16-13-20210213","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1097\/00004630-198511000-00007","article-title":"Pulmonary edema and compliance changes following smoke inhalation.","volume":"6","author":"Traber","year":"1985","journal-title":"J Burn Care Rehabil"},{"issue":"2","key":"R17-13-20210213","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.cardiores.2006.04.015","article-title":"Redox signaling in angiogenesis: role of NADPH oxidase.","volume":"71","author":"Ushio-Fukai","year":"2006","journal-title":"Cardiovasc Res"},{"issue":"9-10","key":"R18-13-20210213","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1089\/ars.2005.7.1315","article-title":"Redox-dependent protein kinase regulation by angiotensin II: mechanistic insights and its pathophysiology.","volume":"7","author":"Ohtsu","year":"2005","journal-title":"Antioxid Redox Signal"},{"issue":"6","key":"R19-13-20210213","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1007\/s00424-010-0808-2","article-title":"Nitric oxide and oxidative stress in vascular disease.","volume":"459","author":"Forstermann","year":"2010","journal-title":"Pflugers Arch"},{"issue":"4","key":"R21-13-20210213","doi-asserted-by":"crossref","first-page":"H1545","DOI":"10.1152\/ajpheart.01124.2005","article-title":"Poly(ADP-ribose) polymerase-1-deficient mice are protected from angiotensin II-induced cardiac hypertrophy.","volume":"291","author":"Pillai","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"2","key":"R22-13-20210213","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/path.2277","article-title":"Cellular and molecular mechanisms of fibrosis.","volume":"214","author":"Wynn","year":"2008","journal-title":"J Pathol"},{"issue":"3","key":"R23-13-20210213","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1097\/BCR.0b013e3181a28ddb","article-title":"Transforming growth factor- and angiotensin in fibrosis and burn injuries.","volume":"30","author":"Gabriel","year":"2009","journal-title":"J Burn Care Res"},{"key":"R24-13-20210213","first-page":"1","article-title":"Angiotensin-1-converting enzyme activity as index of pulmonary damage in thermal injury with or without smoke inhalation.","volume":"22","author":"Brizio-Molteni","year":"1992","journal-title":"Ann Clin Lab Sci"},{"issue":"6","key":"R25-13-20210213","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.1152\/japplphysiol.00514.2006","article-title":"Angiotensin-converting enzyme inhibitor captopril attenuates ventilator-induced lung injury in rats.","volume":"102","author":"Jiang","year":"2007","journal-title":"J Appl Physiol"},{"issue":"6","key":"R26-13-20210213","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1097\/CCM.0b013e31817c911d","article-title":"Captopril decreases plasminogen activator inhibitor-1 in rats with ventilator-induced lung injury.","volume":"36","author":"Chen","year":"2008","journal-title":"Crit Care Med"},{"key":"R27-13-20210213","first-page":"1979","article-title":"Role of nitric oxide in shock: the large animal perspective.","volume":"14","author":"Lange","year":"2010","journal-title":"Front Biosci"},{"key":"R28-13-20210213","doi-asserted-by":"crossref","first-page":"18","DOI":"10.2741\/s43","article-title":"The role of nitric oxide and reactive nitrogen species in experimental ARDS.","volume":"2","author":"Rehberg","year":"2010","journal-title":"Front Biosci (Schol Ed)"}],"container-title":["Shock"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00024382-201110000-00013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T19:30:15Z","timestamp":1786044615000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00024382-201110000-00013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/shk.0b013e318228f614","relation":{},"ISSN":["1073-2322"],"issn-type":[{"value":"1073-2322","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]}}}