{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T10:03:53Z","timestamp":1791021833931,"version":"4.1.0"},"reference-count":51,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1097\/sla.0b013e31815c2ca3","type":"journal-article","created":{"date-parts":[[2009,3,5]],"date-time":"2009-03-05T02:51:00Z","timestamp":1236221460000},"page":"966-975","source":"Crossref","is-referenced-by-count":239,"title":["Is There Still a Role for Total Pancreatectomy?"],"prefix":"10.1097","volume":"246","author":[{"given":"Michael W.","family":"M\u00fcller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Friess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Kleeff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Dahmen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulf","family":"Hinz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Breisch-Girbig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fcralp O.","family":"Ceyhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus W.","family":"B\u00fcchler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-8-20210203","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.amjsurg.2006.10.010","article-title":"Pancreaticojejunostomy versus pancreaticogastrostomy: systematic review and meta-analysis.","volume":"193","author":"Wente","year":"2007","journal-title":"Am J Surg"},{"key":"R2-8-20210203","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/0002-9610(54)90038-0","article-title":"Cancer of the pancreas; a plea for total pancreatectomy.","volume":"87","author":"Ross","year":"1954","journal-title":"Am J Surg"},{"key":"R3-8-20210203","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1097\/00000658-195810000-00017","article-title":"Carcinoma of the pancreatico-duodenal area; operability and choice of procedure.","volume":"148","author":"Porter","year":"1958","journal-title":"Ann Surg"},{"key":"R4-8-20210203","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1097\/00000658-197010000-00006","article-title":"Total pancreatectomy.","volume":"172","author":"ReMine","year":"1970","journal-title":"Ann Surg"},{"key":"R5-8-20210203","first-page":"418","article-title":"Total pancreatectomy. An objective analysis of its use in pancreatic cancer.","volume":"40","author":"Sarr","year":"1993","journal-title":"Hepatogastroenterology"},{"key":"R6-8-20210203","article-title":"Surgical Disease of the Pancreas.","author":"Howard","year":"1960"},{"key":"R7-8-20210203","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0002-9610(86)90024-3","article-title":"Decreased morbidity and mortality after pancreatoduodenectomy.","volume":"151","author":"Grace","year":"1986","journal-title":"Am J Surg"},{"key":"R8-8-20210203","first-page":"347","article-title":"Is proximal pancreatoduodenectomy with pyloric preservation superior to total pancreatectomy?","volume":"105","author":"McAfee","year":"1989","journal-title":"Surgery"},{"key":"R9-8-20210203","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1097\/00000658-199108000-00007","article-title":"Metabolic consequences of (regional) total pancreatectomy.","volume":"214","author":"Dresler","year":"1991","journal-title":"Ann Surg"},{"key":"R10-8-20210203","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1056\/NEJM199309303291401","article-title":"The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group.","volume":"329","year":"1993","journal-title":"N Engl J Med"},{"key":"R11-8-20210203","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/j.1572-0241.2000.01764.x","article-title":"Outcome after surgical resection of intraductal papillary and mucinous tumors of the pancreas.","volume":"95","author":"Cuillerier","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"R12-8-20210203","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/01.mpa.0000153337.58105.47","article-title":"Renal cancer cell metastasis into the pancreas: a single-center experience and overview of the literature.","volume":"30","author":"Wente","year":"2005","journal-title":"Pancreas"},{"key":"R13-8-20210203","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","article-title":"The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology.","volume":"85","author":"Aaronson","year":"1993","journal-title":"J Natl Cancer Inst"},{"key":"R14-8-20210203","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/S0959-8049(00)00447-0","article-title":"Reference data for the quality of life questionnaire EORTC QLQ-C30 in the general German population.","volume":"37","author":"Schwarz","year":"2001","journal-title":"Eur J Cancer"},{"key":"R15-8-20210203","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S0959-8049(99)00047-7","article-title":"Development of a disease specific quality of life (QoL) questionnaire module to supplement the EORTC core cancer QoL questionnaire, the QLQ-C30 in patients with pancreatic cancer. EORTC Study Group on Quality of Life.","volume":"35","author":"Fitzsimmons","year":"1999","journal-title":"Eur J Cancer"},{"key":"R16-8-20210203","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1111\/j.1572-0241.2005.40859.x","article-title":"Symptoms and quality of life in chronic pancreatitis assessed by structured interview and the EORTC QLQ-C30 and QLQ-PAN26.","volume":"100","author":"Fitzsimmons","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"R17-8-20210203","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1097\/01.sla.0000247970.43080.23","article-title":"Middle segmental pancreatic resection: an option to treat benign pancreatic body lesions.","volume":"244","author":"Muller","year":"2006","journal-title":"Ann Surg"},{"key":"R18-8-20210203","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1001\/archsurg.1975.01360110052010","article-title":"Further evaluation of total pancreatectomy.","volume":"110","author":"Pliam","year":"1975","journal-title":"Arch Surg"},{"key":"R19-8-20210203","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/S0002-9610(05)80126-6","article-title":"A reappraisal of total pancreatectomy for pancreatic cancer: results from U.S. Veterans Affairs hospitals, 1987\u20131991.","volume":"168","author":"Swope","year":"1994","journal-title":"Am J Surg"},{"key":"R20-8-20210203","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s002689910013","article-title":"Pylorus-preserving total pancreatectomy for pancreatic cancer.","volume":"24","author":"Sugiyama","year":"2000","journal-title":"World J Surg"},{"key":"R21-8-20210203","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1159\/000050128","article-title":"Pylorus-preserving total pancreatectomy. Early and late results.","volume":"18","author":"Wagner","year":"2001","journal-title":"Dig Surg"},{"key":"R22-8-20210203","first-page":"1585","article-title":"Total pancreatectomy for intraductal papillary-mucinous tumor of the pancreas: reappraisal of total pancreatectomy.","volume":"52","author":"Yamaguchi","year":"2005","journal-title":"Hepatogastroenterology"},{"key":"R23-8-20210203","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1097\/01.sla.0000114132.47816.dd","article-title":"Intraductal papillary mucinous neoplasms of the pancreas: an analysis of clinicopathologic features and outcome.","volume":"239","author":"D\u2019Angelica","year":"2004","journal-title":"Ann Surg"},{"key":"R24-8-20210203","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/S0003-3944(02)00794-0","article-title":"[Total pancreatectomy for mucinous pancreatic tumor].","volume":"127","author":"Blanchet","year":"2002","journal-title":"Ann Chir"},{"key":"R25-8-20210203","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s00104-005-1113-z","article-title":"[Prophylactic pancreas surgery].","volume":"77","author":"Langer","year":"2006","journal-title":"Chirurg"},{"key":"R26-8-20210203","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s11864-005-0046-6","article-title":"Management strategies for patients with hereditary pancreatic cancer.","volume":"6","author":"Brentnall","year":"2005","journal-title":"Curr Treat Options Oncol"},{"key":"R27-8-20210203","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s10689-005-5672-4","article-title":"Restorative proctocolectomy and ileal pouch-anal anastomosis for familial adenomatous polyposis revisited.","volume":"5","author":"Kartheuser","year":"2006","journal-title":"Fam Cancer"},{"key":"R28-8-20210203","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1001\/archsurg.1995.01430030065013","article-title":"Standards for pancreatic resection in the 1990s.","volume":"130","author":"Fernandez-del","year":"1995","journal-title":"Arch Surg"},{"key":"R29-8-20210203","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/bjs.1800740112","article-title":"Duodenum-preserving total pancreatectomy for end stage chronic pancreatitis.","volume":"74","author":"Lambert","year":"1987","journal-title":"Br J Surg"},{"key":"R30-8-20210203","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/00000658-198801000-00009","article-title":"The complications of pancreatectomy.","volume":"207","author":"Trede","year":"1988","journal-title":"Ann Surg"},{"key":"R31-8-20210203","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/BF01658311","article-title":"Results of partial and total pancreaticoduodenectomy in 117 patients with chronic pancreatitis.","volume":"5","author":"Gall","year":"1981","journal-title":"World J Surg"},{"key":"R32-8-20210203","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1001\/archsurg.135.5.517","article-title":"Pancreatoduodenectomy for chronic pancreatitis: long-term results in 105 patients.","volume":"135","author":"Sakorafas","year":"2000","journal-title":"Arch Surg"},{"key":"R33-8-20210203","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1097\/00000658-199709000-00004","article-title":"Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes.","volume":"226","author":"Yeo","year":"1997","journal-title":"Ann Surg"},{"key":"R34-8-20210203","first-page":"425","article-title":"Low mortality following resection for pancreatic and periampullary tumours in 1026 patients: UK survey of specialist pancreatic units.","volume":"85","author":"van Berge Henegouwen","year":"1998","journal-title":"Br J Surg"},{"key":"R35-8-20210203","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1046\/j.1365-2168.2000.01465.x","article-title":"Pancreatic fistula after pancreatic head resection.","volume":"87","author":"Buchler","year":"2000","journal-title":"Br J Surg"},{"key":"R36-8-20210203","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1001\/archsurg.138.12.1310","article-title":"Changes in morbidity after pancreatic resection: toward the end of completion pancreatectomy.","volume":"138","author":"Buchler","year":"2003","journal-title":"Arch Surg"},{"key":"R37-8-20210203","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/j.gassur.2006.04.002","article-title":"Postoperative morbidity and long-term survival after pancreaticoduodenectomy with superior mesenterico-portal vein resection.","volume":"10","author":"Riediger","year":"2006","journal-title":"J Gastrointest Surg"},{"key":"R38-8-20210203","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1001\/archsurg.139.1.16","article-title":"Completion pancreatectomy for postoperative peritonitis after pancreaticoduodenectomy: early and late outcome.","volume":"139","author":"Gueroult","year":"2004","journal-title":"Arch Surg"},{"key":"R39-8-20210203","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.dld.2006.01.022","article-title":"Diabetic control after total pancreatectomy.","volume":"38","author":"Jethwa","year":"2006","journal-title":"Dig Liver Dis"},{"key":"R40-8-20210203","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1002\/bjs.5047","article-title":"Incidence and management of pancreatic leakage after pancreatoduodenectomy.","volume":"92","author":"de Castro","year":"2005","journal-title":"Br J Surg"},{"key":"R41-8-20210203","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.gassur.2005.05.014","article-title":"Quality-of-life after total pancreatectomy: is it really that bad on long-term follow-up?","volume":"9","author":"Billings","year":"2005","journal-title":"J Gastrointest Surg"},{"key":"R42-8-20210203","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1136\/gut.29.3.358","article-title":"Total pancreatectomy for chronic pancreatitis.","volume":"29","author":"Linehan","year":"1988","journal-title":"Gut"},{"key":"R43-8-20210203","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0140-6736(98)07019-6","article-title":"Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.","volume":"352","year":"1998","journal-title":"Lancet"},{"key":"R44-8-20210203","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1002\/bjs.4324","article-title":"Duodenum- and spleen-preserving total pancreatectomy for end-stage chronic pancreatitis.","volume":"90","author":"Alexakis","year":"2003","journal-title":"Br J Surg"},{"key":"R45-8-20210203","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1056\/NEJM197706022962202","article-title":"Ketoacidosis in pancreatectomized man.","volume":"296","author":"Barnes","year":"1977","journal-title":"N Engl J Med"},{"key":"R46-8-20210203","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/j.1464-5491.1993.tb00051.x","article-title":"Frequency and morbidity of severe hypoglycaemia in insulin-treated diabetic patients.","volume":"10","author":"MacLeod","year":"1993","journal-title":"Diabet Med"},{"key":"R47-8-20210203","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1097\/00000658-199506000-00011","article-title":"Pancreaticoduodenectomy for cancer of the head of the pancreas: 201 patients.","volume":"221","author":"Yeo","year":"1995","journal-title":"Ann Surg"},{"key":"R48-8-20210203","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1002\/bjs.4484","article-title":"Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinoma.","volume":"91","author":"Wagner","year":"2004","journal-title":"Br J Surg"},{"key":"R49-8-20210203","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1056\/NEJMoa032295","article-title":"A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer.","volume":"350","author":"Neoptolemos","year":"2004","journal-title":"N Engl J Med"},{"key":"R50-8-20210203","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1177\/000313480607200403","article-title":"Total pancreatectomy for the treatment of chronic pancreatitis: indications, outcomes, and recommendations.","volume":"72","author":"Behrman","year":"2006","journal-title":"Am Surg"},{"key":"R51-8-20210203","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1097\/00000658-200112000-00007","article-title":"Influence of resection margins on survival for patients with pancreatic cancer treated by adjuvant chemoradiation and\/or chemotherapy in the ESPAC-1 randomized controlled trial.","volume":"234","author":"Neoptolemos","year":"2001","journal-title":"Ann Surg"}],"container-title":["Annals of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.lww.com\/00000658-200712000-00008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,10]],"date-time":"2021-04-10T07:28:08Z","timestamp":1618039688000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00000658-200712000-00008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12]]},"references-count":51,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/sla.0b013e31815c2ca3","relation":{},"ISSN":["0003-4932"],"issn-type":[{"value":"0003-4932","type":"print"}],"subject":[],"published":{"date-parts":[[2007,12]]}}}