{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T05:58:44Z","timestamp":1792735124658,"version":"4.5.0"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1097\/sla.0b013e3181a63c10","type":"journal-article","created":{"date-parts":[[2009,7,10]],"date-time":"2009-07-10T03:31:49Z","timestamp":1247196709000},"page":"1-6","source":"Crossref","is-referenced-by-count":279,"title":["Normothermic Perfusion"],"prefix":"10.1097","volume":"250","author":[{"given":"Jens","family":"Brockmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srikanth","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantin","family":"Coussios","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Pigott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dino","family":"Guirriero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Hughes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Morovat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debabrata","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Winter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Friend","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-1-20210203","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1002\/jez.1402650413","article-title":"Cold shock damage is due to lipid phase transitions in cell membranes: a demonstration using sperm as a model.","volume":"265","author":"Drobnis","year":"1993","journal-title":"J Exp Zool"},{"key":"R2-1-20210203","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1097\/00007890-199205000-00001","article-title":"Preservation and reperfusion injuries in liver allografts. An overview and synthesis of current studies.","volume":"53","author":"Clavien","year":"1992","journal-title":"Transplantation"},{"key":"R3-1-20210203","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1097\/00007890-199105000-00013","article-title":"Effect of cold ischemia time on the early outcome of human hepatic allografts preserved with UW solution.","volume":"51","author":"Furukawa","year":"1991","journal-title":"Transplantation"},{"key":"R4-1-20210203","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/0140-6736(92)92559-X","article-title":"Effect of extended cold ischaemia with UW solution on graft function after liver transplantation [comments].","volume":"340","author":"Adam","year":"1992","journal-title":"Lancet"},{"key":"R5-1-20210203","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1097\/00007890-200008270-00002","article-title":"Assessment of graft function before liver transplantation: quest for the lost ark?","volume":"70","author":"Vilca Melendez","year":"2000","journal-title":"Transplantation"},{"key":"R6-1-20210203","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1002\/lt.20268","article-title":"Liver transplantation from non-heart-beating donors: current status and future prospects.","volume":"10","author":"Reddy","year":"2004","journal-title":"Liver Transplant"},{"key":"R7-1-20210203","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1056\/NEJM199801223380403","article-title":"Transplantation of kidneys from donors whose hearts have stopped beating.","volume":"338","author":"Cho","year":"1998","journal-title":"N Engl J Med"},{"key":"R8-1-20210203","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1097\/01.sla.0000186178.07110.92","article-title":"Donation after cardiac death: the university of Wisconsin experience with liver transplantation.","volume":"242","author":"Foley","year":"2005","journal-title":"Ann Surg"},{"issue":"suppl 6","key":"R9-1-20210203","first-page":"13","article-title":"Hypothermia and cellular physiology.","volume":"50","author":"Zachariassen","year":"1991","journal-title":"Arctic Med Res"},{"key":"R10-1-20210203","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1053\/jhep.2002.31869","article-title":"Cold-induced apoptosis of rat liver cells in university of Wisconsin solution: the central role of chelatable iron.","volume":"35","author":"Kerkweg","year":"2002","journal-title":"Hepatology"},{"key":"R11-1-20210203","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1002\/hep.1840190213","article-title":"Reperfusion injury, antioxidants and hemodynamics during orthotopic liver transplantation.","volume":"19","author":"Goode","year":"1994","journal-title":"Hepatology"},{"issue":"4","key":"R12-1-20210203","first-page":"G564","article-title":"Circulating xanthine oxidase: potential mediator of ischemic injury.","volume":"258","author":"Yokoyama","year":"1990","journal-title":"Am J Physiol"},{"key":"R13-1-20210203","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1080\/10715760310001626266","article-title":"Oxidative stress underlies the mechanism for Ca(2+)-induced permeability transition of mitochondria.","volume":"38","author":"Kanno","year":"2004","journal-title":"Free Radic Res"},{"key":"R14-1-20210203","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.bbabio.2006.02.019","article-title":"Production of reactive oxygen species in mitochondria of HeLa cells under oxidative stress.","volume":"1757","author":"Chernyak","year":"2006","journal-title":"Biochim Biophys Acta"},{"key":"R15-1-20210203","doi-asserted-by":"crossref","first-page":"3355","DOI":"10.1096\/fasebj.4.15.2253850","article-title":"Neutrophils contribute to ischemia\/reperfusion injury in rat liver in vivo.","volume":"4","author":"Jaeschke","year":"1990","journal-title":"Faseb J"},{"key":"R16-1-20210203","doi-asserted-by":"crossref","first-page":"6465","DOI":"10.1073\/pnas.85.17.6465","article-title":"Normal oxidative damage to mitochondrial and nuclear DNA is extensive.","volume":"85","author":"Richter","year":"1988","journal-title":"Proc Natl Acad Sci USA"},{"key":"R17-1-20210203","doi-asserted-by":"crossref","first-page":"11401","DOI":"10.1074\/jbc.273.19.11401","article-title":"Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss.","volume":"273","author":"Cai","year":"1998","journal-title":"J Biol Chem"},{"key":"R18-1-20210203","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1749-6632.2000.tb06187.x","article-title":"Protein oxidation.","volume":"899","author":"Stadtman","year":"2000","journal-title":"Ann N Y Acad Sci"},{"key":"R19-1-20210203","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1515\/BC.2002.050","article-title":"Mammalian cell injury induced by hypothermia- the emerging role for reactive oxygen species.","volume":"383","author":"Rauen","year":"2002","journal-title":"Biol Chem"},{"key":"R20-1-20210203","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1097\/00007890-200106270-00005","article-title":"Comparative evaluation of Celsior solution versus Viaspan in a pig liver transplantation model.","volume":"71","author":"Audet","year":"2001","journal-title":"Transplantation"},{"key":"R21-1-20210203","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1097\/00007890-200204270-00005","article-title":"Successful extracorporeal porcine liver perfusion for 72 hour.","volume":"73","author":"Butler","year":"2002","journal-title":"Transplantation"},{"key":"R22-1-20210203","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1097\/00007890-200203150-00008","article-title":"Advantages of normothermic perfusion over cold storage in liver preservation.","volume":"73","author":"Imber","year":"2002","journal-title":"Transplantation"},{"key":"R23-1-20210203","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1046\/j.1365-2168.2002.02052.x","article-title":"Extended preservation of non-heart-beating donor livers with normothermic machine perfusion.","volume":"89","author":"St Peter","year":"2002","journal-title":"Br J Surg"},{"key":"R24-1-20210203","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1097\/01.TP.0000119206.63326.56","article-title":"Preservation of porcine non-heart-beating donor livers by sequential cold storage and warm perfusion.","volume":"77","author":"Reddy","year":"2004","journal-title":"Transplantation"},{"key":"R25-1-20210203","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1097\/00000658-200101000-00017","article-title":"Liver transplantation after organ preservation with normothermic extracorporeal perfusion.","volume":"233","author":"Schon","year":"2001","journal-title":"Ann Surg"},{"key":"R26-1-20210203","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1053\/jhep.2001.22002","article-title":"Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis?","volume":"33","author":"Gujral","year":"2001","journal-title":"Hepatology"},{"key":"R27-1-20210203","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1097\/00007890-200103270-00005","article-title":"Pretransplantation prognostic testing on damaged kidneys during ex vivo warm perfusion.","volume":"71","author":"Stubenitsky","year":"2001","journal-title":"Transplantation"},{"key":"R28-1-20210203","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.1016\/S0041-1345(02)03449-8","article-title":"Transfection and transgene expression in a human kidney during ex vivo warm perfusion.","volume":"34","author":"Brasile","year":"2002","journal-title":"Transplant Proc"},{"key":"R29-1-20210203","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/00007890-200108150-00007","article-title":"Functional metabolic characteristics of intact pig livers during prolonged extracorporeal perfusion: potential for a unique biological liver-assist device.","volume":"72","author":"Borie","year":"2001","journal-title":"Transplantation"},{"key":"R30-1-20210203","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1177\/039139889301601010","article-title":"Extracorporeal liver perfusion: applications of an improved model for experimental studies of the liver.","volume":"16","author":"Neuhaus","year":"1993","journal-title":"Int J Artif Organs"},{"key":"R31-1-20210203","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1046\/j.1523-1755.2000.00445.x","article-title":"A comparison of the results of renal transplantation from non-heart-beating, conventional cadaveric, and living donors.","volume":"58","author":"Nicholson","year":"2000","journal-title":"Kidney Int"},{"key":"R32-1-20210203","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/01.sla.0000103063.82181.2c","article-title":"Survival following liver transplantation from non-heart-beating donors.","volume":"239","author":"Abt","year":"2004","journal-title":"Ann Surg"},{"key":"R33-1-20210203","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1159\/000008724","article-title":"Evaluation of ischemic injury during liver procurement from non-heart- beating donors.","volume":"31","author":"Garcia-Valdecasas","year":"1999","journal-title":"Eur Surg Res"},{"issue":"4","key":"R34-1-20210203","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1002\/hep.1840200410","article-title":"Selecting the donor liver: risk factors for poor function after orthotopic liver transplantation [comments].","volume":"20","author":"Strasberg","year":"1994","journal-title":"Hepatology"},{"key":"R35-1-20210203","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1111\/j.1432-2277.1998.tb00831.x","article-title":"Liver conditioning after cardiac arrest: the use of normothermic recirculation in an experimental animal model.","volume":"11","author":"Garcia-Valdecasas","year":"1998","journal-title":"Transplant Int"}],"container-title":["Annals of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00000658-200907000-00001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:57:27Z","timestamp":1786039047000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00000658-200907000-00001"}},"subtitle":["A New Paradigm for Organ Preservation"],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/sla.0b013e3181a63c10","relation":{},"ISSN":["0003-4932"],"issn-type":[{"value":"0003-4932","type":"print"}],"subject":[],"published":{"date-parts":[[2009,7]]}}}